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Protein

Serpin-Z1B

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibits chymotrypsin and cathepsin G in vitro.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei358 – 359Reactive bond2

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin-Z1B
Alternative name(s):
TriaeZ1b
WSZ1b
WZS2
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Protein family/group databases

Allergomei5724. Tri a 33.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003345691 – 399Serpin-Z1BAdd BLAST399

Structurei

3D structure databases

ProteinModelPortaliP93693.
SMRiP93693.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni344 – 368RCLAdd BLAST25

Domaini

The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).By similarity

Sequence similaritiesi

Belongs to the serpin family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

P93693-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTLATDVR LSIAHQTRFA LRLASTISSN PKSAASNAAF SPVSLHSALS
60 70 80 90 100
LLAAGAGSAT RDQLVATLGT GEVEGGHALA EQVVQFVLAD ASSAGGPRVA
110 120 130 140 150
FANGVFVDAS LLLKPSFQEL AVCKYKAETQ SVDFQTKAAE VTTQVNSWVE
160 170 180 190 200
KVTSGRIKNI LPSGSVDNTT KLVLANALYF KGAWTDQFDS YGTKNDYFYL
210 220 230 240 250
LDGSSVQTPF MSSMDDDQYI SSSDGLKVLK LPYKQGGDNR QFSMYILLPE
260 270 280 290 300
APGGLSSLAE KLSAEPDFLE RHIPRQRVAI RQFKLPKFKI SFGMEASDLL
310 320 330 340 350
KCLGLQLPFS DEADFSEMVD SPMPQGLRVS SVFHQAFVEV NEQGTEAAAS
360 370 380 390
TAIKMVPQQA RPPSVMDFIA DHPFLFLLRE DISGVVLFMG HVVNPLLSS
Length:399
Mass (Da):43,033
Last modified:May 1, 1997 - v1
Checksum:i4A22615566B9A590
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11485 mRNA. Translation: CAA72273.1.
PIRiT06488.
UniGeneiTa.118.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11485 mRNA. Translation: CAA72273.1.
PIRiT06488.
UniGeneiTa.118.

3D structure databases

ProteinModelPortaliP93693.
SMRiP93693.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei5724. Tri a 33.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSPZ1B_WHEAT
AccessioniPrimary (citable) accession number: P93693
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 1, 1997
Last modified: May 10, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.