Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Annexin

Gene

AnnGh1

Organism
Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi23 – 231Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi25 – 251Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi27 – 271Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi67 – 671Calcium 1Combined sources
Metal bindingi253 – 2531Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi255 – 2551Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi257 – 2571Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi295 – 2951Calcium 3; via carbonyl oxygenCombined sources
Metal bindingi297 – 2971Calcium 2Combined sources
Metal bindingi298 – 2981Calcium 3; via carbonyl oxygenCombined sources
Metal bindingi303 – 3031Calcium 3Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Calcium, Calcium/phospholipid-bindingUniRule annotation, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:AnnGh1Imported
OrganismiGossypium hirsutum (Upland cotton) (Gossypium mexicanum)Imported
Taxonomic identifieri3635 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsMalvalesMalvaceaeMalvoideaeGossypium

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N00X-ray2.10A1-315[»]
3BRXX-ray2.50A1-315[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP93157.

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation
Contains 4 annexin repeats.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR009118. Annexin_pln.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
[Graphical view]
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01814. ANNEXINPLANT.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P93157-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ATLTVPTTVP SVSEDCEQLR KAFSGWGTNE GLIIDILGHR NAEQRNLIRK
60 70 80 90 100
TYAETYGEDL LKALDKELSN DFERLVLLWA LDPAERDALL ANEATKRWTS
110 120 130 140 150
SNQVLMEIAC TRSANQLLHA RQAYHARYKK SLEEDVAHHT TGDFHKLLLP
160 170 180 190 200
LVSSYRYEGE EVNMTLAKTE AKLLHEKISN KAYSDDDVIR VLATRSKAQI
210 220 230 240 250
NATLNHYKNE YGNDINKDLK ADPKDEFLAL LRSTVKCLVY PEKYFEKVLR
260 270 280 290 300
LAINRRGTDE GALTRVVCTR AEVDLKVIAD EYQRRNSVPL TRAIVKDTHG
310
DYEKLLLVLA GHVEN
Length:315
Mass (Da):35,824
Last modified:October 1, 2001 - v2
Checksum:i653113C77AAAE980
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73746 mRNA. Translation: AAB67993.2.
PIRiT10805.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73746 mRNA. Translation: AAB67993.2.
PIRiT10805.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N00X-ray2.10A1-315[»]
3BRXX-ray2.50A1-315[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP93157.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR009118. Annexin_pln.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
[Graphical view]
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01814. ANNEXINPLANT.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structures and functions of annexins in plants."
    Delmer D.P., Potikha T.S.
    Cell. Mol. Life Sci. 53:546-553(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Acala SJ-2Imported.
    Tissue: Cotton fibersImported.
  2. "The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster."
    Hofmann A., Delmer D.P., Wlodawer A.
    Eur. J. Biochem. 270:2557-2564(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
  3. "The crystal structure of calcium-bound annexin Gh1 from Gossypium hirsutum and its implications for membrane binding mechanisms of plant annexins."
    Hu N.J., Yusof A.M., Winter A., Osman A., Reeve A.K., Hofmann A.
    J. Biol. Chem. 283:18314-18322(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) IN COMPLEX WITH CALCIUM.

Entry informationi

Entry nameiP93157_GOSHI
AccessioniPrimary (citable) accession number: P93157
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: October 1, 2001
Last modified: May 11, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.