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P91590

- P91590_CIOIN

UniProt

P91590 - P91590_CIOIN

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Protein
Submitted name:

Transglutiminase

Gene
N/A
Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei348 – 3481 By similarity
Active sitei406 – 4061 By similarity
Active sitei429 – 4291 By similarityUniRule annotation
Metal bindingi469 – 4691Calcium By similarityUniRule annotation
Metal bindingi471 – 4711Calcium By similarityUniRule annotation
Metal bindingi519 – 5191Calcium By similarityUniRule annotation
Metal bindingi524 – 5241Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TransglutiminaseImported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000000870.

Structurei

3D structure databases

ProteinModelPortaliP91590.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
HOGENOMiHOG000231695.
InParanoidiP91590.
KOiK05625.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

P91590-1 [UniParc]FASTAAdd to Basket

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MSRFRRRWFV IDAENAEEVN EFLDEHPRFL GEYIDRNPHL LDNYVIDNVD    50
EETIQKWLDK VSGPAPTEVL QILRVNYKKE TNCVDHHTDK YIHNSLVVRR 100
ATTFDLGLVF KNRNYRPAKD DIVLEFTIGS DPTIKNETKI RVPVGDSLQG 150
SKWTCMKINE DEVTKEVTLQ VNIPPDAIIG RYKLTVEVAT ELKDGRQKER 200
KVKPDIVVLF NPFKPADPVY MESSVEREEY VLNDTGRIYV GQWYRIGAKD 250
WLFGQFEEGI LDIALKLLRE HTNAQKNATK SLKKRASPAY CSRLLSAMVN 300
CNDDNGVLWG RWDGKYEEGV KPTTWSGSVA ILKQWNRTKM NPVKYGQCWV 350
FSGLLTTVLR ALGIPARSIT NFNSAHDTEY NMTIDKFLTE DGESAEGTGD 400
SIWNFHVWNE GFFRRPDLPK GYDGWQAVDA TPQEESSGVM QCGPAPIKAI 450
KNGEIYIGSD TNFVFAEVNA DRVFWEVNDE GEVTKMVKND KRHVGRNIST 500
KAVGSDERED VTLQYKFAEG SEEERVAFER AYAHGRKAPY HDKFVLEDEG 550
NIKIDINPVG DVINGSDVSI SVKVTNAKGV DCDATITTVI HTMLNNEERK 600
RLLKRSRGTR KIAAGKDDVE SFKFGFGDYG RHLSDENVIR VTTTVRVKET 650
NKLYVDQYDI QIESPQCLEL ICADELKVRE YQPIRFKITN PLKVAMTSAV 700
FSLQGSGISS GKSFEVPSPI EPGETYTSPE MEVRPYRSSR ATTILGDFDC 750
NEIWNIKARK RVAVNF 766
Length:766
Mass (Da):87,194
Last modified:November 1, 1998 - v2
Checksum:i7F90D921D87FDD1D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y10212 mRNA. Translation: CAA71263.1.
RefSeqiNP_001027712.1. NM_001032540.1.
UniGeneiCin.22973.

Genome annotation databases

GeneIDi445739.
KEGGicin:445739.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y10212 mRNA. Translation: CAA71263.1 .
RefSeqi NP_001027712.1. NM_001032540.1.
UniGenei Cin.22973.

3D structure databases

ProteinModelPortali P91590.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7719.ENSCINP00000000870.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 445739.
KEGGi cin:445739.

Organism-specific databases

CTDi 7052.

Phylogenomic databases

eggNOGi NOG80379.
HOGENOMi HOG000231695.
InParanoidi P91590.
KOi K05625.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A new transglutaminase-like from the ascidian Ciona intestinalis."
    Cariello L., Ristoratore F., Zanetti L.
    FEBS Lett. 408:171-176(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Cariello L.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP91590_CIOIN
AccessioniPrimary (citable) accession number: P91590
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: November 1, 1998
Last modified: July 9, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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