Reviewed, UniProtKB/Swiss-Prot P93804 (PGMC1_MAIZE)

Names and origin

Protein names	Recommended name:     Phosphoglucomutase, cytoplasmic 1       Short name=PGM 1     EC=5.4.2.2 Alternative name(s):     Glucose phosphomutase 1
Organism	Zea mays (Maize)
Taxonomic identifier	4577 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › PACCAD clade › Panicoideae › Andropogoneae › Zea

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This enzyme participates in both the breakdown and synthesis of glucose By similarity.
Catalytic activity	Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 583	583	Phosphoglucomutase, cytoplasmic 1		PRO_0000147801
Sites
	Active site	124	1	Phosphoserine intermediate By similarity
	Metal binding	124	1	Magnesium; via phosphate group By similarity
	Metal binding	300	1	Magnesium By similarity
	Metal binding	302	1	Magnesium By similarity
	Metal binding	304	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	P93804-1 [UniParc]. Last modified May 1, 1999. Version 2. Checksum: 4C19D15AEF4A6D80	FASTA	583	63,097
	10 20 30 40 50 60 MGLFTVTKKA TTPFDGQKPG TSGLRKKVTV FQQPHYLQNF VQSTFNALPV DQVRGATIVV 70 80 90 100 110 120 SGDGRYFSKD AVQIITKMAA ANGVRRVWVG QNSLMSTPAV SAVIRERVGA DGSKATGAFI 130 140 150 160 170 180 LTASHNPGGP KEDFGIKYNM GNGGPAPESV TDKIFSNTTT ISEYLISEDL PDVDISVVGV 190 200 210 220 230 240 TSFSGPEGPF DVDVFDSSVD YIKLMKTIFD FEAIKKLLTS PKFTFCYDAL HGVAGAYAKH 250 260 270 280 290 300 IFVEELGADE SSLLNCVPKE DFGGGHPDPN LTYAKELVER MGLGKSSSNV EPPEFGAAAD 310 320 330 340 350 360 GDADRNMILG KRFFVTPSDS VAIIAANAVQ SIPYFASGLK GVARSMPTSA ALDVVAKNLN 370 380 390 400 410 420 LKFFEVPTGW KFFGNLMDAG MCSICGEESF GTGSDHIREK DGIWAVLAWL SIIAFKNKDN 430 440 450 460 470 480 LGGDKLVTVE DIVRQHWATY GRHYYTRYDY ENVDAGAAKE LMANLVSMQS SLSDVNKLVK 490 500 510 520 530 540 EIRSDVSEVV AADEFEYKDP VDGSVSKHQG IRYLFGDGSR LVFRLSGTGS VGATIRVYIE 550 560 570 580 QYERDSSKTG RDSQDALAPL VDVALKLSKM QEYTGRSAPT VIT

References

[1]

"Molecular and biochemical characterization of cytosolic phosphoglucomutase in maize: expression during development and in response to oxygen deprivation." Manjunath S., Lee C.-H.K., VanWinkle P., Bailey-Serres J. Plant Physiol. 117:997-1006(1998) [PubMed: 9662542] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. B73.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U89341 mRNA. Translation: AAC50048.1.
PIR	T04326.
RefSeq	NP_001105703.1.
UniGene	Zm.399
3D structure databases
HSSP	HSSP built from PDB template 3PMG based on UniProtKB P00949.
ModBase	Search...
Genome annotation databases
GeneID	542721.
Organism-specific databases
Gramene	P93804.
MaizeGDB	12543.
Enzyme and pathway databases
BRENDA	5.4.2.2. 289.
Family and domain databases
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGMC1_MAIZE

Accession

Primary (citable) accession number: P93804

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	May 1, 1999
Last modified:	June 16, 2009
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)