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P93746 (EC1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
EC protein homolog 1
Gene names
Ordered Locus Names:At2g42000
ORF Names:T6D20.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length84 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds 5 molecules of zinc. May have a role in Zn2+ homeostasis during embryogenesis By similarity.

Sequence similarities

Belongs to the metallothionein superfamily. Type 15 family.

Sequence caution

The sequence AAB63543.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence AEC10060.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   LigandMetal-binding
Metal-thiolate cluster
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: P93746-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8484EC protein homolog 1
PRO_0000197423

Experimental info

Sequence conflict681A → D in CAA83560. Ref.3
Sequence conflict831A → D in CAA83560. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 09D76F26CDF87676

FASTA848,290
        10         20         30         40         50         60 
MADTGKGSSV AGCNDSCGCP SPCPGGNSCR CRMREASAGD QGHMVCPCGE HCGCNPCNCP 

        70         80 
KTQTQTSAKG CTCGEGCTCA SCAT 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs."
Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C., Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R., Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J. expand/collapse author list , Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D., Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P., Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.
Plant J. 9:101-124(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-84.
Strain: cv. Columbia.
Tissue: Dry seed.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U90439 Genomic DNA. Translation: AAB63543.1. Different initiation.
CP002685 Genomic DNA. Translation: AEC10060.1. Different initiation.
Z32602 mRNA. Translation: CAA83560.1.
PIRG84848.
RefSeqNP_181731.1. NM_129764.1.
UniGeneAt.42759.

3D structure databases

ProteinModelPortalP93746.
SMRP93746. Positions 41-84.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID818800.
KEGGath:AT2G42000.

Organism-specific databases

TAIRAT2G42000.

Phylogenomic databases

eggNOGNOG304685.
HOGENOMHOG000243560.
InParanoidP93746.
PhylomeDBP93746.
ProtClustDBCLSN2683807.

Gene expression databases

GenevestigatorP93746.

Family and domain databases

InterProIPR000316. Metallthion_15.
[Graphical view]
PfamPF02068. Metallothio_PEC. 1 hit.
[Graphical view]
PRINTSPR00877. MTPLANTPEC.
ProtoNetSearch...

Entry information

Entry nameEC1_ARATH
AccessionPrimary (citable) accession number: P93746
Secondary accession number(s): F4ILY8, Q42258
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Metallothioneins

Classification of metallothioneins and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names