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Protein

Serpentine receptor class gamma-20

Gene

srg-20

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Serpentine receptor class gamma-20
Short name:
Protein srg-20
Gene namesi
Name:srg-20
ORF Names:ZC204.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiZC204.4a; CE36350; WBGene00005177; srg-20.
ZC204.4b; CE33252; WBGene00005177; srg-20.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei27 – 4721HelicalSequence analysisAdd
BLAST
Transmembranei69 – 8921HelicalSequence analysisAdd
BLAST
Transmembranei106 – 12823HelicalSequence analysisAdd
BLAST
Transmembranei157 – 17721HelicalSequence analysisAdd
BLAST
Transmembranei212 – 23221HelicalSequence analysisAdd
BLAST
Transmembranei254 – 27421HelicalSequence analysisAdd
BLAST
Transmembranei279 – 29921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Serpentine receptor class gamma-20PRO_0000104567Add
BLAST

Proteomic databases

PaxDbiP91535.

Expressioni

Gene expression databases

ExpressionAtlasiP91535. baseline.

Structurei

3D structure databases

ProteinModelPortaliP91535.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000064349.
HOGENOMiHOG000021110.
InParanoidiP91535.
PhylomeDBiP91535.

Family and domain databases

InterProiIPR000609. 7TM_GPCR_serpentine_rcpt_Srg.
[Graphical view]
PfamiPF02118. Srg. 1 hit.
[Graphical view]
PRINTSiPR00698. TMPROTEINSRG.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform b (identifier: P91535-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSTRLIIPAN FSYDDPLPFT CNQDSHVMLS ILEYLVQATY LSVSAVLNSM
60 70 80 90 100
IVYTIFRCKG KHSYRRNPFF VLYAAEAVMN VYSCVIEVLF GRLIIYMTPL
110 120 130 140 150
CPALSPFFFT PSILTKLYFL LNHYCLAFKT LSQIAISFNR MTCVIFPVHH
160 170 180 190 200
FKLWQNILAP VLVSLFVLPL GVTWNILVSR VYVNPNGAGF SVNYRDAVAW
210 220 230 240 250
ANISFLHLFH CIPCLFLMIV FFLASIFGLT MLENRLRSAE RSLIIFTMTL
260 270 280 290 300
GVETMLFAIA QIYFAFLAGY LPGIRPLMLL ISFNVFDVLY VYSPIALILM
310 320 330 340
NRQLRRDIFH LKGDDPGFGF TKFPVILVEM ISDSSPHLLI INLQLV
Note: No experimental confirmation available.
Length:346
Mass (Da):39,548
Last modified:September 19, 2006 - v4
Checksum:iFE75A7916E4F16D2
GO
Isoform a (identifier: P91535-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     319-346: GFTKFPVILVEMISDSSPHLLIINLQLV → LSASSHNQPAARVMAPVMH

Note: No experimental confirmation available.
Show »
Length:337
Mass (Da):38,428
Checksum:i6F4B74423854784E
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei319 – 34628GFTKF…NLQLV → LSASSHNQPAARVMAPVMH in isoform a. CuratedVSP_020532Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080436 Genomic DNA. Translation: CCD63684.1.
FO080436 Genomic DNA. Translation: CCD63685.1.
PIRiT25950.
RefSeqiNP_001022490.1. NM_001027319.2. [P91535-2]
NP_001022491.1. NM_001027320.1. [P91535-1]
UniGeneiCel.13829.

Genome annotation databases

EnsemblMetazoaiZC204.4b; ZC204.4b; WBGene00005177. [P91535-1]
GeneIDi191110.
KEGGicel:CELE_ZC204.4.
UCSCiZC204.4a. c. elegans. [P91535-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080436 Genomic DNA. Translation: CCD63684.1.
FO080436 Genomic DNA. Translation: CCD63685.1.
PIRiT25950.
RefSeqiNP_001022490.1. NM_001027319.2. [P91535-2]
NP_001022491.1. NM_001027320.1. [P91535-1]
UniGeneiCel.13829.

3D structure databases

ProteinModelPortaliP91535.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiP91535.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZC204.4b; ZC204.4b; WBGene00005177. [P91535-1]
GeneIDi191110.
KEGGicel:CELE_ZC204.4.
UCSCiZC204.4a. c. elegans. [P91535-1]

Organism-specific databases

CTDi191110.
WormBaseiZC204.4a; CE36350; WBGene00005177; srg-20.
ZC204.4b; CE33252; WBGene00005177; srg-20.

Phylogenomic databases

GeneTreeiENSGT00530000064349.
HOGENOMiHOG000021110.
InParanoidiP91535.
PhylomeDBiP91535.

Miscellaneous databases

NextBioi947986.
PROiP91535.

Gene expression databases

ExpressionAtlasiP91535. baseline.

Family and domain databases

InterProiIPR000609. 7TM_GPCR_serpentine_rcpt_Srg.
[Graphical view]
PfamiPF02118. Srg. 1 hit.
[Graphical view]
PRINTSiPR00698. TMPROTEINSRG.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
    Strain: Bristol N2.

Entry informationi

Entry nameiSRG20_CAEEL
AccessioniPrimary (citable) accession number: P91535
Secondary accession number(s): Q5DX28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: September 19, 2006
Last modified: November 11, 2015
This is version 84 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.