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Protein

Phospholipid-transporting ATPase

Gene

tat-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDAi3.6.3.1. 1045.

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipid-transporting ATPaseUniRule annotation (EC:3.6.3.1UniRule annotation)
Gene namesi
Name:tat-6Imported
ORF Names:CELE_F02C9.3Imported, F02C9.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF02C9.3; CE19775; WBGene00017174; tat-6.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei119 – 13719HelicalUniRule annotationAdd
BLAST
Transmembranei143 – 16220HelicalUniRule annotationAdd
BLAST
Transmembranei343 – 36220HelicalUniRule annotationAdd
BLAST
Transmembranei368 – 38821HelicalUniRule annotationAdd
BLAST
Transmembranei864 – 88623HelicalUniRule annotationAdd
BLAST
Transmembranei892 – 91221HelicalUniRule annotationAdd
BLAST
Transmembranei942 – 96221HelicalUniRule annotationAdd
BLAST
Transmembranei968 – 98922HelicalUniRule annotationAdd
BLAST
Transmembranei996 – 101621HelicalUniRule annotationAdd
BLAST
Transmembranei1028 – 104821HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiP91203.
PaxDbiP91203.
PRIDEiP91203.

Interactioni

Protein-protein interaction databases

STRINGi6239.F02C9.3.

Structurei

3D structure databases

ProteinModelPortaliP91203.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini90 – 14556PhoLip_ATPase_NInterPro annotationAdd
BLAST
Domaini152 – 395244E1-E2_ATPaseInterPro annotationAdd
BLAST
Domaini830 – 1057228PhoLip_ATPase_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0210. Eukaryota.
ENOG410XPYK. LUCA.
GeneTreeiENSGT00550000074723.
HOGENOMiHOG000201571.
InParanoidiP91203.
KOiK01530.
OMAiQHLANES.
OrthoDBiEOG75MVVF.
PhylomeDBiP91203.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 3 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P91203-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQNFTQSAY LNQCVSTEDF SVSFVKSEND DVATRIRDKT EISKSNRTQF
60 70 80 90 100
PGTSPFEKLT VWFQSLMSRQ RALHSRTVRI GYGPIDHDSP RTFPPNTVRN
110 120 130 140 150
QKYNIFSFVP VVLFQEFKFF LNLYFLIMAF SQLVPIFKIG ALVTYWFPLG
160 170 180 190 200
FILTITLIRE AIEDFARFLR DRELNSEKYE KLTRDGTRVE IKSADIKVGD
210 220 230 240 250
VIVMHKDRRV PADVVLLRTS DKSSSCFIRT DQLDGETDWK LKIPIPFTQH
260 270 280 290 300
LANESEIMEL NCEVYAEKPQ KDIYSFVGTV KITADDKIHE GSLDVENVLW
310 320 330 340 350
ANTVVSSGTA IGVVVYTGCE TRSVMNTTVP EYKVGLLDLE INNLTKLLFC
360 370 380 390 400
FVLLLASVMV LMKGPTSLWY LYLARFILLF SYIIPISLRT NVDMAKLFYS
410 420 430 440 450
WQIGHDHHIP ETVVRSSTIP EELGRISFLL SDKTGTLTKN EMHFKKIHLG
460 470 480 490 500
TVAFSGDALE EVEQHVKSAY DSALVKHPFS AKLKNAVESL ALCHNVTPVL
510 520 530 540 550
ENGELSYQAA SPDEVALVKW TETVGVKLAH RDLHTMTLDV QPSNGTTVPI
560 570 580 590 600
QFQILHVFPF TSERKRMGII VKEETSGEVT LYIKGADTVM SDMVQYNDWL
610 620 630 640 650
DEECTNMARE GLRTLVFAKK ILSRAELEAF DQAYHAAKMS ITNRTQNMAN
660 670 680 690 700
VVKNMLERDL QLICLTGVED RLQDQVTTSL ELLRNAGIKI WMLTGDKLET
710 720 730 740 750
AICIAKSSGL FSKSDHIHVF GSVQTRTDAY NELDNLRNKT NIALVMPGSS
760 770 780 790 800
LNICLQYYEE EVAELVCAST AVVCCRCSPE QKAQIVQLLR KYRAPLRVAA
810 820 830 840 850
IGDGGNDVSM IQAAHAGIGI DANEGKQASL AADFSITQFS HICRLLLVHG
860 870 880 890 900
RFSYKRSCTL AQFIMHRGLL ISIVQAIFSC VFYFVAVSLY QGVLMVAFTS
910 920 930 940 950
CYTLLPVFSL IADRDVTATN ALTYPELYKE LVKGRTLSYK TFFIWVFISI
960 970 980 990 1000
YQGAVIMYGA LLIFDTDILH IVSISFSALI ATELIMVALT VHTWHWLMLV
1010 1020 1030 1040 1050
AQALSLGLYV VSLITLDQFF DRKFVFSWVF ITKTTAITVV SSLPLYFIKT
1060
LRRKFSPPSF AKVK
Length:1,064
Mass (Da):120,128
Last modified:November 1, 1999 - v2
Checksum:i0B720AA29791A9F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD66878.1.
RefSeqiNP_503858.1. NM_071457.1.
UniGeneiCel.4261.

Genome annotation databases

EnsemblMetazoaiF02C9.3; F02C9.3; WBGene00017174.
GeneIDi178754.
KEGGicel:CELE_F02C9.3.
UCSCiF02C9.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD66878.1.
RefSeqiNP_503858.1. NM_071457.1.
UniGeneiCel.4261.

3D structure databases

ProteinModelPortaliP91203.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F02C9.3.

Proteomic databases

EPDiP91203.
PaxDbiP91203.
PRIDEiP91203.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF02C9.3; F02C9.3; WBGene00017174.
GeneIDi178754.
KEGGicel:CELE_F02C9.3.
UCSCiF02C9.3. c. elegans.

Organism-specific databases

CTDi178754.
WormBaseiF02C9.3; CE19775; WBGene00017174; tat-6.

Phylogenomic databases

eggNOGiKOG0210. Eukaryota.
ENOG410XPYK. LUCA.
GeneTreeiENSGT00550000074723.
HOGENOMiHOG000201571.
InParanoidiP91203.
KOiK01530.
OMAiQHLANES.
OrthoDBiEOG75MVVF.
PhylomeDBiP91203.

Enzyme and pathway databases

BRENDAi3.6.3.1. 1045.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 3 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiP91203_CAEEL
AccessioniPrimary (citable) accession number: P91203
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: November 1, 1999
Last modified: July 6, 2016
This is version 142 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.