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Protein
Submitted name:

Cysteine protease

Gene
N/A
Organism
Onchocerca volvulus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, ProteaseImported

Protein family/group databases

MEROPSiC01.087.

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine proteaseImported
OrganismiOnchocerca volvulusImported
Taxonomic identifieri6282 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeOnchocerca

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20UniRule annotationAdd BLAST20
ChainiPRO_500539993621 – 306UniRule annotationAdd BLAST286

Structurei

3D structure databases

ProteinModelPortaliP91771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 303Pept_C1InterPro annotationAdd BLAST238

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR033157. Cathepsin_X.
IPR025661. Pept_asp_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
PANTHERiPTHR12411. PTHR12411. 1 hit.
PTHR12411:SF432. PTHR12411:SF432. 1 hit.
PfamiView protein in Pfam
PF00112. Peptidase_C1. 1 hit.
SMARTiView protein in SMART
SM00645. Pept_C1. 1 hit.
PROSITEiView protein in PROSITE
PS00640. THIOL_PROTEASE_ASN. 1 hit.

Sequencei

Sequence statusi: Complete.

P91771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAILFNFFL LTYFTNITLG KVGKSIDLDT RNGYNVHGCY KQTGKIYAHK
60 70 80 90 100
TYPRQYEAEN YNFDDLPVAW DWRNINGVNY ASVDRNQHIP QYCGSCWAFG
110 120 130 140 150
STSALADRFN IKRKGAWPPA YLSVQEVIDC ANAGSCEGGE PGPVYKYAHE
160 170 180 190 200
FGIPHETCNN YQARDGTCSS YNKCGSCWPG SCFSIKNYTI YRVKNYGAVS
210 220 230 240 250
GLHKMKAEIY HHGPIACGIA ATKAFETYAG GIYNERTNED IDHIISVHGW
260 270 280 290 300
GVDSESGVPY WIGRNSWGTP WGENGWFRIV TSEYKNSSSK YNLKIEEDCV

WADPIA
Length:306
Mass (Da):34,452
Last modified:May 1, 1997 - v1
Checksum:i8AF4E4EAD1FB1916
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U71150 mRNA. Translation: AAC47348.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiP91771_ONCVO
AccessioniPrimary (citable) accession number: P91771
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: February 15, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)