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Protein

Probable protein phosphatase 2C 27

Gene

PP2C27

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Confers salt tolerance by triggering the expression of stress-responsive genes.1 Publication

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.PROSITE-ProRule annotation

Cofactori

Mg2+PROSITE-ProRule annotation, Mn2+PROSITE-ProRule annotationNote: Binds 2 magnesium or manganese ions per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi128Manganese 1By similarity1
Metal bindingi128Manganese 2By similarity1
Metal bindingi129Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi292Manganese 2By similarity1
Metal bindingi335Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription from RNA polymerase II promoter in response to salt stress Source: TAIR
  • response to abscisic acid Source: TAIR
  • response to salt stress Source: TAIR
  • response to water deprivation Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 271 Publication (EC:3.1.3.16PROSITE-ProRule annotation)
Short name:
AtPP2C271 Publication
Alternative name(s):
Probable protein phosphatase 2C G group 11 Publication
Short name:
AtPP2CG11 Publication
Gene namesi
Name:PP2C271 Publication
Synonyms:PP2CG11 Publication
Ordered Locus Names:At2g33700Imported
ORF Names:T1B8.2Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G33700
TAIRilocus:2057635 AT2G33700

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Disruption phenotypei

Decreased salt tolerance.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679561 – 380Probable protein phosphatase 2C 27Add BLAST380

Proteomic databases

PaxDbiP93006
PRIDEiP93006

PTM databases

iPTMnetiP93006

Expressioni

Tissue specificityi

Expressed in roots, leaves, stems, flower, and trichomes.1 Publication

Inductioni

Induced in shoots by drought in roots by abscisic acid (ABA), and both in roots and shoot by salt stress.1 Publication

Gene expression databases

ExpressionAtlasiP93006 differential
GenevisibleiP93006 AT

Interactioni

Protein-protein interaction databases

BioGridi3282, 1 interactor
STRINGi3702.AT2G33700.1

Structurei

3D structure databases

ProteinModelPortaliP93006
SMRiP93006
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 344PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST261

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233896
InParanoidiP93006
KOiK14803
OMAiYSKENTS
OrthoDBiEOG09360CMX
PhylomeDBiP93006

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

P93006-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMDFSPLLT VLEGDFNKDN TSSATEIDTL ENLDDTRQIS KGKPPRHLTS
60 70 80 90 100
SATRLQLAAN ADVDVCNLVM KSLDDKSEFL PVYRSGSCAE QGAKQFMEDE
110 120 130 140 150
HICIDDLVNH LGAAIQCSSL GAFYGVFDGH GGTDAAHFVR KNILRFIVED
160 170 180 190 200
SSFPLCVKKA IKSAFLKADY EFADDSSLDI SSGTTALTAF IFGRRLIIAN
210 220 230 240 250
AGDCRAVLGR RGRAIELSKD HKPNCTAEKV RIEKLGGVVY DGYLNGQLSV
260 270 280 290 300
ARAIGDWHMK GPKGSACPLS PEPELQETDL SEDDEFLIMG CDGLWDVMSS
310 320 330 340 350
QCAVTIARKE LMIHNDPERC SRELVREALK RNTCDNLTVI VVCFSPDPPQ
360 370 380
RIEIRMQSRV RRSISAEGLN LLKGVLDGYP
Length:380
Mass (Da):41,757
Last modified:May 1, 1997 - v1
Checksum:iB869BEFAE839C550
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78721 Genomic DNA Translation: AAC69126.1
CP002685 Genomic DNA Translation: AEC08870.1
AY070460 mRNA Translation: AAL49863.1
AY091323 mRNA Translation: AAM14262.1
PIRiE84748
RefSeqiNP_180926.1, NM_128928.3
UniGeneiAt.28645

Genome annotation databases

EnsemblPlantsiAT2G33700.1; AT2G33700.1; AT2G33700
GeneIDi817935
GrameneiAT2G33700.1; AT2G33700.1; AT2G33700
KEGGiath:AT2G33700

Similar proteinsi

Entry informationi

Entry nameiP2C27_ARATH
AccessioniPrimary (citable) accession number: P93006
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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