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P92039

- P92039_HAECO

UniProt

P92039 - P92039_HAECO

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Protein
Submitted name: Acetylcholine receptor alpha subunit
Gene
AChR
Organism
Haemonchus contortus (Barber pole worm)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. acetylcholine-activated cation-selective channel activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotations, ReceptorSAAS annotationsImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Acetylcholine receptor alpha subunitImported
Gene namesi
Name:AChRImported
OrganismiHaemonchus contortus (Barber pole worm)Imported
Taxonomic identifieri6289 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaStrongylidaTrichostrongyloideaHaemonchidaeHaemonchinaeHaemonchus

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
  3. postsynaptic membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotations, Membrane, Postsynaptic cell membraneSAAS annotations, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 PredictedImported
Add
BLAST
Chaini20 – 512493acetylcholine receptor alpha subunitImported
PRO_5000145150Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliP92039.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

SignalImported, Transmembrane, Transmembrane helixSAAS annotations

Family and domain databases

Gene3Di1.20.120.370. 2 hits.
2.70.170.10. 1 hit.
InterProiIPR027361. Acetylcholine_rcpt_TM.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P92039-1 [UniParc]FASTAAdd to Basket

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MRHLLSFVIS FVSFYYIYAN EDAKRLYDDL MVNYNRHRRP ASGPHEPLTI    50
KLKLRLSQII DVHEIDQIMT CSVWLKQVWI DKKLSWDPES YGGVSVLYVP 100
YEMIWVPDIV LYNNADSNYN ITISTKATLH YSGEVTWEPP AIFKSMCQID 150
VRWFPFDEQQ CHLKFGSWTN SENLLNLELL ENNVRYEEEV NEQGIVDNIT 200
IADDGIDLSD YYPSVEWDIM SRVARRRSKN YPSCCPQSAY IDIMYYLELR 250
RKPLFYTVNL VFPCVGISFL TILVFYLPSD SGEKVTLCIS ILVALTIFFL 300
LLTEIIPATS ITLPLIGKYL LFTMVMVTLS VVVTVISLNL HFRTPTTHLM 350
PKWVKLVFLK WLPKVLFMRR PLDDGDESFR RVSSRKGIGP TTFDGKIPLN 400
LHEHRVSRDI GKSLANAAID ERIQKLYYSP QVVKAFENIC FIAELLKKKD 450
RDDKIDEDWK YVAMVLDRLF LLIFSFACFI GTVLILLQAP TLYDDRKPID 500
LQYRPANLSA LF 512
Length:512
Mass (Da):59,540
Last modified:May 1, 1997 - v1
Checksum:iCABE7A264200DB03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U72490 mRNA. Translation: AAB51667.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U72490 mRNA. Translation: AAB51667.1 .

3D structure databases

ProteinModelPortali P92039.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.120.370. 2 hits.
2.70.170.10. 1 hit.
InterProi IPR027361. Acetylcholine_rcpt_TM.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
[Graphical view ]
PANTHERi PTHR18945. PTHR18945. 1 hit.
Pfami PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view ]
PRINTSi PR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMi SSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsi TIGR00860. LIC. 1 hit.
PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Hoekstra R.R.
    Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Characterization of an acetylcholine receptor gene of Haemonchus contortus in relation to levamisole resistance."
    Hoekstra R., Visser A., Wiley L.J., Weiss A.S., Sangster N.C., Roos M.H.
    Mol. Biochem. Parasitol. 84:179-187(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP92039_HAECO
AccessioniPrimary (citable) accession number: P92039
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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