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P91590

- P91590_CIOIN

UniProt

P91590 - P91590_CIOIN

Protein
Submitted name:

Transglutiminase

Gene
N/A
Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 2 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei348 – 3481UniRule annotation
    Active sitei348 – 3481 By similarity
    Active sitei406 – 4061UniRule annotation
    Active sitei406 – 4061 By similarity
    Active sitei429 – 4291UniRule annotation
    Metal bindingi469 – 4691Calcium
    Metal bindingi471 – 4711Calcium
    Metal bindingi519 – 5191Calcium
    Metal bindingi524 – 5241Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    TransglutiminaseImported
    OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
    Taxonomic identifieri7719 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

    Interactioni

    Protein-protein interaction databases

    STRINGi7719.ENSCINP00000000870.

    Structurei

    3D structure databases

    ProteinModelPortaliP91590.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG80379.
    HOGENOMiHOG000231695.
    InParanoidiP91590.
    KOiK05625.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P91590-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSRFRRRWFV IDAENAEEVN EFLDEHPRFL GEYIDRNPHL LDNYVIDNVD    50
    EETIQKWLDK VSGPAPTEVL QILRVNYKKE TNCVDHHTDK YIHNSLVVRR 100
    ATTFDLGLVF KNRNYRPAKD DIVLEFTIGS DPTIKNETKI RVPVGDSLQG 150
    SKWTCMKINE DEVTKEVTLQ VNIPPDAIIG RYKLTVEVAT ELKDGRQKER 200
    KVKPDIVVLF NPFKPADPVY MESSVEREEY VLNDTGRIYV GQWYRIGAKD 250
    WLFGQFEEGI LDIALKLLRE HTNAQKNATK SLKKRASPAY CSRLLSAMVN 300
    CNDDNGVLWG RWDGKYEEGV KPTTWSGSVA ILKQWNRTKM NPVKYGQCWV 350
    FSGLLTTVLR ALGIPARSIT NFNSAHDTEY NMTIDKFLTE DGESAEGTGD 400
    SIWNFHVWNE GFFRRPDLPK GYDGWQAVDA TPQEESSGVM QCGPAPIKAI 450
    KNGEIYIGSD TNFVFAEVNA DRVFWEVNDE GEVTKMVKND KRHVGRNIST 500
    KAVGSDERED VTLQYKFAEG SEEERVAFER AYAHGRKAPY HDKFVLEDEG 550
    NIKIDINPVG DVINGSDVSI SVKVTNAKGV DCDATITTVI HTMLNNEERK 600
    RLLKRSRGTR KIAAGKDDVE SFKFGFGDYG RHLSDENVIR VTTTVRVKET 650
    NKLYVDQYDI QIESPQCLEL ICADELKVRE YQPIRFKITN PLKVAMTSAV 700
    FSLQGSGISS GKSFEVPSPI EPGETYTSPE MEVRPYRSSR ATTILGDFDC 750
    NEIWNIKARK RVAVNF 766
    Length:766
    Mass (Da):87,194
    Last modified:November 1, 1998 - v2
    Checksum:i7F90D921D87FDD1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y10212 mRNA. Translation: CAA71263.1.
    RefSeqiNP_001027712.1. NM_001032540.1.
    UniGeneiCin.22973.

    Genome annotation databases

    GeneIDi445739.
    KEGGicin:445739.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y10212 mRNA. Translation: CAA71263.1 .
    RefSeqi NP_001027712.1. NM_001032540.1.
    UniGenei Cin.22973.

    3D structure databases

    ProteinModelPortali P91590.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7719.ENSCINP00000000870.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 445739.
    KEGGi cin:445739.

    Organism-specific databases

    CTDi 7052.

    Phylogenomic databases

    eggNOGi NOG80379.
    HOGENOMi HOG000231695.
    InParanoidi P91590.
    KOi K05625.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "A new transglutaminase-like from the ascidian Ciona intestinalis."
      Cariello L., Ristoratore F., Zanetti L.
      FEBS Lett. 408:171-176(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Cariello L.
      Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiP91590_CIOIN
    AccessioniPrimary (citable) accession number: P91590
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 1997
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 75 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)