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Protein

60S ribosomal protein L13

Gene

rpl-13

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L13
Gene namesi
Name:rpl-13
ORF Names:C32E8.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC32E8.2a; CE08526; WBGene00004425; rpl-13.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001929271 – 20760S ribosomal protein L13Add BLAST207

Proteomic databases

EPDiP91128.
PaxDbiP91128.
PeptideAtlasiP91128.
PRIDEiP91128.

PTM databases

iPTMnetiP91128.

Expressioni

Gene expression databases

BgeeiWBGene00004425.

Interactioni

Protein-protein interaction databases

BioGridi37423. 1 interactor.
DIPiDIP-25306N.
MINTiMINT-1074454.
STRINGi6239.C32E8.2a.1.

Structurei

3D structure databases

ProteinModelPortaliP91128.
SMRiP91128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L13e family.Curated

Phylogenomic databases

eggNOGiKOG3295. Eukaryota.
COG4352. LUCA.
GeneTreeiENSGT00390000007818.
HOGENOMiHOG000170452.
InParanoidiP91128.
KOiK02873.
OMAiVMPITNE.
OrthoDBiEOG091G0KGO.
PhylomeDBiP91128.

Family and domain databases

InterProiIPR001380. Ribosomal_L13e.
IPR018256. Ribosomal_L13e_CS.
[Graphical view]
PANTHERiPTHR11722. PTHR11722. 1 hit.
PfamiPF01294. Ribosomal_L13e. 1 hit.
[Graphical view]
PROSITEiPS01104. RIBOSOMAL_L13E. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform a (identifier: P91128-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPRGNQMLG NAHFRKHWHK RIKTWFDQPA RKLRRRQNRQ AKAVEIAPRP
60 70 80 90 100
VAGLLRSVVR CPQKRYNTKT RLGRGFSLQE LKAAGISQAQ ARTIGIAVDV
110 120 130 140 150
RRTNKTAEGL KANADRLKEY KAKLILFPKK ASAPKKGDSS AEELKVAAQL
160 170 180 190 200
RGDVLPLSHT ITFDEPRQVT DAERKVEIFR LLRKERADKK YRGKREKRAR

EAAEENK
Note: No experimental confirmation available.
Length:207
Mass (Da):23,753
Last modified:May 1, 1997 - v1
Checksum:i5D22A55C0AC01C36
GO
Isoform b (identifier: P91128-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     85-203: Missing.

Note: No experimental confirmation available.
Show »
Length:88
Mass (Da):10,386
Checksum:i6F065BE8970E6767
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_02072685 – 203Missing in isoform b. CuratedAdd BLAST119

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080749 Genomic DNA. Translation: CCD66399.1.
FO080749 Genomic DNA. Translation: CCD66400.1.
PIRiT25599.
RefSeqiNP_001021017.1. NM_001025846.3. [P91128-1]
UniGeneiCel.38570.

Genome annotation databases

EnsemblMetazoaiC32E8.2a; C32E8.2a; WBGene00004425. [P91128-1]
GeneIDi171949.
KEGGicel:CELE_C32E8.2.
UCSCiC32E8.2a.1. c. elegans. [P91128-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080749 Genomic DNA. Translation: CCD66399.1.
FO080749 Genomic DNA. Translation: CCD66400.1.
PIRiT25599.
RefSeqiNP_001021017.1. NM_001025846.3. [P91128-1]
UniGeneiCel.38570.

3D structure databases

ProteinModelPortaliP91128.
SMRiP91128.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi37423. 1 interactor.
DIPiDIP-25306N.
MINTiMINT-1074454.
STRINGi6239.C32E8.2a.1.

PTM databases

iPTMnetiP91128.

Proteomic databases

EPDiP91128.
PaxDbiP91128.
PeptideAtlasiP91128.
PRIDEiP91128.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC32E8.2a; C32E8.2a; WBGene00004425. [P91128-1]
GeneIDi171949.
KEGGicel:CELE_C32E8.2.
UCSCiC32E8.2a.1. c. elegans. [P91128-1]

Organism-specific databases

CTDi171949.
WormBaseiC32E8.2a; CE08526; WBGene00004425; rpl-13.

Phylogenomic databases

eggNOGiKOG3295. Eukaryota.
COG4352. LUCA.
GeneTreeiENSGT00390000007818.
HOGENOMiHOG000170452.
InParanoidiP91128.
KOiK02873.
OMAiVMPITNE.
OrthoDBiEOG091G0KGO.
PhylomeDBiP91128.

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP91128.

Gene expression databases

BgeeiWBGene00004425.

Family and domain databases

InterProiIPR001380. Ribosomal_L13e.
IPR018256. Ribosomal_L13e_CS.
[Graphical view]
PANTHERiPTHR11722. PTHR11722. 1 hit.
PfamiPF01294. Ribosomal_L13e. 1 hit.
[Graphical view]
PROSITEiPS01104. RIBOSOMAL_L13E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL13_CAEEL
AccessioniPrimary (citable) accession number: P91128
Secondary accession number(s): Q86GU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 1, 1997
Last modified: November 30, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.