Reviewed, UniProtKB/Swiss-Prot P90682 (CATA_ASCSU)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:

CAT

Organism

Ascaris suum (Pig roundworm) (Ascaris lumbricoides)

Taxonomic identifier

6253 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Ascaridida › Ascaridoidea › Ascarididae › Ascaris

Protein attributes

Sequence length	541 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group By similarity.
Subcellular location	PeroxisomeBy similarity.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 541	541	Catalase		PRO_0000084908
Sites
	Active site	74	1	By similarity
	Active site	147	1	By similarity
	Metal binding	357	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P90682-1 [UniParc]. Last modified January 1, 1998. Version 2. Checksum: 70890E1AECA170B0	FASTA	541	61,962
	10 20 30 40 50 60 MPQTKGKPHE EQLEQYKNSQ TKPFVLTTSN GAPIFNKKAS LTVGPRGPLL LQDVVFLDEM 70 80 90 100 110 120 AHFDRERIPE RVVHAKGGGA HGFFEVTDDI TKYCKADVFS TIGKRTPIFI RFSTVGGELG 130 140 150 160 170 180 SADTQRDPRG FAIKFYTEEG NWDLVGNNTP IFFIRDPIFF PNFIHTQKRN PVTHLKDPNM 190 200 210 220 230 240 MWDFFSLRPE TTHQVMILFG DRGIPDGFRH MDGFGSHTFK LVNKDGNAVY CKFHIKTAQG 250 260 270 280 290 300 IRNLPPDVAI KLAGEDPDYS IRDLYDSIEN GNYPVWRLMI QVMTFEEAAN YRFNPFDITK 310 320 330 340 350 360 VWSHKEFPLI LVGKIVLNKN PTNYFAEVEQ IAFAPSHVVP GIEFSPDKML QGRLFAYPDT 370 380 390 400 410 420 QFHRLGPNYV QLPINCPYRS RAHNTQRDGC FALDYNQGGM PTYHPNSFNG AIERTDVKES 430 440 450 460 470 480 AWSVSGDVDR FNGDDEDNFS QPRDLWLKVM DETERARLVD NIADSLKYCK AFIQERAINN 490 500 510 520 530 540 FTQVHQDFGN ALRNALQKAN EAMQKKREEE AEFNAKESVM MPCAIDDRMK NISNLAKYCK Y

References

[1]	Eckelt V.H.O. Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y10611 mRNA. Translation: CAA71618.1.
3D structure databases
HSSP	HSSP built from PDB template 1F4J based on UniProtKB P04040.
ModBase	Search...
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 2 hits. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_ASCSU

Accession

Primary (citable) accession number: P90682

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 1, 1998
Last modified:	November 25, 2008
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)