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Protein
Submitted name:

Transglutiminase

Gene

tgm2

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei348UniRule annotation1
Active sitei406UniRule annotation1
Active sitei429UniRule annotation1
Metal bindingi469CalciumUniRule annotation1
Metal bindingi471CalciumUniRule annotation1
Metal bindingi519CalciumUniRule annotation1
Metal bindingi524CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TransglutiminaseImported
Gene namesi
Name:tgm2Imported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Structurei

3D structure databases

ProteinModelPortaliP91590
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini340 – 432TGcInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
HOGENOMiHOG000231695
KOiK05625

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit

Sequencei

Sequence statusi: Complete.

P91590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRFRRRWFV IDAENAEEVN EFLDEHPRFL GEYIDRNPHL LDNYVIDNVD
60 70 80 90 100
EETIQKWLDK VSGPAPTEVL QILRVNYKKE TNCVDHHTDK YIHNSLVVRR
110 120 130 140 150
ATTFDLGLVF KNRNYRPAKD DIVLEFTIGS DPTIKNETKI RVPVGDSLQG
160 170 180 190 200
SKWTCMKINE DEVTKEVTLQ VNIPPDAIIG RYKLTVEVAT ELKDGRQKER
210 220 230 240 250
KVKPDIVVLF NPFKPADPVY MESSVEREEY VLNDTGRIYV GQWYRIGAKD
260 270 280 290 300
WLFGQFEEGI LDIALKLLRE HTNAQKNATK SLKKRASPAY CSRLLSAMVN
310 320 330 340 350
CNDDNGVLWG RWDGKYEEGV KPTTWSGSVA ILKQWNRTKM NPVKYGQCWV
360 370 380 390 400
FSGLLTTVLR ALGIPARSIT NFNSAHDTEY NMTIDKFLTE DGESAEGTGD
410 420 430 440 450
SIWNFHVWNE GFFRRPDLPK GYDGWQAVDA TPQEESSGVM QCGPAPIKAI
460 470 480 490 500
KNGEIYIGSD TNFVFAEVNA DRVFWEVNDE GEVTKMVKND KRHVGRNIST
510 520 530 540 550
KAVGSDERED VTLQYKFAEG SEEERVAFER AYAHGRKAPY HDKFVLEDEG
560 570 580 590 600
NIKIDINPVG DVINGSDVSI SVKVTNAKGV DCDATITTVI HTMLNNEERK
610 620 630 640 650
RLLKRSRGTR KIAAGKDDVE SFKFGFGDYG RHLSDENVIR VTTTVRVKET
660 670 680 690 700
NKLYVDQYDI QIESPQCLEL ICADELKVRE YQPIRFKITN PLKVAMTSAV
710 720 730 740 750
FSLQGSGISS GKSFEVPSPI EPGETYTSPE MEVRPYRSSR ATTILGDFDC
760
NEIWNIKARK RVAVNF
Length:766
Mass (Da):87,194
Last modified:November 1, 1998 - v2
Checksum:i7F90D921D87FDD1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10212 mRNA Translation: CAA71263.1
RefSeqiNP_001027712.1, NM_001032540.1
UniGeneiCin.22973

Genome annotation databases

GeneIDi445739
KEGGicin:445739

Similar proteinsi

Entry informationi

Entry nameiP91590_CIOIN
AccessioniPrimary (citable) accession number: P91590
Secondary accession number(s): A0A1W2VNA7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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