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Protein

Bombyxin F-1

Gene

BBXF1

Organism
Bombyx mori (Silk moth)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Keywords - Molecular functioni

Hormone

Names & Taxonomyi

Protein namesi
Recommended name:
Bombyxin F-1
Short name:
BBX-F1
Cleaved into the following 2 chains:
Gene namesi
Name:BBXF1
OrganismiBombyx mori (Silk moth)
Taxonomic identifieri7091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
Proteomesi
  • UP000005204 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Peptidei20 – 5031Bombyxin F-1 B chainPRO_0000016037Add
BLAST
Propeptidei53 – 7119C peptide likePRO_0000016038Add
BLAST
Peptidei76 – 9520Bombyxin F-1 A chainPRO_0000016039Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi29 ↔ 82Interchain (between B and A chains)By similarity
Disulfide bondi41 ↔ 95Interchain (between B and A chains)By similarity
Disulfide bondi81 ↔ 86By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Interactioni

Subunit structurei

Heterodimer of a B chain and an A chain linked by two disulfide bonds.By similarity

Structurei

3D structure databases

ProteinModelPortaliP91896.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the insulin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiP91896.
KOiK04526.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR017097. Bombyxin.
IPR016179. Insulin-like.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PIRSFiPIRSF037038. Bombyxin. 1 hit.
PRINTSiPR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P91896-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVVIVLLV ISVSILVSAQ ELGGSRRYCG RHLAQTMAVL CWGIDEMSAE
60 70 80 90
KRNSDMVYED SGMPELLPAD TRKKRGIIDE CCLQACTRDV LLSYC
Length:95
Mass (Da):10,567
Last modified:December 1, 2000 - v2
Checksum:i5EF960C1322707CC
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti71 – 711T → A in strain: Showa.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001049 Genomic DNA. Translation: BAA19223.1.
AB001050 Genomic DNA. Translation: BAA19224.1.
RefSeqiNP_001119734.1. NM_001126262.1.
UniGeneiBmo.10600.

Genome annotation databases

GeneIDi100146110.
KEGGibmor:100146110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001049 Genomic DNA. Translation: BAA19223.1.
AB001050 Genomic DNA. Translation: BAA19224.1.
RefSeqiNP_001119734.1. NM_001126262.1.
UniGeneiBmo.10600.

3D structure databases

ProteinModelPortaliP91896.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100146110.
KEGGibmor:100146110.

Organism-specific databases

CTDi100146110.

Phylogenomic databases

InParanoidiP91896.
KOiK04526.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR017097. Bombyxin.
IPR016179. Insulin-like.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PIRSFiPIRSF037038. Bombyxin. 1 hit.
PRINTSiPR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBXF1_BOMMO
AccessioniPrimary (citable) accession number: P91896
Secondary accession number(s): P91897
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: March 16, 2016
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.