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Protein

Serpin-Z1B

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Inhibits chymotrypsin and cathepsin G in vitro.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei358 – 359Reactive bond2

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin-Z1B
Alternative name(s):
TriaeZ1b
WSZ1b
WZS2
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Protein family/group databases

Allergomei5724 Tri a 33

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003345691 – 399Serpin-Z1BAdd BLAST399

Proteomic databases

PRIDEiP93693

Expressioni

Gene expression databases

ExpressionAtlasiP93693 baseline

Structurei

3D structure databases

ProteinModelPortaliP93693
SMRiP93693
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni344 – 368RCLAdd BLAST25

Domaini

The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).By similarity

Sequence similaritiesi

Belongs to the serpin family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

P93693-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTLATDVR LSIAHQTRFA LRLASTISSN PKSAASNAAF SPVSLHSALS
60 70 80 90 100
LLAAGAGSAT RDQLVATLGT GEVEGGHALA EQVVQFVLAD ASSAGGPRVA
110 120 130 140 150
FANGVFVDAS LLLKPSFQEL AVCKYKAETQ SVDFQTKAAE VTTQVNSWVE
160 170 180 190 200
KVTSGRIKNI LPSGSVDNTT KLVLANALYF KGAWTDQFDS YGTKNDYFYL
210 220 230 240 250
LDGSSVQTPF MSSMDDDQYI SSSDGLKVLK LPYKQGGDNR QFSMYILLPE
260 270 280 290 300
APGGLSSLAE KLSAEPDFLE RHIPRQRVAI RQFKLPKFKI SFGMEASDLL
310 320 330 340 350
KCLGLQLPFS DEADFSEMVD SPMPQGLRVS SVFHQAFVEV NEQGTEAAAS
360 370 380 390
TAIKMVPQQA RPPSVMDFIA DHPFLFLLRE DISGVVLFMG HVVNPLLSS
Length:399
Mass (Da):43,033
Last modified:May 1, 1997 - v1
Checksum:i4A22615566B9A590
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11485 mRNA Translation: CAA72273.1
PIRiT06488
UniGeneiTa.118

Similar proteinsi

Entry informationi

Entry nameiSPZ1B_WHEAT
AccessioniPrimary (citable) accession number: P93693
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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