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Reviewed, UniProtKB/Swiss-Prot P92919 (CB23_APIGR)

Last modified November 24, 2009. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Chlorophyll a-b binding protein, chloroplastic
Alternative name(s):
    Allergen=Api g 3
Gene names
Name: LHC0
OrganismApium graveolens (Celery)
Taxonomic identifier4045 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsasteridscampanulidsApialesApiaceaeApioideaeapioid supercladeApium cladeApium

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.

Cofactor

Binds at least 14 chlorophylls (8 Chl-a and 6 Chl-b) and carotenoids such as lutein and neoxanthin By similarity.

Subunit structure

The LHC complex consists of chlorophyll a-b binding proteins.

Subcellular location

Plastidchloroplast thylakoid membrane; Multi-pass membrane protein.

Domain

The N-terminus of the protein extends into the stroma where it is involved with adhesion of granal membranes and post-translational modifications; both are believed to mediate the distribution of excitation energy between photosystems I and II.

Post-translational modification

Photoregulated by reversible phosphorylation of its threonine residues By similarity.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3535Chloroplast Potential
Chain36 – 264229Chlorophyll a-b binding protein, chloroplastic
PRO_0000003646

Regions

Transmembrane98 – 11821 Potential
Transmembrane150 – 17021 Potential
Transmembrane218 – 23821 Potential

Sites

Metal binding561Magnesium (chlorophyll-b 1 axial ligand); via carbonyl oxygen By similarity
Metal binding971Magnesium (chlorophyll-a 1 axial ligand) By similarity
Metal binding1001Magnesium (chlorophyll-a 2 axial ligand) By similarity
Metal binding1511Magnesium (chlorophyll-b 2 axial ligand); via carbonyl oxygen By similarity
Metal binding1711Magnesium (chlorophyll-b 3 axial ligand) By similarity
Metal binding2121Magnesium (chlorophyll-a 3 axial ligand) By similarity
Metal binding2151Magnesium (chlorophyll-a 4 axial ligand) By similarity
Metal binding2291Magnesium (chlorophyll-a 5 axial ligand) By similarity
Metal binding2441Magnesium (chlorophyll-a 6 axial ligand) By similarity
Binding site781Chlorophyll-a 1; via amide nitrogen By similarity
Binding site841Chlorophyll-a 1 By similarity
Binding site1021Chlorophyll-b 2 By similarity
Binding site1351Chlorophyll-a 3 By similarity
Binding site1451Chlorophyll-a 3; via amide nitrogen By similarity
Binding site1551Chlorophyll-b 3 By similarity
Binding site1631Chlorophyll-b 4 or chlorophyll-b 5 By similarity
Binding site1741Chlorophyll-b 4 By similarity
Binding site1801Chlorophyll-b 2; via amide nitrogen By similarity
Binding site2111Chlorophyll-a 5 By similarity
Binding site2171Chlorophyll-a 1 By similarity
Binding site2531Chlorophyll-a 6; via amide nitrogen By similarity
Binding site2601Chlorophyll-b 5; via carbonyl oxygen By similarity

Amino acid modifications

Modified residue361N2-acetylarginine By similarity
Modified residue381Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
P92919-1 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: 07126C7D5D86BA66

FASTA26428,076
        10         20         30         40         50         60 
MAASTMALSS PALAGKAVKV APSSSELFGN GRVSMRKTVK APVSDSPWYG PDRVKYLGPF 

        70         80         90        100        110        120 
SGEAPSYLTG EFPGDYGWDT AGLSADPETF AKNRELEVIH SRWAMLGALG CVFPELLARN 

       130        140        150        160        170        180 
GVKFGEAVWF KAGSQIFSEG GLDYLGNPSL VHAQSILSIW ATQVILMGAV EGYRVAGGPL 

       190        200        210        220        230        240 
GEIVDPLYPG GSFDPLGLAE DPERSAELKV KELKNGRLAM FSMFGFFVQA IVTGKGPLEN 

       250        260 
LADHLADPVN NNAWAFATNF VPGK 

« Hide

References

[1]"Characterization of a chlorophyll ab binding protein from celery as a food allergen Api g 3."
Hoffmann-Sommergruber K., Pec M., Ferris R., O'Riordain G., Ebner C., Scheiner O., Breiteneder H.
Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Bulb.

Cross-references

Sequence databases

Z75663 mRNA. Translation: CAA99993.1.

3D structure databases

SMRP92919. Positions 46-264.
ModBaseSearch...

Family and domain databases

InterProIPR001344. Chloro_AB_bd.
[Graphical view]
PANTHERPTHR21649. Chloro_AB_bd. 1 hit.
PfamPF00504. Chloroa_b-bind. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCB23_APIGR
AccessionPrimary (citable) accession number: P92919
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: May 1, 1997
Last modified: November 24, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Allergens

Nomenclature of allergens and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents