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Protein

Nucleoprotein

Gene

N

Organism
Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiCrimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV)
Taxonomic identifieri652961 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesBunyaviridaeNairovirus
Virus hostiBos taurus (Bovine) [TaxID: 9913]
Capra hircus (Goat) [TaxID: 9925]
Homo sapiens (Human) [TaxID: 9606]
Hyalomma [TaxID: 34625]
Ovis aries (Sheep) [TaxID: 9940]
Rhipicephalus microplus (Cattle tick) (Boophilus microplus) [TaxID: 6941]
Proteomesi
  • UP000008767 Componenti: Genome

Subcellular locationi

  • Virion By similarity

  • Note: Internal protein of virus particle.

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004065681 – 482NucleoproteinAdd BLAST482

Structurei

Secondary structure

1482
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi10 – 21Combined sources12
Beta strandi29 – 33Combined sources5
Helixi44 – 50Combined sources7
Helixi56 – 71Combined sources16
Turni72 – 74Combined sources3
Helixi77 – 83Combined sources7
Helixi86 – 97Combined sources12
Turni100 – 103Combined sources4
Helixi104 – 108Combined sources5
Helixi110 – 113Combined sources4
Helixi120 – 137Combined sources18
Helixi143 – 145Combined sources3
Helixi160 – 162Combined sources3
Helixi163 – 181Combined sources19
Helixi196 – 204Combined sources9
Turni205 – 207Combined sources3
Helixi209 – 213Combined sources5
Beta strandi227 – 229Combined sources3
Helixi230 – 242Combined sources13
Helixi245 – 263Combined sources19
Turni264 – 267Combined sources4
Helixi270 – 300Combined sources31
Helixi306 – 316Combined sources11
Turni321 – 323Combined sources3
Helixi324 – 336Combined sources13
Helixi341 – 350Combined sources10
Helixi355 – 360Combined sources6
Turni365 – 367Combined sources3
Helixi372 – 374Combined sources3
Turni382 – 384Combined sources3
Helixi385 – 392Combined sources8
Helixi400 – 404Combined sources5
Helixi410 – 415Combined sources6
Helixi420 – 422Combined sources3
Helixi425 – 438Combined sources14
Turni443 – 445Combined sources3
Helixi450 – 460Combined sources11
Beta strandi464 – 466Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AQFX-ray3.10A/B/C1-482[»]
4AQGX-ray2.80A1-482[»]
SMRiP89522.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.

Sequencei

Sequence statusi: Complete.

P89522-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKIEVNNK DEMNRWFEEF KKGNGLVDTF TNSYSFCESV PNLDRFVFQM
60 70 80 90 100
ASATDDAQKD SIYASALVEA TKFCAPIYEC AWVSSTGIVK KGLEWFEKNA
110 120 130 140 150
GTIKSWDESY TELKVDVPKI EQLTGYQQAA LKWRKDIGFR VNANTAALSN
160 170 180 190 200
KVLAEYKVPG EIVMSVKEML SDMIRRRNLI LNRGGDENPR GPVSHEHVDW
210 220 230 240 250
CREFVKGKYI MAFNPPWGDI NKSGRSGIAL VATGLAKLAE TEGKGIFDEA
260 270 280 290 300
KKTVEALNGY LDKHKDEVDR ASADSMITNL LKHIAKAQEL YKNSSALRAQ
310 320 330 340 350
SAQIDTAFSS YYWLYKAGVT PETFPTVSQF LFELGKQPRG TKKMKKALLS
360 370 380 390 400
TPMKWGKKLY ELFADDSFQQ NRIYMHPAVL TAGRISEMGV CFGTIPVANP
410 420 430 440 450
DDAAQGSGHT KSILNLRTNT ETNNPCAKTI VKLFEVQKTG FNIQDMDIVA
460 470 480
SEHLLHQSLV GKQSPFQNAY NVKGNATSAN II
Length:482
Mass (Da):53,891
Last modified:May 1, 1997 - v1
Checksum:i3E37B8A17F1B8F5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88410 Genomic RNA. Translation: AAB48501.1.
RefSeqiNP_950237.1. NC_005302.1.

Genome annotation databases

GeneIDi2943076.
KEGGivg:2943076.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88410 Genomic RNA. Translation: AAB48501.1.
RefSeqiNP_950237.1. NC_005302.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AQFX-ray3.10A/B/C1-482[»]
4AQGX-ray2.80A1-482[»]
SMRiP89522.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2943076.
KEGGivg:2943076.

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNCAP_CCHFI
AccessioniPrimary (citable) accession number: P89522
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: May 1, 1997
Last modified: November 30, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.