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Protein

alpha-1,2-Mannosidase

Gene

mans-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-CEL-964827. Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:mans-1Imported
ORF Names:CELE_D2030.1Imported, D2030.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiD2030.1; CE09078; WBGene00008411; mans-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiP90787.
PaxDbiP90787.

Interactioni

Protein-protein interaction databases

STRINGi6239.D2030.1.1.

Structurei

3D structure databases

ProteinModelPortaliP90787.
SMRiP90787. Positions 89-538.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181987.
InParanoidiP90787.
KOiK01230.
OMAiYFREENS.
OrthoDBiEOG7X0VH1.
PhylomeDBiP90787.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

P90787-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLRSHEQLV VCVGVMFLLT VCITAFFFLP SGGADLYFRE ENSVHVRDVL
60 70 80 90 100
IREEIRRKEQ DELRRKAEEA NPIPIPKPEI GASDDAEGRR IFVKQMIKFA
110 120 130 140 150
WDGYRKYAWG ENELRPNSRS GHSSSIFGYG KTGATIIDAI DTLYLVGLKE
160 170 180 190 200
EYKEARDWIA DFDFKTSAKG DLSVFETNIR FTGGLLSAFA LTGDKMFLKK
210 220 230 240 250
AEDVATILLP AFETPSGIPN SLIDAQTGRS KTYSWASGKA ILSEYGSIQL
260 270 280 290 300
EFDYLSNLTG NPVFAQKADK IRDVLTAMEK PEGLYPIYIT MDNPPRWGQH
310 320 330 340 350
LFSMGAMADS WYEYLLKQWI ATGKKDDRTK REYEEAIFAM EKRMLFKSEQ
360 370 380 390 400
SNLWYFAKMN GNRMEHSFEH LACFSGGMVV LHAMNEKNKT ISDHYMTLGK
410 420 430 440 450
EIGHTCHESY ARSTTGIGPE SFQFTSSVEA KTERRQDSYY ILRPEVVETW
460 470 480 490 500
FYLWRATKDE KYRQWAWDHV QNLEEYCKGT AGYSGIRNVY ESSPEQDDVQ
510 520 530 540
QSFLFAELFK YLYLIFSEDN ILPLDQWVFN TEAHPFRIRH
Length:540
Mass (Da):62,290
Last modified:May 1, 1997 - v1
Checksum:iA4C5A0E9D6FB8F3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAA98114.1.
PIRiT20352.
RefSeqiNP_492116.1. NM_059715.5.
UniGeneiCel.38845.

Genome annotation databases

EnsemblMetazoaiD2030.1.1; D2030.1.1; WBGene00008411.
D2030.1.2; D2030.1.2; WBGene00008411.
GeneIDi172510.
KEGGicel:CELE_D2030.1.
UCSCiD2030.1.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAA98114.1.
PIRiT20352.
RefSeqiNP_492116.1. NM_059715.5.
UniGeneiCel.38845.

3D structure databases

ProteinModelPortaliP90787.
SMRiP90787. Positions 89-538.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.D2030.1.1.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Proteomic databases

EPDiP90787.
PaxDbiP90787.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiD2030.1.1; D2030.1.1; WBGene00008411.
D2030.1.2; D2030.1.2; WBGene00008411.
GeneIDi172510.
KEGGicel:CELE_D2030.1.
UCSCiD2030.1.1. c. elegans.

Organism-specific databases

CTDi172510.
WormBaseiD2030.1; CE09078; WBGene00008411; mans-1.

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181987.
InParanoidiP90787.
KOiK01230.
OMAiYFREENS.
OrthoDBiEOG7X0VH1.
PhylomeDBiP90787.

Enzyme and pathway databases

ReactomeiR-CEL-964827. Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiP90787_CAEEL
AccessioniPrimary (citable) accession number: P90787
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: July 6, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.