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Protein
Submitted name:

ACD-2

Gene

acd-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. sodium channel activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Submitted name:
ACD-2Imported
Gene namesi
Name:acd-2Imported
ORF Names:C24G7.4Imported, CELE_C24G7.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC24G7.4; CE08354; WBGene00016066; acd-2.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP91100.
PRIDEiP91100.

Interactioni

Protein-protein interaction databases

STRINGi6239.C24G7.4.

Structurei

3D structure databases

ProteinModelPortaliP91100.
SMRiP91100. Positions 81-500.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG262945.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91100.
OMAiSKIFWIM.
OrthoDBiEOG72VH5P.
PhylomeDBiP91100.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

P91100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQKSVYFNS LLSSLGISAI FEIKAAANKQ FANQLVIQVP VNSFKNGKKI
60 70 80 90 100
KGVGSAFRET KHFSSTTTMH GPKRIFYGKG VARAFWMLIV GLALAMLCFQ
110 120 130 140 150
IFILLQMYFS KPTLSQVSFI VNEGGMDFPA VTVCNFNPIK KSYVRELNVS
160 170 180 190 200
GDLTGETLEY LLQTNMDAMF LFSNLDRHNL KETHDEAETY FQNHTDFQII
210 220 230 240 250
KFLRTAGYDC GEIFDCCKYM KQKVTSLGKC WELDLRNLAP EWMRKQISPG
260 270 280 290 300
SEAGLQIVVD AQLEEELKGE NDDAKAIFSD IYENGFRYFI HPPGTNAQLT
310 320 330 340 350
SEGISVSPSR TVYSAIKTVT HNLLNRGNWG NCSENWPEGY NTFLSYSASA
360 370 380 390 400
CRALCIAQFF NDTCGCAPFT YNVDGRKKIC APYESITCMD NHMLKKVNGT
410 420 430 440 450
DYLELPDCEE CHMECQSTSY TSYNSYGDGF NRGSLEWLKK ISNKSETHIK
460 470 480 490 500
NNVAVINIFF LEMFYTSYSQ VQATSLTEIL SDIGGNMGMF LGMSVITITE
510 520 530 540 550
LSLFFSKIFW IMVSKRRRQY MYSKKTHEKE KEHQLDEAVK EFQERRSRRN
560 570 580 590 600
SRENISALGH YSNRITPVDD FQTKFGYKNA FSEGNMSNSS LDSVMELKFD
610 620 630 640 650
INELRRQLNQ PSTDGIARIR LPHQTSRQNS TENYYSSSPP IFTIEPMSRK
660
QSKTSLPSSL SPR
Length:663
Mass (Da):75,555
Last modified:April 30, 1997 - v1
Checksum:i70902E74493A0C27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63874.1.
PIRiT25569.
RefSeqiNP_491293.1. NM_058892.4.
UniGeneiCel.5275.

Genome annotation databases

EnsemblMetazoaiC24G7.4; C24G7.4; WBGene00016066.
GeneIDi171992.
KEGGicel:CELE_C24G7.4.
UCSCiC24G7.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63874.1.
PIRiT25569.
RefSeqiNP_491293.1. NM_058892.4.
UniGeneiCel.5275.

3D structure databases

ProteinModelPortaliP91100.
SMRiP91100. Positions 81-500.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C24G7.4.

Proteomic databases

PaxDbiP91100.
PRIDEiP91100.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC24G7.4; C24G7.4; WBGene00016066.
GeneIDi171992.
KEGGicel:CELE_C24G7.4.
UCSCiC24G7.4. c. elegans.

Organism-specific databases

CTDi171992.
WormBaseiC24G7.4; CE08354; WBGene00016066; acd-2.

Phylogenomic databases

eggNOGiNOG262945.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91100.
OMAiSKIFWIM.
OrthoDBiEOG72VH5P.
PhylomeDBiP91100.

Miscellaneous databases

NextBioi873571.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiP91100_CAEEL
AccessioniPrimary (citable) accession number: P91100
Entry historyi
Integrated into UniProtKB/TrEMBL: April 30, 1997
Last sequence update: April 30, 1997
Last modified: March 31, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.