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Protein

60S acidic ribosomal protein P1

Gene

rla-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the elongation step of protein synthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P1
Alternative name(s):
Ribosomal protein large subunit P1
Gene namesi
Name:rla-1
Synonyms:rpa-1
ORF Names:Y37E3.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiY37E3.7; CE26658; WBGene00004409; rla-1.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001576901 – 11160S acidic ribosomal protein P1Add BLAST111

Proteomic databases

EPDiP91913.
PaxDbiP91913.
PeptideAtlasiP91913.
PRIDEiP91913.

Expressioni

Gene expression databases

BgeeiWBGene00004409.

Interactioni

Subunit structurei

P1 and P2 exist as dimers at the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi37253. 2 interactors.
IntActiP91913. 3 interactors.
MINTiMINT-1053900.
STRINGi6239.Y37E3.7.1.

Structurei

3D structure databases

ProteinModelPortaliP91913.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1762. Eukaryota.
COG2058. LUCA.
GeneTreeiENSGT00550000074698.
HOGENOMiHOG000229898.
InParanoidiP91913.
KOiK02942.
OMAiQELLCTY.
OrthoDBiEOG093706K6.
PhylomeDBiP91913.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch. 1 hit.
InterProiView protein in InterPro
IPR027534. Ribosomal_L12.
IPR001859. T.cruzi_P2-like.
PRINTSiPR00456. RIBOSOMALP2.

Sequencei

Sequence statusi: Complete.

P91913-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNQELACV YAALILQDDE VAITGEKIAT LLKAANVEFE PYWPGLFAKA
60 70 80 90 100
LEGVDVKNLI TSVSSGAGSG PAPAAAAAAP AAGGAAPAAE TKKKEEPKEE
110
SDDDMGFGLF D
Length:111
Mass (Da):11,284
Last modified:June 20, 2002 - v2
Checksum:i6DB5B65BACFCC4A6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti42Y → N in AAB48625 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89307 mRNA. Translation: AAB48625.1.
FO081769 Genomic DNA. Translation: CCD73427.1.
RefSeqiNP_740801.1. NM_170818.4.
UniGeneiCel.23209.

Genome annotation databases

EnsemblMetazoaiY37E3.7.1; Y37E3.7.1; WBGene00004409.
Y37E3.7.2; Y37E3.7.2; WBGene00004409.
GeneIDi171766.
KEGGicel:CELE_Y37E3.7.
UCSCiF18A1.5. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRLA1_CAEEL
AccessioniPrimary (citable) accession number: P91913
Secondary accession number(s): Q9GR59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: June 20, 2002
Last modified: June 7, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families