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P93541

- DHE3_SOLLC

UniProt

P93541 - DHE3_SOLLC

Protein

Glutamate dehydrogenase

Gene

GDH1

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 May 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei102 – 1021PROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: EnsemblPlants/Gramene
    2. cobalt ion binding Source: EnsemblPlants/Gramene
    3. copper ion binding Source: EnsemblPlants/Gramene
    4. glutamate dehydrogenase [NAD(P)+] activity Source: UniProtKB-EC
    5. zinc ion binding Source: EnsemblPlants/Gramene

    GO - Biological processi

    1. cellular amino acid metabolic process Source: InterPro
    2. regulation of nitrogen compound metabolic process Source: EnsemblPlants/Gramene
    3. response to absence of light Source: EnsemblPlants/Gramene
    4. response to cadmium ion Source: EnsemblPlants/Gramene
    5. response to salt stress Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-15559.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate dehydrogenase (EC:1.4.1.3)
    Short name:
    GDH
    Alternative name(s):
    Legdh1
    Gene namesi
    Name:GDH1
    OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
    Taxonomic identifieri4081 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
    ProteomesiUP000004994: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial matrix Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 412412Glutamate dehydrogenasePRO_0000182748Add
    BLAST

    Expressioni

    Tissue specificityi

    In roots, stems, leaves and flowers but not in fruits.

    Structurei

    3D structure databases

    ProteinModelPortaliP93541.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK00261.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000185. Glu_DH. 1 hit.
    PRINTSiPR00082. GLFDHDRGNASE.
    SMARTiSM00839. ELFV_dehydrog. 1 hit.
    [Graphical view]
    PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P93541-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNALAATNRN FKLAARLLGL DSKLELSLLI PFREIKVECT IPKDDGTLAS    50
    FVGFRVQHDN ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVANIPYGG 100
    AKGGIGCSPS DLSISELERL TRVFTQKIHD LIGIHTDVPA PDMGTNPQTM 150
    AWILDEYSKF HGYSPAVVTG KPVDLGGSLG RDAATGRGAL FATEALLNEH 200
    GKSVAGQRFV IQGFGNVGSW AAKLIHEQGG KVVAVSDITG AIKNEKGIDI 250
    ESLFKHVKET RGVKGFHDAH PIDANSILVE DCDVLIPAAL GGVINKDNHK 300
    LKIKAKYIIE AANHPTDPEA DEILSKKGVT ILPDIYANSG GVTVSYFEWV 350
    QNIQGFMWDE KKVNDELKTY MTRGFKDVKD MCKTHNCDLR MGAFTLGVNR 400
    VARATVLRGW EA 412
    Length:412
    Mass (Da):44,813
    Last modified:May 1, 1997 - v1
    Checksum:i83BC4138047A6BCA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U48695 mRNA. Translation: AAB39508.1.
    PIRiJC6317.
    RefSeqiNP_001233850.1. NM_001246921.1.
    UniGeneiLes.20253.

    Genome annotation databases

    GeneIDi544015.
    KEGGisly:544015.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U48695 mRNA. Translation: AAB39508.1 .
    PIRi JC6317.
    RefSeqi NP_001233850.1. NM_001246921.1.
    UniGenei Les.20253.

    3D structure databases

    ProteinModelPortali P93541.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 544015.
    KEGGi sly:544015.

    Phylogenomic databases

    KOi K00261.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-15559.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000185. Glu_DH. 1 hit.
    PRINTSi PR00082. GLFDHDRGNASE.
    SMARTi SM00839. ELFV_dehydrog. 1 hit.
    [Graphical view ]
    PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterisation of a glutamate dehydrogenase cDNA from tomato (Lycopersicon esculentum L.)."
      Purnell M.P., Stewart G.R., Botella J.R.
      Gene 186:249-254(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Pera.

    Entry informationi

    Entry nameiDHE3_SOLLC
    AccessioniPrimary (citable) accession number: P93541
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 1997
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3