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Protein
Submitted name:

DEgenerin Linked to Mechanosensation

Gene

delm-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Names & Taxonomyi

Protein namesi
Submitted name:
DEgenerin Linked to MechanosensationImported
Gene namesi
Name:delm-2Imported
ORF Names:C24G7.1Imported, CELE_C24G7.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC24G7.1; CE08351; WBGene00016063; delm-2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei89 – 114HelicalSequence analysisAdd BLAST26
Transmembranei503 – 529HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP91103.

Expressioni

Gene expression databases

BgeeiWBGene00016063.

Interactioni

Protein-protein interaction databases

STRINGi6239.C24G7.1.

Structurei

3D structure databases

ProteinModelPortaliP91103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91103.
OMAiFRTIEAM.
OrthoDBiEOG091G0FPY.
PhylomeDBiP91103.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

P91103-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPTISKPKT NQSTKSARKS SNESPYPSVT FRPNSSLSHL IIEVPVAQLK
60 70 80 90 100
KFKHAGETVS VERETQHFCE TTTMHGPKRI FQGKRWATLF WLIMVCTSIG
110 120 130 140 150
LLITQVCILA SNYLSKPVVS DVSFLINEEG IQFPQITICN FTPIRKTFVN
160 170 180 190 200
EMNKTGQISP NMINYIMHWF TEVPILIGSS NWQLLHEGNK DLQEYQKNNP
210 220 230 240 250
NFTVQGFFID AGFSCSDIFK LCSFQGETFD CCSISTPVLT PLGKCYTLDL
260 270 280 290 300
LSSTKPSMHK QTEPGIQAGL AITLDAHLEE QFDGSNGMDA LFTNSFVNGF
310 320 330 340 350
QYFVHPPNTI PHLSSDEFTV TPNSVAYTAI SSERFELLPT NKWGNCTEHY
360 370 380 390 400
PSGIKSDLPY LTGNCVSLCK AKFFMENCGC TPAVYNNERN LKECTPFETL
410 420 430 440 450
ACVNNHNGSN NATGKLEFKL PRCAQCAQQC NNLIYRAFNS QGNQFSARAF
460 470 480 490 500
EWFRTNNSNW TMAHIKTNFQ IIHIFYQDMS NTEYNQVQDA SISDLLSNIG
510 520 530 540 550
GNMGMFLGMS LITITEICLY FSKIIWLGIS KKRREYMYSK RVHEKTHKKE
560 570 580 590 600
IVETVEKMKV IESKRKLSSP IGFENQISWN SNDNVEFRIN LNNLEREFEA

VGSRSVLI
Length:608
Mass (Da):68,944
Last modified:May 1, 1997 - v1
Checksum:iF892183827BBCA4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63872.1.
PIRiT25572.
RefSeqiNP_491296.1. NM_058895.1.
UniGeneiCel.19207.

Genome annotation databases

EnsemblMetazoaiC24G7.1; C24G7.1; WBGene00016063.
GeneIDi182851.
KEGGicel:CELE_C24G7.1.
UCSCiC24G7.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63872.1.
PIRiT25572.
RefSeqiNP_491296.1. NM_058895.1.
UniGeneiCel.19207.

3D structure databases

ProteinModelPortaliP91103.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C24G7.1.

Proteomic databases

PaxDbiP91103.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC24G7.1; C24G7.1; WBGene00016063.
GeneIDi182851.
KEGGicel:CELE_C24G7.1.
UCSCiC24G7.1. c. elegans.

Organism-specific databases

CTDi182851.
WormBaseiC24G7.1; CE08351; WBGene00016063; delm-2.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91103.
OMAiFRTIEAM.
OrthoDBiEOG091G0FPY.
PhylomeDBiP91103.

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Gene expression databases

BgeeiWBGene00016063.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiP91103_CAEEL
AccessioniPrimary (citable) accession number: P91103
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: November 2, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.