P93746 (EC1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
EC protein homolog 1

Gene names

Ordered Locus Names:	At2g42000
ORF Names:	T6D20.11

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	84 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Binds 5 molecules of zinc. May have a role in Zn2+ homeostasis during embryogenesis By similarity.
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.
Sequence caution	The sequence AAB63543.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. The sequence AEC10060.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Ligand	Metal-binding Metal-thiolate cluster Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: P93746-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 84	84	EC protein homolog 1		PRO_0000197423
Experimental info
	Sequence conflict	68	1	A → D in CAA83560. Ref.3
	Sequence conflict	83	1	A → D in CAA83560. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 09D76F26CDF87676	FASTA	84	8,290
	10 20 30 40 50 60 MADTGKGSSV AGCNDSCGCP SPCPGGNSCR CRMREASAGD QGHMVCPCGE HCGCNPCNCP 70 80 KTQTQTSAKG CTCGEGCTCA SCAT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs." Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C., Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R., Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J. , Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D., Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P., Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H. Plant J. 9:101-124(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-84. Strain: cv. Columbia. Tissue: Dry seed.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U90439 Genomic DNA. Translation: AAB63543.1. Different initiation. CP002685 Genomic DNA. Translation: AEC10060.1. Different initiation. Z32602 mRNA. Translation: CAA83560.1.
IPI	IPI00517684.
PIR	G84848.
RefSeq	NP_181731.1. NM_129764.1.
UniGene	At.42759.
3D structure databases
ProteinModelPortal	P93746.
SMR	P93746. Positions 41-84.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	818800.
KEGG	ath:AT2G42000.
Organism-specific databases
TAIR	At2g42000.
Phylogenomic databases
eggNOG	NOG304685.
HOGENOM	HOG000243560.
InParanoid	P93746.
PhylomeDB	P93746.
ProtClustDB	CLSN2683807.
Gene expression databases
ArrayExpress	P93746.
Genevestigator	P93746.
GermOnline	AT2G42000. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR000316. Metallthion_15. [Graphical view]
Pfam	PF02068. Metallothio_PEC. 1 hit. [Graphical view]
PRINTS	PR00877. MTPLANTPEC.
ProtoNet	Search...

Entry information

Entry name

EC1_ARATH

Accession

Primary (citable) accession number: P93746
Secondary accession number(s): F4ILY8, Q42258

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program