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P91745

- PE48A_LUCCU

UniProt

P91745 - PE48A_LUCCU

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Protein
Peritrophin-48
Gene
N/A
Organism
Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

May bind chitin or related oligosaccharide structures.1 Publication

GO - Molecular functioni

  1. chitin binding Source: UniProtKB

GO - Biological processi

  1. chitin metabolic process Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Chitin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peritrophin-48
OrganismiLucilia cuprina (Green bottle fly) (Australian sheep blowfly)
Taxonomic identifieri7375 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaCalliphoridaeLuciliinaeLucilia

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20202 Publications
Add
BLAST
Chaini21 – 375355Peritrophin-481 Publication
PRO_0000023615Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi60 ↔ 73 By similarity
Glycosylationi117 – 1171N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi120 ↔ 133 By similarity
Disulfide bondi187 ↔ 200 By similarity
Disulfide bondi265 ↔ 278 By similarity
Disulfide bondi330 ↔ 343 By similarity
Glycosylationi360 – 3601N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

Glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Expressioni

Tissue specificityi

Cardia and midgut peritrophic membrane.1 Publication

Developmental stagei

Expressed in all 3 larval instars and adults, but not pupae or eggs.

Structurei

3D structure databases

ProteinModelPortaliP91745.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 8359Chitin-binding type-2 1
Add
BLAST
Domaini86 – 14358Chitin-binding type-2 2
Add
BLAST
Domaini153 – 21058Chitin-binding type-2 3
Add
BLAST
Domaini224 – 29269Chitin-binding type-2 4
Add
BLAST
Domaini294 – 36067Chitin-binding type-2 5
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di2.170.140.10. 4 hits.
InterProiIPR002557. Chitin-bd_dom.
[Graphical view]
PfamiPF01607. CBM_14. 5 hits.
[Graphical view]
SMARTiSM00494. ChtBD2. 5 hits.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 4 hits.
PROSITEiPS50940. CHIT_BIND_II. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P91745-1 [UniParc]FASTAAdd to Basket

« Hide

MIIKTLLASV AIMLIATVNA EYNVAKYCEL VKIGTLMPSM ISCQDYYICR    50
LNNQPIPVKC GANTVFDKDT QGCVPEAQAN CILSLDNPCE NKDRTFAPSS 100
KACNEWHYCL NGNIVANGSC QPGQIFDASK NSCIYGACNS DDDDSNSDFT 150
PVLNICDIMQ NGQFFGDFEN CQNWQKCNNG RLQKGICLGN LVYDTKNGMC 200
LQNDGTMCER TNGMVSEDGG APDETLCTSS NDGPLPDKLT CSVYYICEQD 250
TTSTPTTYKW IKTSCPNGQY FDVFGDGCLD RAKRRVYTGC NRCEYTTGST 300
TYWVNAVSND CTKFSTCRNG RKITNEDGSC NSGYYFNEAD QYCNMGDFTN 350
YAETNGACQN YSCNGYDCTT KPSAT 375
Length:375
Mass (Da):41,318
Last modified:May 1, 1997 - v1
Checksum:i459082BF0AF6C7AF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U79715 mRNA. Translation: AAB38414.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U79715 mRNA. Translation: AAB38414.1 .

3D structure databases

ProteinModelPortali P91745.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.170.140.10. 4 hits.
InterProi IPR002557. Chitin-bd_dom.
[Graphical view ]
Pfami PF01607. CBM_14. 5 hits.
[Graphical view ]
SMARTi SM00494. ChtBD2. 5 hits.
[Graphical view ]
SUPFAMi SSF57625. SSF57625. 4 hits.
PROSITEi PS50940. CHIT_BIND_II. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "cDNA and deduced amino acid sequences of a peritrophic membrane glycoprotein, 'peritrophin-48', from the larvae of Lucilia cuprina."
    Schorderet S., Pearson R.D., Vuocolo T., Eisemann C.H., Riding G.A., Tellam R.L.
    Insect Biochem. Mol. Biol. 28:99-111(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 21-47; 60-68; 93-101; 185-196 AND 239-256, TISSUE SPECIFICITY.
    Tissue: Larval peritrophic membrane.
  2. "Characterization of a major peritrophic membrane protein, peritrophin-44, from the larvae of Lucilia cuprina. cDNA and deduced amino acid sequences."
    Elvin C.M., Vuocolo T., Pearson R.D., East I.J., Riding G.A., Eisemann C.H., Tellam R.L.
    J. Biol. Chem. 271:8925-8935(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 21-49.
    Tissue: Larval peritrophic membrane.

Entry informationi

Entry nameiPE48A_LUCCU
AccessioniPrimary (citable) accession number: P91745
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: May 1, 1997
Last modified: October 16, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3