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P93006

- P2C27_ARATH

UniProt

P93006 - P2C27_ARATH

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Protein

Probable protein phosphatase 2C 27

Gene

At2g33700

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi128 – 1281Manganese 1By similarity
Metal bindingi128 – 1281Manganese 2By similarity
Metal bindingi129 – 1291Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi292 – 2921Manganese 2By similarity
Metal bindingi335 – 3351Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
  2. regulation of transcription from RNA polymerase II promoter in response to salt stress Source: TAIR
  3. response to abscisic acid Source: TAIR
  4. response to cold Source: TAIR
  5. response to salt stress Source: TAIR
  6. response to water deprivation Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT2G33700-MONOMER.
ReactomeiREACT_247278. ISG15 antiviral mechanism.
REACT_259981. Regulation of AMPK activity via LKB1.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 27 (EC:3.1.3.16)
Short name:
AtPP2C27
Gene namesi
Ordered Locus Names:At2g33700
ORF Names:T1B8.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G33700.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: TAIR
  2. nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Probable protein phosphatase 2C 27PRO_0000367956Add
BLAST

Proteomic databases

PaxDbiP93006.
PRIDEiP93006.

Expressioni

Gene expression databases

GenevestigatoriP93006.

Structurei

3D structure databases

ProteinModelPortaliP93006.
SMRiP93006. Positions 72-377.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini83 – 337255PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiP93006.
KOiK14803.
OMAiQRIEIRM.
PhylomeDBiP93006.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P93006-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSMDFSPLLT VLEGDFNKDN TSSATEIDTL ENLDDTRQIS KGKPPRHLTS
60 70 80 90 100
SATRLQLAAN ADVDVCNLVM KSLDDKSEFL PVYRSGSCAE QGAKQFMEDE
110 120 130 140 150
HICIDDLVNH LGAAIQCSSL GAFYGVFDGH GGTDAAHFVR KNILRFIVED
160 170 180 190 200
SSFPLCVKKA IKSAFLKADY EFADDSSLDI SSGTTALTAF IFGRRLIIAN
210 220 230 240 250
AGDCRAVLGR RGRAIELSKD HKPNCTAEKV RIEKLGGVVY DGYLNGQLSV
260 270 280 290 300
ARAIGDWHMK GPKGSACPLS PEPELQETDL SEDDEFLIMG CDGLWDVMSS
310 320 330 340 350
QCAVTIARKE LMIHNDPERC SRELVREALK RNTCDNLTVI VVCFSPDPPQ
360 370 380
RIEIRMQSRV RRSISAEGLN LLKGVLDGYP
Length:380
Mass (Da):41,757
Last modified:May 1, 1997 - v1
Checksum:iB869BEFAE839C550
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78721 Genomic DNA. Translation: AAC69126.1.
CP002685 Genomic DNA. Translation: AEC08870.1.
AY070460 mRNA. Translation: AAL49863.1.
AY091323 mRNA. Translation: AAM14262.1.
PIRiE84748.
RefSeqiNP_180926.1. NM_128928.2.
UniGeneiAt.28645.

Genome annotation databases

EnsemblPlantsiAT2G33700.1; AT2G33700.1; AT2G33700.
GeneIDi817935.
KEGGiath:AT2G33700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78721 Genomic DNA. Translation: AAC69126.1 .
CP002685 Genomic DNA. Translation: AEC08870.1 .
AY070460 mRNA. Translation: AAL49863.1 .
AY091323 mRNA. Translation: AAM14262.1 .
PIRi E84748.
RefSeqi NP_180926.1. NM_128928.2.
UniGenei At.28645.

3D structure databases

ProteinModelPortali P93006.
SMRi P93006. Positions 72-377.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi P93006.
PRIDEi P93006.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G33700.1 ; AT2G33700.1 ; AT2G33700 .
GeneIDi 817935.
KEGGi ath:AT2G33700.

Organism-specific databases

TAIRi AT2G33700.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi P93006.
KOi K14803.
OMAi QRIEIRM.
PhylomeDBi P93006.

Enzyme and pathway databases

BioCyci ARA:AT2G33700-MONOMER.
Reactomei REACT_247278. ISG15 antiviral mechanism.
REACT_259981. Regulation of AMPK activity via LKB1.

Gene expression databases

Genevestigatori P93006.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C27_ARATH
AccessioniPrimary (citable) accession number: P93006
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 1997
Last modified: November 26, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3