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Protein
Submitted name:

Uncharacterized protein

Gene

acd-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • response to acidic pH Source: WormBase
  • sodium ion transport Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Protein family/group databases

TCDBi1.A.6.1.4. the epithelial na(+) channel (enac) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:acd-1Imported
ORF Names:C24G7.2Imported, CELE_C24G7.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC24G7.2; CE37320; WBGene00016064; acd-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei103 – 12523HelicalSequence analysisAdd
BLAST
Transmembranei519 – 54527HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • intrinsic component of membrane Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP91102.
PRIDEiP91102.

Expressioni

Gene expression databases

BgeeiWBGene00016064.

Interactioni

Protein-protein interaction databases

STRINGi6239.C24G7.2.

Structurei

3D structure databases

ProteinModelPortaliP91102.
SMRiP91102. Positions 146-532.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91102.
OMAiANFQMIN.
OrthoDBiEOG091G053J.
PhylomeDBiP91102.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

P91102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPTLSPNYR NEAFEHDDSY LVNFVAGSSS GESSTPPPSF VPKCNFRYNQ
60 70 80 90 100
SRSQMIIEVP VAQLKKLRKL EGTVSIKRET QHFCETTTMH GPKRIFQGKR
110 120 130 140 150
WATLFWLIMV SCSLGLLITQ VFILASEYLS KPTVSDVSFL INEDGMDFPL
160 170 180 190 200
ITICNLNPIR KTYVNEINKT GEVSPPMINY MMKWFTEIPT LIGGADRPTL
210 220 230 240 250
HEGNEELKLY MKNHLNFTVD SFFMNSGFSC PDIFKLCSFQ GEIFDCCTLS
260 270 280 290 300
TEVLTPLGKC FTLDLSSSTK ASMHKQTEPG IQAGLAITLD AHLEEQFDGS
310 320 330 340 350
NGMDALFTNS FVNGFRYFVH PPNTIPHLSS DEFTVSPNTV AFSAISSDRY
360 370 380 390 400
VLLPTHQWGN CTENFPDGIQ SNLSYSSGNC LSLCKAKFYM ENCGCTPALY
410 420 430 440 450
NIENNLKECT PYETTTCLDN ILAKPNKETG KIEFQTPNCK ACAQQCNSLV
460 470 480 490 500
YRAYNSYGSQ FSAGAFHYLK SINPEWTDGH MRANFQMINI FYRDMSYTEY
510 520 530 540 550
NQVQDASVTQ LLSDIGGNMG MFLGMSVITI TEICLFFSKM FWLGFSKKRR
560 570 580 590 600
DYMYSKRVNE KTHEREVCET VEKMKAIASQ GNLSSIAGTT SAKNSIPNDN
610 620 630
VEFRINLKDL ADQLDSDSGY SQNQPDSRNA SFQKY
Length:635
Mass (Da):71,604
Last modified:October 11, 2004 - v2
Checksum:iC8F04C713E2D7C24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63873.1.
PIRiT25571.
RefSeqiNP_491295.2. NM_058894.3.
UniGeneiCel.24978.

Genome annotation databases

EnsemblMetazoaiC24G7.2; C24G7.2; WBGene00016064.
GeneIDi182852.
KEGGicel:CELE_C24G7.2.
UCSCiC24G7.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63873.1.
PIRiT25571.
RefSeqiNP_491295.2. NM_058894.3.
UniGeneiCel.24978.

3D structure databases

ProteinModelPortaliP91102.
SMRiP91102. Positions 146-532.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C24G7.2.

Protein family/group databases

TCDBi1.A.6.1.4. the epithelial na(+) channel (enac) family.

Proteomic databases

PaxDbiP91102.
PRIDEiP91102.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC24G7.2; C24G7.2; WBGene00016064.
GeneIDi182852.
KEGGicel:CELE_C24G7.2.
UCSCiC24G7.2. c. elegans.

Organism-specific databases

CTDi182852.
WormBaseiC24G7.2; CE37320; WBGene00016064; acd-1.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91102.
OMAiANFQMIN.
OrthoDBiEOG091G053J.
PhylomeDBiP91102.

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Gene expression databases

BgeeiWBGene00016064.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiP91102_CAEEL
AccessioniPrimary (citable) accession number: P91102
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.