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Protein
Submitted name:

RAB family

Gene

rab-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activating protein binding Source: WormBase
  • GTPase activity Source: WormBase
  • GTP binding Source: InterPro

GO - Biological processi

  • apical protein localization Source: WormBase
  • embryo development ending in birth or egg hatching Source: WormBase
  • phagosome maturation involved in apoptotic cell clearance Source: WormBase
  • protein localization Source: WormBase
  • protein secretion Source: WormBase
  • receptor-mediated endocytosis Source: WormBase
  • regulation of endocytosis Source: GO_Central

Enzyme and pathway databases

ReactomeiR-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-6798695 Neutrophil degranulation
R-CEL-8854214 TBC/RABGAPs
R-CEL-8856828 Clathrin-mediated endocytosis
R-CEL-8873719 RAB geranylgeranylation
R-CEL-8876198 RAB GEFs exchange GTP for GDP on RABs
R-CEL-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyi

Protein namesi
Submitted name:
RAB familyImported
Gene namesi
Name:rab-5Imported
ORF Names:CELE_F26H9.6Imported, F26H9.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF26H9.6 ; CE09711 ; WBGene00004268 ; rab-5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiP91857
PaxDbiP91857

Expressioni

Gene expression databases

BgeeiWBGene00004268
ExpressionAtlasiP91857 baseline and differential

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • GTPase activating protein binding Source: WormBase

Protein-protein interaction databases

IntActiP91857, 5 interactors
MINTiP91857
STRINGi6239.F26H9.6.1

Structurei

3D structure databases

ProteinModelPortaliP91857
SMRiP91857
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0092 Eukaryota
ENOG410YCCP LUCA
GeneTreeiENSGT00760000119101
HOGENOMiHOG000233968
InParanoidiP91857
KOiK07888
OMAiLIKAKHW
OrthoDBiEOG091G0HKN
PhylomeDBiP91857

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequencei

Sequence statusi: Complete.

P91857-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARNAGTAR PGGPNRTCQF KLVLLGESAV GKSSLVLRFV KGQFHEYQES
60 70 80 90 100
TIGAAFLTQT VCLDDATIKF EIWDTAGQER YHSLAPMYYR GAQAAIVVYD
110 120 130 140 150
ITNQESFQKA KNWVKELQRQ ASPNIVMALA GNKADVANKR TVEYEEANAY
160 170 180 190 200
AEDNALLFME TSAKTSMNVN DIFMAIAKKL PIGPAQGEPT GTVDMNQPQQ

QQKGSCCK
Length:208
Mass (Da):22,836
Last modified:May 1, 1997 - v1
Checksum:i3DCD9DA1716AB992
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB04205.1
PIRiT21442
RefSeqiNP_492481.1, NM_060080.3
UniGeneiCel.17365

Genome annotation databases

EnsemblMetazoaiF26H9.6; F26H9.6; WBGene00004268
GeneIDi172755
KEGGicel:CELE_F26H9.6
UCSCiF26H9.6.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiP91857_CAEEL
AccessioniPrimary (citable) accession number: P91857
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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