P92039 (P92039_HAECO) Unreviewed, UniProtKB/TrEMBL
Last modified
April 3, 2013.
Version 75.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: Acetylcholine receptor alpha subunit EMBL AAB51667.1 | ||
| Gene names |
| ||
| Organism | Haemonchus contortus (Barber pole worm) EMBL AAB51667.1 | ||
| Taxonomic identifier | 6289 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Strongylida › Trichostrongyloidea › Haemonchidae › Haemonchinae › Haemonchus![]() |
Protein attributes
| Sequence length | 512 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Sequence similarities | Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Ion transport Transport |
| Cellular component | Cell junction Cell membrane SAAS SAAS006202 Membrane Postsynaptic cell membrane SAAS SAAS006202 Synapse |
| Domain | Signal EMBL AAB51667.1 Transmembrane Transmembrane helix SAAS SAAS006202 |
| Molecular function | Ion channel Ligand-gated ion channel SAAS SAAS006202 Receptor SAAS SAAS006202 EMBL AAB51667.1 |
| PTM | Disulfide bond SAAS SAAS006202 |
| Gene Ontology (GO) | |
| Cellular_component | cell junction Inferred from electronic annotation. Source: UniProtKB-KW integral to membraneInferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-KW postsynaptic membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | acetylcholine-activated cation-selective channel activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||
Molecule processing | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 19 | 19 | Potential EMBL AAB51667.1 | |||||
| Chain | 20 – 512 | 493 | acetylcholine receptor alpha subunit EMBL AAB51667.1 | PRO_5000145150 | ||||
Sequences
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References
| [1] | Hoekstra R.R. Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [2] | "Characterization of an acetylcholine receptor gene of Haemonchus contortus in relation to levamisole resistance." Hoekstra R., Visser A., Wiley L.J., Weiss A.S., Sangster N.C., Roos M.H. Mol. Biochem. Parasitol. 84:179-187(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U72490 mRNA. Translation: AAB51667.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1OED based on UniProtKB P02711. |
| ProteinModelPortal | P92039. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| Gene3D | 2.70.170.10. 1 hit. |
| InterPro | IPR006202. Neur_chan_lig-bd. IPR006201. Neur_channel. IPR006029. Neurotrans-gated_channel_TM. IPR018000. Neurotransmitter_ion_chnl_CS. IPR002394. Nicotinic_acetylcholine_rcpt. [Graphical view] |
| PANTHER | PTHR18945. PTHR18945. 1 hit. |
| Pfam | PF02931. Neur_chan_LBD. 1 hit. PF02932. Neur_chan_memb. 1 hit. [Graphical view] |
| PRINTS | PR00254. NICOTINICR. PR00252. NRIONCHANNEL. |
| SUPFAM | SSF90112. Neu_channel_TM. 1 hit. SSF63712. Neur_chan_LBD. 1 hit. |
| TIGRFAMs | TIGR00860. LIC. 1 hit. |
| PROSITE | PS00236. NEUROTR_ION_CHANNEL. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | P92039_HAECO | ||||||||
| Accession | Primary (citable) accession number: P92039 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
