Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Proteasome subunit beta

Gene

pbs-7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69017. CDK-mediated phosphorylation and removal of Cdc6.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-8948751. Regulation of PTEN stability and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Protein family/group databases

MEROPSiT01.A08.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit betaUniRule annotation (EC:3.4.25.1UniRule annotation)
Gene namesi
Name:pbs-7Imported
ORF Names:CELE_F39H11.5Imported, F39H11.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF39H11.5; CE20761; WBGene00003953; pbs-7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation, ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiP90868.
PaxDbiP90868.
PeptideAtlasiP90868.

Expressioni

Gene expression databases

BgeeiWBGene00003953.

Interactioni

Protein-protein interaction databases

DIPiDIP-26967N.
IntActiP90868. 9 interactors.
MINTiMINT-211920.
STRINGi6239.F39H11.5.

Structurei

3D structure databases

ProteinModelPortaliP90868.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0185. Eukaryota.
ENOG410YAMA. LUCA.
GeneTreeiENSGT00390000000698.
HOGENOMiHOG000181719.
InParanoidiP90868.
KOiK02736.
OMAiKECMKVL.
OrthoDBiEOG091G0JV7.
PhylomeDBiP90868.

Family and domain databases

CDDicd03760. proteasome_beta_type_4. 1 hit.
Gene3Di3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR029055. Ntn_hydrolases_N.
IPR016295. Proteasome_endopept_cplx_B.
IPR001353. Proteasome_sua/b.
PANTHERiPTHR11599:SF72. PTHR11599:SF72. 1 hit.
PfamiView protein in Pfam
PF00227. Proteasome. 1 hit.
PIRSFiPIRSF001213. Psome_endopept_beta. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.

Sequencei

Sequence statusi: Complete.

P90868-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAHDEVQRT LNPTCTGTSV IALQYKTGVV VLTDRVVSYG KMARYKNVSR
60 70 80 90 100
QYKVNDNVLI AFGGDHADFH WLQNVIERQV LLWKRFDQDI GPKALHGYLT
110 120 130 140 150
SLLYAKRCKM NPVWNTLVVA GVEEEEKNNK ETSTPFIGVI TQKGCAYQVK
160 170 180 190 200
HIATGLGAFL LNQAVEDEWR KKGEDLSREE AEAVLRKSLE LTLYHDCVAD
210 220 230
NEFEIGRVDA TEGVVLGKEE KIIGDWSIAE TNCQYE
Length:236
Mass (Da):26,682
Last modified:May 1, 1999 - v2
Checksum:iCFA2C116C799DABB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB03081.1.
PIRiT22003.
RefSeqiNP_492354.1. NM_059953.4.
UniGeneiCel.18394.

Genome annotation databases

EnsemblMetazoaiF39H11.5; F39H11.5; WBGene00003953.
GeneIDi172674.
KEGGicel:CELE_F39H11.5.
UCSCiF39H11.5.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiP90868_CAEEL
AccessioniPrimary (citable) accession number: P90868
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1999
Last modified: September 27, 2017
This is version 134 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported