Reviewed, UniProtKB/Swiss-Prot P93262 (PGMC_MESCR)

Names and origin

Protein names

Recommended name:
    Phosphoglucomutase, cytoplasmic
      Short name=PGM
    EC=5.4.2.2
Alternative name(s):
    Glucose phosphomutase

Gene names

Name:

PGM1

Organism

Mesembryanthemum crystallinum (Common ice plant)

Taxonomic identifier

3544 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Aizoaceae › Mesembryanthemum

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This enzyme participates in both the breakdown and synthesis of glucose By similarity.
Catalytic activity	Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 583	583	Phosphoglucomutase, cytoplasmic		PRO_0000147803
Sites
	Active site	124	1	Phosphoserine intermediate By similarity
	Metal binding	124	1	Magnesium; via phosphate group By similarity
	Metal binding	300	1	Magnesium By similarity
	Metal binding	302	1	Magnesium By similarity
	Metal binding	304	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	P93262-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: F7418E2CE4C716A2	FASTA	583	63,446
	10 20 30 40 50 60 MATFKVSRVE TKPYDGQKPG TSGLRKKVKV FAQPHYLENF VQSTFDALTA DKIKGKTLVV 70 80 90 100 110 120 SGDGRYYSEQ AIQTIIKMSA ANGVKSVWVG QDGLLSTPAV SAVIRERVGK DGSKASGAFI 130 140 150 160 170 180 LTASHNPGGP NEDFGIKYNM ENGGPAQEGV TNKIYENTTT IKEYLIAKEL PNVNISKTGV 190 200 210 220 230 240 TSFSGPDGQF DVEVFDATET YVKLMKSIFD FQAIKKLLSI PSFTFCYDAL HGVAGVYAKR 250 260 270 280 290 300 IFVDELGANE SSLLNCTPKE DFGGGHPDPN LTYAKELVER MGLGKSNTQG EPPEFGAAAD 310 320 330 340 350 360 GDADRNMILG KRFFVTPSDS VAIIAANAVE AIPYFSGGLK GVARSMPTSA ALDVVAKHLN 370 380 390 400 410 420 LKFFEVPTGW KFFGNLMDAG VCSICGEESF GTGSDHVREK DGIWAVLAWL SILAHKNKDN 430 440 450 460 470 480 LNGEKLVTVE DIVCQHWATY GRHYYTRYDY ENVDAGGAKE LMAYLVNLQS DLSKVNNIVK 490 500 510 520 530 540 GVHSGVANVI AADEFEYKDP VDGSVSKHQG IRYMFEDGSR LIFRLSGTGS EGATIRLYIE 550 560 570 580 QYEKDSSKTG RDSQEALKPL VDVALKLSKM QEFSGRSEPT VIT

References

[1]	Michalowski C.B., Quigley-Landreau F., Bohnert H.J. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U84888 mRNA. Translation: AAB41895.1.
PIR	T12574.
3D structure databases
HSSP	HSSP built from PDB template 3PMG based on UniProtKB P00949.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.4.2.2. 2210.
Family and domain databases
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGMC_MESCR

Accession

Primary (citable) accession number: P93262

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	May 1, 1997
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)