P91590 (P91590_CIOIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Transglutiminase EMBL CAA71263.1
Organism	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) EMBL CAA71263.1
Taxonomic identifier	7719 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona

Protein attributes

Sequence length	766 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor

Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Gene Ontology (GO)
Biological_process	peptide cross-linking Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	348	1	By similarity PIRSR PIRSR000459-1
	Active site	406	1	By similarity PIRSR PIRSR000459-1
	Active site	429	1	By similarity PIRSR PIRSR000459-1
	Metal binding	469	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	471	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	519	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	524	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	P91590 [UniParc]. Last modified November 1, 1998. Version 2. Checksum: 7F90D921D87FDD1D	FASTA	766	87,194
	10 20 30 40 50 60 MSRFRRRWFV IDAENAEEVN EFLDEHPRFL GEYIDRNPHL LDNYVIDNVD EETIQKWLDK 70 80 90 100 110 120 VSGPAPTEVL QILRVNYKKE TNCVDHHTDK YIHNSLVVRR ATTFDLGLVF KNRNYRPAKD 130 140 150 160 170 180 DIVLEFTIGS DPTIKNETKI RVPVGDSLQG SKWTCMKINE DEVTKEVTLQ VNIPPDAIIG 190 200 210 220 230 240 RYKLTVEVAT ELKDGRQKER KVKPDIVVLF NPFKPADPVY MESSVEREEY VLNDTGRIYV 250 260 270 280 290 300 GQWYRIGAKD WLFGQFEEGI LDIALKLLRE HTNAQKNATK SLKKRASPAY CSRLLSAMVN 310 320 330 340 350 360 CNDDNGVLWG RWDGKYEEGV KPTTWSGSVA ILKQWNRTKM NPVKYGQCWV FSGLLTTVLR 370 380 390 400 410 420 ALGIPARSIT NFNSAHDTEY NMTIDKFLTE DGESAEGTGD SIWNFHVWNE GFFRRPDLPK 430 440 450 460 470 480 GYDGWQAVDA TPQEESSGVM QCGPAPIKAI KNGEIYIGSD TNFVFAEVNA DRVFWEVNDE 490 500 510 520 530 540 GEVTKMVKND KRHVGRNIST KAVGSDERED VTLQYKFAEG SEEERVAFER AYAHGRKAPY 550 560 570 580 590 600 HDKFVLEDEG NIKIDINPVG DVINGSDVSI SVKVTNAKGV DCDATITTVI HTMLNNEERK 610 620 630 640 650 660 RLLKRSRGTR KIAAGKDDVE SFKFGFGDYG RHLSDENVIR VTTTVRVKET NKLYVDQYDI 670 680 690 700 710 720 QIESPQCLEL ICADELKVRE YQPIRFKITN PLKVAMTSAV FSLQGSGISS GKSFEVPSPI 730 740 750 760 EPGETYTSPE MEVRPYRSSR ATTILGDFDC NEIWNIKARK RVAVNF

References

[1]	"A new transglutaminase-like from the ascidian Ciona intestinalis." Cariello L., Ristoratore F., Zanetti L. FEBS Lett. 408:171-176(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Cariello L. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y10212 mRNA. Translation: CAA71263.1.
RefSeq	NP_001027712.1. NM_001032540.1.
UniGene	Cin.22973.
3D structure databases
HSSP	HSSP built from PDB template 1KV3 based on UniProtKB P21980.
ProteinModelPortal	P91590.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	445739.
KEGG	cin:445739.
Organism-specific databases
CTD	7052.
Phylogenomic databases
eggNOG	NOG80379.
HOGENOM	HOG000231695.
InParanoid	P91590.
KO	K05625.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
ProtoNet	Search...

Entry information

Entry name

P91590_CIOIN

Accession

Primary (citable) accession number: P91590

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	November 1, 1998
Last modified:	April 3, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)