FGF homolog - Drosophila melanogaster (Fruit fly)

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Unreviewed, UniProtKB/TrEMBL P91672 (P91672_DROME)

Last modified June 16, 2009. Version 53. History...

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
FGF homolog EMBL AAC47427.1

Gene names

Name:	bnl FlyBase FBgn0014135
Synonyms:	branchless EMBL AAC47427.1
ORF Names:	CG4608 FlyBase FBgn0014135

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAC47427.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	770 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cytoneme assembly Inferred from direct assay. Source: FlyBase epithelial cell migration, open tracheal system Traceable author statement. Source: FlyBase fibroblast growth factor receptor signaling pathway Non-traceable author statement. Source: FlyBase filopodium assembly Inferred from mutant phenotype. Source: FlyBase genital disc development Inferred from expression pattern. Source: FlyBase positive chemotaxis Traceable author statement. Source: FlyBase primary branching, open tracheal system Traceable author statement. Source: FlyBase regulation of tube architecture, open tracheal system Traceable author statement. Source: FlyBase secondary branching, open tracheal system Traceable author statement. Source: FlyBase terminal branching, open tracheal system Traceable author statement. Source: FlyBase tracheal outgrowth, open tracheal system Traceable author statement. Source: FlyBase
Molecular function	fibroblast growth factor receptor binding Traceable author statement. Source: FlyBase growth factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

P91672-1 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: 981FAD251B6E0F93
Show »

770

84,113

        10         20         30         40         50         60 
MRRNLRLDWR ALALLGALLS FIIAWRGLVS AMPLMAMDNN LTDSSGSTNT STSSTSKYNS 

        70         80         90        100        110        120 
TNNSNLFSNS YLQSDHSRSS LVPSAVSERS VNQPTNQSIN AEFNQSLSTH PTAITSTPQT 

       130        140        150        160        170        180 
QTQTQIQSQY PSQAEDSDQL EEPLGFVISA MPNEHLAVLS RTERSIRHQN QQQQKKHHHH 

       190        200        210        220        230        240 
HQQQQQQQHQ QQQPMSPADN NFIGSKSKRL SNPRSSLNIN SSSSNTPISN LDRNERSTVP 

       250        260        270        280        290        300 
QSHLAWTSRK IQLYIKNRIL QILRDGVVNG TQDENSEFTI LQRSTVDVGR IKLQSVATCL 

       310        320        330        340        350        360 
YLCMDACGVP YGSKDFTDDC VFNENMGLQN YNTYSSTYHS QARRVFYLAL NGSGQPRRTQ 

       370        380        390        400        410        420 
IPASRSLGKL STYTNAITET VPQERVEQLI AKNFGANRVK HGVRQLCDTG KPLIELIDVA 

       430        440        450        460        470        480 
RFKAPPHCSS NTSGSSSSIS SSSSSSSKSS SNSSSSYVPV SAISSLSSIS NSSQSESGHI 

       490        500        510        520        530        540 
SSSLSGTSNS NSSSNSSSSN SSSNSSRPSG SKANKKKKPK CKPHEQEDTH NCQKRGGAGA 

       550        560        570        580        590        600 
GALRKLGPKA KRCKELREKA AAEKRAPPNC GKKNGARKNP TEAAKAVQQR PKGNIQHGGK 

       610        620        630        640        650        660 
KKPNKAGKQR QNGGKKQQQQ QQHQLQQQPL QHQAKSISGG KRKHRKLDAS TTTTMATSLG 

       670        680        690        700        710        720 
TPPSSHWESS SPLPAFSLSE TSDRVERNVR MSSGEEQDQD NDQDQEQSDP GEQGEEETEG 

       730        740        750        760        770 
DGGSLEDASY EDSSSEAQGR SGAGGDDSLY YDFLCLQLIA MVLLRKRAIL

References

[1]	"branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching." Sutherland D., Samakovlis C., Krasnow M.A. Cell 87:1091-1101(1996) [PubMed: 8978613] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Sutherland D.C., Samakovlis C., Krasnow M.A. Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	U82273 mRNA. Translation: AAC47427.1.
3D structure databases
HSSP	HSSP built from PDB template 4FGF based on UniProtKB P09038.
ModBase	Search...
Protein-protein interaction databases
IntAct	P91672. 1 interaction.
Proteomic databases
PRIDE	P91672.
Genome annotation databases
Ensembl	FBgn0014135. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0014135. bnl.
Phylogenomic databases
HOGENOM	P91672.
Gene expression databases
ArrayExpress	P91672.
Family and domain databases
InterPro	IPR002209. GF_heparin_bd. IPR002348. IL1_HBGF. [Graphical view]
PANTHER	PTHR11486. IL1_HBGF. 1 hit.
Pfam	PF00167. FGF. 1 hit. [Graphical view]
PRINTS	PR00263. HBGFFGF.
ProDom	PD000831. IL1_HBGF. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00442. FGF. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P91672_DROME

Accession

Primary (citable) accession number: P91672

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	June 16, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information