P91759 (ALF_LYMST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Fructose-bisphosphate aldolase EC=4.1.2.13
Organism	Lymnaea stagnalis (Great pond snail)
Taxonomic identifier	6523 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Gastropoda › Heterobranchia › Euthyneura › Panpulmonata › Hygrophila › Lymnaeoidea › Lymnaeidae › Lymnaea

Protein attributes

Sequence length	101 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
Sequence similarities	Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
Biological process	Glycolysis
Ligand	Schiff base
Molecular function	Lyase
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›101	›101	Fructose-bisphosphate aldolase		PRO_0000216932
Sites
	Active site	11	1	Schiff-base intermediate with dihydroxyacetone-P By similarity
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	101	1

Sequences

	Sequence		Length	Mass (Da)
	P91759 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: A151A6471A6AAFBD	FASTA	101	10,831
	10 20 30 40 50 60 HNMFLEGTLL KPNMVTAGQG CPKKYTPEDI ARATVTALNR TVPAAVAGIT FLSGGQSEED 70 80 90 100 ATINLNAINQ FPGRKPWPLT FSYGRALQAS VLKAWGGKDE L

References

[1]	Fainzilber M., Kesteren R.E., Smit A.B. Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	U73114 mRNA. Translation: AAC47398.1.
3D structure databases
ProteinModelPortal	P91759.
SMR	P91759. Positions 1-100.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00109; UER00183.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. [Graphical view]
PANTHER	PTHR11627. PTHR11627. 1 hit.
Pfam	PF00274. Glycolytic. 1 hit. [Graphical view]
PROSITE	PS00158. ALDOLASE_CLASS_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALF_LYMST

Accession

Primary (citable) accession number: P91759

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1997
Last modified:	March 6, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)