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Protein

Tubulin gamma-2 chain

Gene
N/A
Organism
Euplotes octocarinatus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi142 – 148GTPSequence analysis7

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin gamma-2 chain
Alternative name(s):
Gamma-2-tubulin
OrganismiEuplotes octocarinatus
Taxonomic identifieri5937 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataSpirotricheaHypotrichiaEuplotidaEuplotidaeEuplotes

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000484631 – 461Tubulin gamma-2 chainAdd BLAST461

Proteomic databases

PRIDEiP90548

Structurei

3D structure databases

ProteinModelPortaliP90548
SMRiP90548
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tubulin family.Curated

Family and domain databases

CDDicd02188 gamma_tubulin, 1 hit
Gene3Di1.10.287.600, 1 hit
3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
InterProiView protein in InterPro
IPR002454 Gamma_tubulin
IPR008280 Tub_FtsZ_C
IPR000217 Tubulin
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR023123 Tubulin_C
IPR017975 Tubulin_CS
IPR003008 Tubulin_FtsZ_GTPase
PANTHERiPTHR11588 PTHR11588, 1 hit
PfamiView protein in Pfam
PF00091 Tubulin, 1 hit
PF03953 Tubulin_C, 1 hit
PRINTSiPR01164 GAMMATUBULIN
PR01161 TUBULIN
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
PROSITEiView protein in PROSITE
PS00227 TUBULIN, 1 hit

Sequencei

Sequence statusi: Complete.

P90548-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPREIITCQV GQCGNQIGME FWKQLCMEHG INPEGILEDF AVNGEDRKDV
60 70 80 90 100
FFYQADDEHY VPRAVLIDLE PRVINGIQKS AYSSLYNPEN IYIAKHGGGA
110 120 130 140 150
GNNWGRGYTD AEKVQDEILE MIDREADGSD SLEGFVLTHS IAGGTGSGFG
160 170 180 190 200
SYLLERLNDH YPKKLIQTYS VFPIENDVVV QPYNCLLSIK RLTLNADCVV
210 220 230 240 250
VLDNNALTSI AVDRLKILQP TFSQINSIVS TVMAASTTTL RYPGYMNNDM
260 270 280 290 300
VGLIASLVPT PRCHFLMTGY TPLSLDQKFT SVRKTTVLDV MRRLLQTKNI
310 320 330 340 350
MVTGAVKKGA YMSILNVIQG DVDPTQVHKS LQRIRERKLA NFIPWGPASI
360 370 380 390 400
QVALSKKSPY IDSGHKVSGL MLANHTGIRS IFKVLYDQYR TFRKRDAYMN
410 420 430 440 450
IFKQTKIFED NLDEFDSSDE VVKSLIDEYA AAEKMDYINW GSDDDDMQFD
460
PREPPKFSNI Q
Length:461
Mass (Da):51,952
Last modified:May 1, 1997 - v1
Checksum:iDBED624C4B824A46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09553 Genomic DNA Translation: CAA70744.1
Y17254 Genomic DNA Translation: CAA76714.1

Similar proteinsi

Entry informationi

Entry nameiTBG2_EUPOC
AccessioniPrimary (citable) accession number: P90548
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

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