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Protein

Kinesin-like protein

Gene

klp-15

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent microtubule motor activity, minus-end-directed Source: WormBase

GO - Biological processi

  • microtubule-based movement Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

Motor proteinUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:klp-15Imported
ORF Names:CELE_M01E11.6Imported, M01E11.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiM01E11.6; CE12298; WBGene00002225; klp-15.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

EPDiP91400.
PaxDbiP91400.
PRIDEiP91400.

Expressioni

Gene expression databases

ExpressionAtlasiP91400. baseline and differential.

Interactioni

Protein-protein interaction databases

DIPiDIP-25275N.
IntActiP91400. 4 interactions.
MINTiMINT-1051346.
STRINGi6239.M01E11.6.

Structurei

3D structure databases

ProteinModelPortaliP91400.
SMRiP91400. Positions 198-565.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini248 – 566319Kinesin motorInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili179 – 20628Sequence analysisAdd
BLAST
Coiled coili214 – 24835Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.UniRule annotationSAAS annotation
Contains 1 kinesin motor domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0239. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00550000074610.
HOGENOMiHOG000016848.
InParanoidiP91400.
OrthoDBiEOG72G16X.
PhylomeDBiP91400.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 2 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P91400-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVARRRSGL FRSTIGATPK ITRGRAAAPS TKEANSTTIP RQSAPGGITI
60 70 80 90 100
GAAARRPPSR LPTPTTPATG RASLPERSAM AKPASCSRPI PTMQSTASRI
110 120 130 140 150
STLTAASTFR QLRTGRPPPP STQRSTATSS LKPSVTRARP VAQKPILPSK
160 170 180 190 200
MALLEEKIAQ LESAMAEATD FAEHQKSKIQ ILDGKLEGAD RKLISLQDQL
210 220 230 240 250
STLKEVNKAK VEECEDYRVH NNDLRDLLNE KEAELRKLHN DVVDLRGQIR
260 270 280 290 300
VAVRVRPLIK SEADASSSAI EYPAIDTIRI NEGSKPGIVV KFEKVFTPVF
310 320 330 340 350
SQKEVFANVE EFIRSSLHGY NVGLIAYGQT GSGKTHTMRG GNGEEEGIIP
360 370 380 390 400
RAAAFLFAES RKLESLGWKF DFSLSFLEVY NNVAYDLLSD RAVVQLRLND
410 420 430 440 450
QTVSMIGLSE HTISNVSDVA RLLRVADGGR KTAATKCNES SSRSHAVYMW
460 470 480 490 500
KITAHQPSTG ISTSCQLKLV DLAGSERAKE SGVSGDQFKE MTNINQSLSI
510 520 530 540 550
LQMCISQQRS QKGHVSYRDS KLTQVLMDCL GRGNSKTMVV VNLNPCNEQA
560 570 580
TESKRSIEFA SKMRSTNIGS AVQQRTLLGD VSQMSMN
Length:587
Mass (Da):64,073
Last modified:May 1, 1997 - v1
Checksum:iDFE606A065F0A872
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD71345.1.
PIRiT29324.
RefSeqiNP_491633.1. NM_059232.3.
UniGeneiCel.19521.

Genome annotation databases

EnsemblMetazoaiM01E11.6; M01E11.6; WBGene00002225.
GeneIDi172213.
KEGGicel:CELE_M01E11.6.
UCSCiM01E11.6. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD71345.1.
PIRiT29324.
RefSeqiNP_491633.1. NM_059232.3.
UniGeneiCel.19521.

3D structure databases

ProteinModelPortaliP91400.
SMRiP91400. Positions 198-565.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-25275N.
IntActiP91400. 4 interactions.
MINTiMINT-1051346.
STRINGi6239.M01E11.6.

Proteomic databases

EPDiP91400.
PaxDbiP91400.
PRIDEiP91400.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiM01E11.6; M01E11.6; WBGene00002225.
GeneIDi172213.
KEGGicel:CELE_M01E11.6.
UCSCiM01E11.6. c. elegans.

Organism-specific databases

CTDi172213.
WormBaseiM01E11.6; CE12298; WBGene00002225; klp-15.

Phylogenomic databases

eggNOGiKOG0239. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00550000074610.
HOGENOMiHOG000016848.
InParanoidiP91400.
OrthoDBiEOG72G16X.
PhylomeDBiP91400.

Miscellaneous databases

NextBioi874523.

Gene expression databases

ExpressionAtlasiP91400. baseline and differential.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 2 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiP91400_CAEEL
AccessioniPrimary (citable) accession number: P91400
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 11, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.