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Reviewed, UniProtKB/Swiss-Prot P93541 (DHE3_SOLLC)

Last modified November 25, 2008. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glutamate dehydrogenase
      Short name=GDH
    EC=1.4.1.3
Alternative name(s):
    Legdh1
Gene names
Name: GDH1
OrganismSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifier4081 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.

Subcellular location

Mitochondrion matrixPotential.

Tissue specificity

In roots, stems, leaves and flowers but not in fruits.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords

   Cellular componentMitochondrion
   LigandNAD
   Molecular functionOxidoreductase

Gene Ontology (GO)

   Biological processamino acid metabolic process

Inferred from electronic annotation. Source: InterPro

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrial matrix

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionbinding

Inferred from electronic annotation. Source: InterPro

glutamate dehydrogenase [NAD(P)+] activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 412412Glutamate dehydrogenase
PRO_0000182748

Sites

Active site1021 By similarity

Sequences

Sequence LengthMass (Da)Tools
P93541-1 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: 83BC4138047A6BCA

FASTA41244,813
        10         20         30         40         50         60 
MNALAATNRN FKLAARLLGL DSKLELSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVANIPYGG AKGGIGCSPS DLSISELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGIHTDVPA PDMGTNPQTM AWILDEYSKF HGYSPAVVTG KPVDLGGSLG 

       190        200        210        220        230        240 
RDAATGRGAL FATEALLNEH GKSVAGQRFV IQGFGNVGSW AAKLIHEQGG KVVAVSDITG 

       250        260        270        280        290        300 
AIKNEKGIDI ESLFKHVKET RGVKGFHDAH PIDANSILVE DCDVLIPAAL GGVINKDNHK 

       310        320        330        340        350        360 
LKIKAKYIIE AANHPTDPEA DEILSKKGVT ILPDIYANSG GVTVSYFEWV QNIQGFMWDE 

       370        380        390        400        410 
KKVNDELKTY MTRGFKDVKD MCKTHNCDLR MGAFTLGVNR VARATVLRGW EA 

« Hide

References

[1]"Cloning and characterisation of a glutamate dehydrogenase cDNA from tomato (Lycopersicon esculentum L.)."
Purnell M.P., Stewart G.R., Botella J.R.
Gene 186:249-254(1997) [PubMed: 9074503] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Pera.

Cross-references

Sequence databases

U48695 mRNA. Translation: AAB39508.1.
PIRJC6317.
UniGeneLes.20253

3D structure databases

HSSPHSSP built from PDB template 1B26 based on UniProtKB P96110.
ModBaseSearch...

Family and domain databases

InterProIPR006095. Glu/Leu/Phe/Val_DHase.
IPR006096. Glu/Leu/Phe/Val_DHase_C.
IPR006097. Glu/Leu/Phe/Val_DHase_dimer.
IPR014362. Glu_DHase.
IPR016040. NAD(P)-bd.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR11606:SF2. GLFV_DH. 1 hit.
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHE3_SOLLC
AccessionPrimary (citable) accession number: P93541
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1997
Last modified: November 25, 2008
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents