skpo-2

Functionⁱ

GO - Molecular functionⁱ

heme binding Source: InterPro
peroxidase activity Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

response to oxidative stress Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Oxidoreductase, PeroxidaseImported

Molecular function

Oxidoreductase, PeroxidaseImported

Enzyme and pathway databases

Reactomeⁱ	R-CEL-209968. Thyroxine biosynthesis. R-CEL-6798695. Neutrophil degranulation.

Reactomeⁱ

R-CEL-209968. Thyroxine biosynthesis.
R-CEL-6798695. Neutrophil degranulation.

Protein family/group databases

PeroxiBaseⁱ	4142. CelPxd04.

PeroxiBaseⁱ

4142. CelPxd04.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ShK domain and PerOxidase domain containing proteinImported
Gene namesⁱ	Name:skpo-2Imported ORF Names:C16C8.2Imported, CELE_C16C8.2Imported
Organismⁱ	Caenorhabditis elegansImported
Taxonomic identifierⁱ	6239 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
Proteomesⁱ	UP000001940 Componentⁱ: Chromosome II

Organism-specific databases

WormBase More...WormBaseⁱ	C16C8.2; CE23553; WBGene00015841; skpo-2.

WormBaseⁱ

C16C8.2; CE23553; WBGene00015841; skpo-2.

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_5004161400	24 – 729	Sequence analysisAdd BLAST		706

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Disulfide bondⁱ	61 ↔ 95	PROSITE-ProRule annotation
Disulfide bondⁱ	101 ↔ 135	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

EPDⁱ	P91060.
PaxDbⁱ	P91060.
PeptideAtlas More...PeptideAtlasⁱ	P91060.

Expressionⁱ

Gene expression databases

Bgeeⁱ	WBGene00015841.

Bgeeⁱ

WBGene00015841.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	6239.C16C8.2.

STRINGⁱ

6239.C16C8.2.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P91060.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	61 – 95	ShKTInterPro annotationAdd BLAST		35
Domainⁱ	101 – 135	ShKTInterPro annotationAdd BLAST		35

Keywords - Domainⁱ

SignalSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG2408. Eukaryota. ENOG410XPZ3. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074325.
HOGENOMⁱ	HOG000016084.
InParanoidⁱ	P91060.
OMAⁱ	VSGLNCE.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02DF.
PhylomeDBⁱ	P91060.

Family and domain databases

Gene3Dⁱ	1.10.640.10. 1 hit.
InterProⁱ	View protein in InterPro IPR010255. Haem_peroxidase. IPR019791. Haem_peroxidase_animal. IPR037120. Haem_peroxidase_sf. IPR003582. ShKT_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03098. An_peroxidase. 1 hit. PF01549. ShK. 2 hits.
PRINTSⁱ	PR00457. ANPEROXIDASE.
SMARTⁱ	View protein in SMART SM00254. ShKT. 2 hits.
SUPFAMⁱ	SSF48113. SSF48113. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50292. PEROXIDASE_3. 1 hit. PS51670. SHKT. 2 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

P91060-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRKNSHLLVL FLLAIGTFQL ANADEENEVD ASGDSPPSVE GEVVEEAKST 
        60         70         80         90        100
AADDENVDKS CKDRHDLCKF WSSIGECTSN KNWMEDHCPV SCDFCNGITT 
       110        120        130        140        150
CIDRHRLCGF WATIRECETN AVWMLSNCPK ACKACKGRSV TLGGTGPGGT 
       160        170        180        190        200
FKEDDCTFIT TNEDTSIRKT LSIRDVRDSN ANFNCAPTQE TPNCNRNLCY 
       210        220        230        240        250
HLRYRSFDGT CNNLKKPMIG SAFTALMRLK NPMYDNGLNA PTSSFLRSRP 
       260        270        280        290        300
SARDASRLLL SSSTQIQHHS NALLMQWGQF IAHDLSKTTM LNNQECAACT 
       310        320        330        340        350
SNKGRCTSVF LSRSDPTFGR FMCLPVARST PVCGTGVSNF REQFNENTAF 
       360        370        380        390        400
IDGSMIYGSS DRDQFLFRQG AFLKTKLINN RVFPPVDKNN NVVAGDDRAN 
       410        420        430        440        450
IFVGLASLHV LYLRQHNRIA ATLQRVNPHW DQERVFHESR KIVGAMIQRI 
       460        470        480        490        500
TFTEYLPKVL GVAFEERIGA YPGYDPNIDP SVANEFTSCA FRFGHGMIQE 
       510        520        530        540        550
FYPFLNEKFQ HVGGIPFNDG MFKSTHILNN GIDPLIRGLM TLPAKMPQRL 
       560        570        580        590        600
TPAVTERIFG NSDLGSINIQ RGRDHGVPPY TVWRKFCGLP EVKDFEGLKQ 
       610        620        630        640        650
VISNQVVIDN LKVVYKHVDA IDMYVGSLLE DPVKDALVGP TLSCIIGEQF 
       660        670        680        690        700
KRTRNGDRLW YENSKVFSPE QLLQIKKITM SRVLCDAGEH FPMVPRKAFS 
       710        720 
VFKPTAHNLV KCDEIPDLDY NAWKEELAV

Length:729

Mass (Da):81,833

Last modified:October 1, 2001 - v2

Checksum:ⁱD925870565223E83

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284602 Genomic DNA. Translation: CCD64694.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_494540.1. NM_062139.6.
UniGeneⁱ	Cel.22979.

Genome annotation databases

EnsemblMetazoaⁱ	C16C8.2; C16C8.2; WBGene00015841.
GeneIDⁱ	173686.
KEGGⁱ	cel:CELE_C16C8.2.
UCSC genome browser More...UCSCⁱ	C16C8.2. c. elegans.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P91060	G0P632 G0NQK4 A8XRR7 A0A2G5V8L7 UPI0000120D75 K7HCM6 K7HCM7	Caenorhabditis brenneri (Nematode worm) Caenorhabditis briggsae Caenorhabditis nigoni Caenorhabditis japonica	729	UniRef90_P91060	Cluster: ShK domain and PerOxidase domain containing protein	8

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P91060	G0P632 G0NQK4 A0A2G5V8L7 A8XRR7 UPI0000120D75 K7HCM6 K7HCM7 A0A1I8CTS3 A0A1I7SX44 A0A260ZMD0 +20	Caenorhabditis brenneri (Nematode worm) Caenorhabditis nigoni Caenorhabditis briggsae Caenorhabditis japonica Rhabditophanes sp. KR3021 Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides xylophilus) Caenorhabditis remanei (Caenorhabditis vulgaris) Caenorhabditis latens Parastrongyloides trichosuri (Possum-specific nematode worm) Angiostrongylus costaricensis (Nematode worm) And more	729	UniRef50_P91060	Cluster: ShK domain and PerOxidase domain containing protein	31

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284602 Genomic DNA. Translation: CCD64694.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_494540.1. NM_062139.6.
UniGeneⁱ	Cel.22979.

3D structure databases

ProteinModelPortalⁱ	P91060.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	6239.C16C8.2.

STRINGⁱ

6239.C16C8.2.

Protein family/group databases

PeroxiBaseⁱ	4142. CelPxd04.

PeroxiBaseⁱ

4142. CelPxd04.

Proteomic databases

EPDⁱ	P91060.
PaxDbⁱ	P91060.
PeptideAtlas More...PeptideAtlasⁱ	P91060.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	C16C8.2; C16C8.2; WBGene00015841.
GeneIDⁱ	173686.
KEGGⁱ	cel:CELE_C16C8.2.
UCSC genome browser More...UCSCⁱ	C16C8.2. c. elegans.

Organism-specific databases

CTDⁱ	173686.
WormBase More...WormBaseⁱ	C16C8.2; CE23553; WBGene00015841; skpo-2.

Phylogenomic databases

eggNOGⁱ	KOG2408. Eukaryota. ENOG410XPZ3. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074325.
HOGENOMⁱ	HOG000016084.
InParanoidⁱ	P91060.
OMAⁱ	VSGLNCE.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02DF.
PhylomeDBⁱ	P91060.

Enzyme and pathway databases

Reactomeⁱ	R-CEL-209968. Thyroxine biosynthesis. R-CEL-6798695. Neutrophil degranulation.

Reactomeⁱ

R-CEL-209968. Thyroxine biosynthesis.
R-CEL-6798695. Neutrophil degranulation.

Gene expression databases

Bgeeⁱ	WBGene00015841.

Bgeeⁱ

WBGene00015841.

Family and domain databases

Gene3Dⁱ	1.10.640.10. 1 hit.
InterProⁱ	View protein in InterPro IPR010255. Haem_peroxidase. IPR019791. Haem_peroxidase_animal. IPR037120. Haem_peroxidase_sf. IPR003582. ShKT_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03098. An_peroxidase. 1 hit. PF01549. ShK. 2 hits.
PRINTSⁱ	PR00457. ANPEROXIDASE.
SMARTⁱ	View protein in SMART SM00254. ShKT. 2 hits.
SUPFAMⁱ	SSF48113. SSF48113. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50292. PEROXIDASE_3. 1 hit. PS51670. SHKT. 2 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	P91060_CAEEL
Accessionⁱ	P91060Primary (citable) accession number: P91060
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 1, 1997
	Last sequence update:	October 1, 2001
	Last modified:	February 28, 2018
	This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P91060 (P91060_CAEEL)

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ShK domain and PerOxidase domain containing protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ