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P93006

- P2C27_ARATH

UniProt

P93006 - P2C27_ARATH

Protein

Probable protein phosphatase 2C 27

Gene

At2g33700

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 May 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi128 – 1281Manganese 1By similarity
    Metal bindingi128 – 1281Manganese 2By similarity
    Metal bindingi129 – 1291Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi292 – 2921Manganese 2By similarity
    Metal bindingi335 – 3351Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro
    2. regulation of transcription from RNA polymerase II promoter in response to salt stress Source: TAIR
    3. response to abscisic acid Source: TAIR
    4. response to cold Source: TAIR
    5. response to salt stress Source: TAIR
    6. response to water deprivation Source: TAIR

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT2G33700-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 27 (EC:3.1.3.16)
    Short name:
    AtPP2C27
    Gene namesi
    Ordered Locus Names:At2g33700
    ORF Names:T1B8.2
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G33700.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: TAIR
    2. nucleus Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 380380Probable protein phosphatase 2C 27PRO_0000367956Add
    BLAST

    Proteomic databases

    PaxDbiP93006.
    PRIDEiP93006.

    Expressioni

    Gene expression databases

    GenevestigatoriP93006.

    Structurei

    3D structure databases

    ProteinModelPortaliP93006.
    SMRiP93006. Positions 72-377.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini83 – 337255PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiP93006.
    KOiK14803.
    OMAiQRIEIRM.
    PhylomeDBiP93006.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P93006-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSMDFSPLLT VLEGDFNKDN TSSATEIDTL ENLDDTRQIS KGKPPRHLTS    50
    SATRLQLAAN ADVDVCNLVM KSLDDKSEFL PVYRSGSCAE QGAKQFMEDE 100
    HICIDDLVNH LGAAIQCSSL GAFYGVFDGH GGTDAAHFVR KNILRFIVED 150
    SSFPLCVKKA IKSAFLKADY EFADDSSLDI SSGTTALTAF IFGRRLIIAN 200
    AGDCRAVLGR RGRAIELSKD HKPNCTAEKV RIEKLGGVVY DGYLNGQLSV 250
    ARAIGDWHMK GPKGSACPLS PEPELQETDL SEDDEFLIMG CDGLWDVMSS 300
    QCAVTIARKE LMIHNDPERC SRELVREALK RNTCDNLTVI VVCFSPDPPQ 350
    RIEIRMQSRV RRSISAEGLN LLKGVLDGYP 380
    Length:380
    Mass (Da):41,757
    Last modified:May 1, 1997 - v1
    Checksum:iB869BEFAE839C550
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U78721 Genomic DNA. Translation: AAC69126.1.
    CP002685 Genomic DNA. Translation: AEC08870.1.
    AY070460 mRNA. Translation: AAL49863.1.
    AY091323 mRNA. Translation: AAM14262.1.
    PIRiE84748.
    RefSeqiNP_180926.1. NM_128928.2.
    UniGeneiAt.28645.

    Genome annotation databases

    EnsemblPlantsiAT2G33700.1; AT2G33700.1; AT2G33700.
    GeneIDi817935.
    KEGGiath:AT2G33700.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U78721 Genomic DNA. Translation: AAC69126.1 .
    CP002685 Genomic DNA. Translation: AEC08870.1 .
    AY070460 mRNA. Translation: AAL49863.1 .
    AY091323 mRNA. Translation: AAM14262.1 .
    PIRi E84748.
    RefSeqi NP_180926.1. NM_128928.2.
    UniGenei At.28645.

    3D structure databases

    ProteinModelPortali P93006.
    SMRi P93006. Positions 72-377.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi P93006.
    PRIDEi P93006.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G33700.1 ; AT2G33700.1 ; AT2G33700 .
    GeneIDi 817935.
    KEGGi ath:AT2G33700.

    Organism-specific databases

    TAIRi AT2G33700.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi P93006.
    KOi K14803.
    OMAi QRIEIRM.
    PhylomeDBi P93006.

    Enzyme and pathway databases

    BioCyci ARA:AT2G33700-MONOMER.

    Gene expression databases

    Genevestigatori P93006.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C27_ARATH
    AccessioniPrimary (citable) accession number: P93006
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 1, 1997
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3