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Protein
Submitted name:

Cathepsin B cysteine proteinase 6

Gene

pXY14

Organism
Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC01.A51.

Names & Taxonomyi

Protein namesi
Submitted name:
Cathepsin B cysteine proteinase 6Imported
Submitted name:
Cathepsin B-like cysteine proteinaseImported
Gene namesi
Name:pXY14Imported
OrganismiAscaris suum (Pig roundworm) (Ascaris lumbricoides)Imported
Taxonomic identifieri6253 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaAscarididaAscaridoideaAscarididaeAscaris

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717UniRule annotationAdd
BLAST
Chaini18 – 398381UniRule annotationPRO_5006528444Add
BLAST

Structurei

3D structure databases

SMRiP90685. Positions 121-374.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini121 – 372252Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P90685-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYTFLVALL AIANSSADRR HLIDDSSSSD ESYGSRYYGD GRSVLDEFRD
60 70 80 90 100
RKISHEAEKL TGYALANYVN RKQNLWKAKF NNKFRNYSDR VKYGLMGVNN
110 120 130 140 150
VRLSVKAKKN LSPTRFYDIY IPEAFDAREK WDQCASLKNI RDQSSCGSCW
160 170 180 190 200
AFGAVEAMSD RICIASNGKI QVSLSADDLL SCCKSCGFGC DGGDPMAAWK
210 220 230 240 250
YWVKEGIVTG SNFTMKQGCK PYPFPPCEHH SNKTHYQPCK HDLYPTPKCE
260 270 280 290 300
KKCLDIYTEK TYAEDKFFGE TAYGVEDDVT SIQKEILTHG PVEVAFEVYE
310 320 330 340 350
DFLMYDGGIY VHTGGKIGGG HAVKMLGWGV EQGVPYWLVA NSWNTDWGED
360 370 380 390
GFFRIIRGID ECGIESSVVG GLPKLNRTYK KYHRRYRLDN DEDDDIIF
Length:398
Mass (Da):45,210
Last modified:May 1, 1997 - v1
Checksum:i5B3A6C7B03E59BFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51892 mRNA. Translation: AAB40605.1.
JI173046 mRNA. Translation: ADY46062.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51892 mRNA. Translation: AAB40605.1.
JI173046 mRNA. Translation: ADY46062.1.

3D structure databases

SMRiP90685. Positions 121-374.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiC01.A51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Xia Y., Moore J., Kennedy M.W.
    Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles."
    Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J., Davis R.E.
    Genome Res. 21:1462-1477(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP90685_ASCSU
AccessioniPrimary (citable) accession number: P90685
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 11, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.