P90795 (GPDM_CAEEL) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 95.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable glycerol-3-phosphate dehydrogenase, mitochondrial Short name=GPD-M Short name=GPDH-M EC=1.1.5.3 | ||
| Gene names |
| ||
| Organism | Caenorhabditis elegans | ||
| Taxonomic identifier | 6239 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Protein attributes
| Sequence length | 722 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Catalytic activity | sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. |
| Cofactor | FAD By similarity. |
| Enzyme regulation | Calcium-binding enhance the activity of the enzyme. |
| Pathway | |
| Subcellular location | Mitochondrion By similarity. |
| Sequence similarities | Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. Contains 2 EF-hand domains. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Mitochondrion |
| Domain | Repeat Transit peptide |
| Ligand | Calcium FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | glycerol-3-phosphate dehydrogenase complex Inferred from electronic annotation. Source: InterPro mitochondrionInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | calcium ion binding Inferred from electronic annotation. Source: InterPro sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transit peptide | 1 – 43 | 43 | Mitochondrion | ||||||
| Chain | 44 – 722 | 679 | Probable glycerol-3-phosphate dehydrogenase, mitochondrial | PRO_0000010432 | |||||
Regions | |||||||||
| Domain | 624 – 659 | 36 | EF-hand 1 | ||||||
| Domain | 660 – 695 | 36 | EF-hand 2 | ||||||
| Nucleotide binding | 76 – 104 | 29 | FAD Potential | ||||||
| Calcium binding | 673 – 684 | 12 | Potential | ||||||
Sequences
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References
| [1] | "Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | Z73906, Z72516 Genomic DNA. Translation: CAA98123.1. Z72516, Z73906 Genomic DNA. Translation: CAA96690.1. |
| PIR | T20362. |
| RefSeq | NP_492115.1. NM_059714.3. |
| UniGene | Cel.7665. |
3D structure databases | |
| ProteinModelPortal | P90795. |
| SMR | P90795. Positions 58-609, 622-692. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P90795. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblMetazoa | T25G3.4.1; T25G3.4.1; T25G3.4. T25G3.4.2; T25G3.4.2; T25G3.4. |
| GeneID | 172509. |
| KEGG | cel:T25G3.4. |
| NMPDR | fig|6239.3.peg.1942. |
| UCSC | T25G3.4. c. elegans. |
Organism-specific databases | |
| CTD | 172509. |
| WormBase | T25G3.4; CE14180; WBGene00012031. |
Phylogenomic databases | |
| eggNOG | meNOG05312. |
| GeneTree | EMGT00050000004719. |
| HOGENOM | HBG720894. |
| InParanoid | P90795. |
| OMA | DSIRKMD. |
| PhylomeDB | P90795. |
Gene expression databases | |
| ArrayExpress | P90795. |
Family and domain databases | |
| InterPro | IPR011992. EF-hand-like_dom. IPR018247. EF_Hand_1_Ca_BS. IPR018249. EF_HAND_2. IPR002048. EF_hand_Ca-bd. IPR006076. FAD-dep_OxRdtase. IPR000447. G3P_DH_FAD-dep. [Graphical view] |
| Gene3D | G3DSA:1.10.238.10. EF-Hand_type. 1 hit. |
| KO | K00111. |
| Pfam | PF01266. DAO. 1 hit. [Graphical view] |
| PRINTS | PR01001. FADG3PDH. |
| SMART | SM00054. EFh. 2 hits. [Graphical view] |
| PROSITE | PS00018. EF_HAND_1. 1 hit. PS50222. EF_HAND_2. 2 hits. PS00977. FAD_G3PDH_1. 1 hit. PS00978. FAD_G3PDH_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 875825. |
Entry information
| Entry name | GPDM_CAEEL | ||||||||
| Accession | Primary (citable) accession number: P90795 Secondary accession number(s): Q22793 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Caenorhabditis annotation project | ||||||||
Relevant documents
| Caenorhabditis elegans Caenorhabditis elegans: entries, gene names and cross-references to WormPep |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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