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Protein
Submitted name:

Uncharacterized protein

Gene

acd-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:acd-2Imported
ORF Names:C24G7.4Imported, CELE_C24G7.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC24G7.4; CE51356; WBGene00016066; acd-2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei104 – 125HelicalSequence analysisAdd BLAST22
Transmembranei518 – 543HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP91100.

Expressioni

Gene expression databases

BgeeiWBGene00016066.

Interactioni

Protein-protein interaction databases

STRINGi6239.C24G7.4.

Structurei

3D structure databases

ProteinModelPortaliP91100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91100.
KOiK03440.
OrthoDBiEOG091G053J.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

P91100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLEDGPSTK PPDFENEKTQ ETSLSGEEFE NNSTLGTMRD AKSWAAANKQ
60 70 80 90 100
FANQLVIQVP VNSFKNGKKI KGVGSAFRET KHFSSTTTMH GPKRIFYGKG
110 120 130 140 150
VARAFWMLIV GLALAMLCFQ IFILLQMYFS KPTLSQVSFI VNEGGMDFPA
160 170 180 190 200
VTVCNFNPIK KSYVRELNVS GDLTGETLEY LLQTNMDAMF LFSNLDRHNL
210 220 230 240 250
KETHDEAETY FQNHTDFQII KFLRTAGYDC GEMFMTCYFG GRRFDCCKYM
260 270 280 290 300
KQKVTSLGKC WELDLRNLAP EWMRKQISPG SEAGLQIVVD AQLEEELKGE
310 320 330 340 350
NDDAKAIFSD IYENGFRYFI HPPGTNAQLT SEGISVSPSR TVYSAIKTVT
360 370 380 390 400
HNLLNRGNWG NCSENWPEGY NTFLSYSASA CRALCIAQFF NDTCGCAPFT
410 420 430 440 450
YNVDGRKKIC APYESITCMD NHMLKKVNGT DYLELPDCEE CHMECQSTSY
460 470 480 490 500
TSYNSYGDGF NRGSLEWLKK ISNKSETHIK NNVAVINIFF LEMFYTSYSQ
510 520 530 540 550
VQATSLTEIL SDIGGNMGMF LGMSVITITE LSLFFSKIFW IMVSKRRRQY
560 570 580 590 600
MYSKKTHEKE KEHQLDEAVK EFQERRSRRN SRENISALGH YSNRITPVDD
610 620 630 640 650
FQTKFGYKNA FSEGNMSNSS LDSVMELKFD INELRRQLNQ PSTDGIARIR
660 670 680 690
LPHQTSRQNS TENYYSSSPP IFTIEPMSRK QSKTSLPSSL SPR
Length:693
Mass (Da):79,041
Last modified:May 11, 2016 - v2
Checksum:i45B211BA75DA3349
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63874.2.
PIRiT25569.
RefSeqiNP_001309477.1. NM_001322671.1.

Genome annotation databases

EnsemblMetazoaiC24G7.4; C24G7.4; WBGene00016066.
GeneIDi171992.
KEGGicel:CELE_C24G7.4.
UCSCiC24G7.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD63874.2.
PIRiT25569.
RefSeqiNP_001309477.1. NM_001322671.1.

3D structure databases

ProteinModelPortaliP91100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C24G7.4.

Proteomic databases

PaxDbiP91100.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC24G7.4; C24G7.4; WBGene00016066.
GeneIDi171992.
KEGGicel:CELE_C24G7.4.
UCSCiC24G7.4. c. elegans.

Organism-specific databases

CTDi171992.
WormBaseiC24G7.4; CE51356; WBGene00016066; acd-2.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiP91100.
KOiK03440.
OrthoDBiEOG091G053J.

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Gene expression databases

BgeeiWBGene00016066.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiP91100_CAEEL
AccessioniPrimary (citable) accession number: P91100
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 11, 2016
Last modified: November 2, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.