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Protein

alpha-1,2-Mannosidase

Gene

mans-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseCurated, Hydrolase

Enzyme and pathway databases

ReactomeiR-CEL-964827. Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseCurated (EC:3.2.1.-Curated)
Gene namesi
Name:mans-10 Publication
ORF Names:CELE_D2030.10 Publication, D2030.10 Publication
OrganismiCaenorhabditis elegans0 Publication
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiD2030.1; CE09078; WBGene00008411; mans-1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalCuratedAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiP90787.
PaxDbiP90787.
PeptideAtlasiP90787.

Expressioni

Gene expression databases

BgeeiWBGene00008411.

Interactioni

Protein-protein interaction databases

STRINGi6239.D2030.1.1.

Structurei

3D structure databases

ProteinModelPortaliP90787.
SMRiP90787.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helixCurated

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181987.
InParanoidiP90787.
KOiK01230.
OMAiDHKPGPG.
OrthoDBiEOG091G04C8.
PhylomeDBiP90787.

Family and domain databases

InterProiView protein in InterPro
IPR001382. Glyco_hydro_47.
IPR036026. Seven-hairpin_glycosidases.
PfamiView protein in Pfam
PF01532. Glyco_hydro_47. 1 hit.
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

P90787-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLRSHEQLV VCVGVMFLLT VCITAFFFLP SGGADLYFRE ENSVHVRDVL
60 70 80 90 100
IREEIRRKEQ DELRRKAEEA NPIPIPKPEI GASDDAEGRR IFVKQMIKFA
110 120 130 140 150
WDGYRKYAWG ENELRPNSRS GHSSSIFGYG KTGATIIDAI DTLYLVGLKE
160 170 180 190 200
EYKEARDWIA DFDFKTSAKG DLSVFETNIR FTGGLLSAFA LTGDKMFLKK
210 220 230 240 250
AEDVATILLP AFETPSGIPN SLIDAQTGRS KTYSWASGKA ILSEYGSIQL
260 270 280 290 300
EFDYLSNLTG NPVFAQKADK IRDVLTAMEK PEGLYPIYIT MDNPPRWGQH
310 320 330 340 350
LFSMGAMADS WYEYLLKQWI ATGKKDDRTK REYEEAIFAM EKRMLFKSEQ
360 370 380 390 400
SNLWYFAKMN GNRMEHSFEH LACFSGGMVV LHAMNEKNKT ISDHYMTLGK
410 420 430 440 450
EIGHTCHESY ARSTTGIGPE SFQFTSSVEA KTERRQDSYY ILRPEVVETW
460 470 480 490 500
FYLWRATKDE KYRQWAWDHV QNLEEYCKGT AGYSGIRNVY ESSPEQDDVQ
510 520 530 540
QSFLFAELFK YLYLIFSEDN ILPLDQWVFN TEAHPFRIRH
Length:540
Mass (Da):62,290
Last modified:May 1, 1997 - v1
Checksum:iA4C5A0E9D6FB8F3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAA98114.1.
PIRiT20352.
RefSeqiNP_492116.1. NM_059715.5.
UniGeneiCel.38845.

Genome annotation databases

EnsemblMetazoaiD2030.1.1; D2030.1.1; WBGene00008411.
D2030.1.2; D2030.1.2; WBGene00008411.
GeneIDi172510.
KEGGicel:CELE_D2030.1.
UCSCiD2030.1.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiP90787_CAEEL
AccessioniPrimary (citable) accession number: P90787
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: October 25, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationIEA:, Reference proteome0 Publication