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Protein

Genome polyprotein

Gene
N/A
Organism
Turnip mosaic virus (strain Japanese) (TuMV)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
Nuclear inclusion protein B: an RNA-dependent RNA polymerase that plays an essential role in the virus replication.
Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity).By similarity
Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity).By similarity
Both 6K peptides are indispensable for virus replication.By similarity
Nuclear inclusion protein A: has RNA-binding and proteolytic activities.

Catalytic activityi

Hydrolyzes glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved.
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation
Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the potyviral polyprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei270For P1 proteinase activityBy similarity1
Active sitei279For P1 proteinase activitySequence analysis1
Active sitei313For P1 proteinase activityBy similarity1
Active sitei706For helper component proteinase activityPROSITE-ProRule annotation1
Active sitei779For helper component proteinase activityPROSITE-ProRule annotation1
Active sitei2162For nuclear inclusion protein A activityPROSITE-ProRule annotation1
Active sitei2197For nuclear inclusion protein A activityPROSITE-ProRule annotation1
Active sitei2267For nuclear inclusion protein A activityPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi1313 – 1320ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Suppressor of RNA silencing, Thiol protease, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 10 chains:
Alternative name(s):
N-terminal protein
Helper component proteinase (EC:3.4.22.45)
Short name:
HC-pro
6 kDa protein 1
Short name:
6K1
6 kDa protein 2
Short name:
6K2
Alternative name(s):
VPg
Nuclear inclusion protein A (EC:3.4.22.44)
Short name:
NI-a
Short name:
NIa
Alternative name(s):
49 kDa proteinase
Short name:
49 kDa-Pro
NIa-pro
Nuclear inclusion protein B (EC:2.7.7.48)
Short name:
NI-b
Short name:
NIb
Alternative name(s):
RNA-directed RNA polymerase
Capsid protein
Short name:
CP
Alternative name(s):
Coat protein
OrganismiTurnip mosaic virus (strain Japanese) (TuMV)
Taxonomic identifieri12230 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stagePotyviridaePotyvirus
Virus hostiAlliaria petiolata (Garlic mustard) (Arabis petiolata) [TaxID: 126270]
Brassica [TaxID: 3705]
Calanthe [TaxID: 38206]
Capsella bursa-pastoris (Shepherd's purse) (Thlaspi bursa-pastoris) [TaxID: 3719]
Hesperis matronalis [TaxID: 264418]
Stellaria media (Common chickweed) (Alsine media) [TaxID: 13274]
Trifolium hybridum (Alsike clover) [TaxID: 74517]
Proteomesi
  • UP000008262 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004200291 – 3164Genome polyproteinAdd BLAST3164
ChainiPRO_00000404631 – 362P1 proteinaseSequence analysisAdd BLAST362
ChainiPRO_0000040464363 – 820Helper component proteinaseSequence analysisAdd BLAST458
ChainiPRO_0000040465821 – 1175Protein P3By similarityAdd BLAST355
ChainiPRO_00000404661176 – 12276 kDa protein 1By similarityAdd BLAST52
ChainiPRO_00000404671228 – 1871Cytoplasmic inclusion proteinBy similarityAdd BLAST644
ChainiPRO_00000404681872 – 19246 kDa protein 2By similarityAdd BLAST53
ChainiPRO_00000404691925 – 2116Viral genome-linked proteinBy similarityAdd BLAST192
ChainiPRO_00000404702117 – 2359Nuclear inclusion protein ABy similarityAdd BLAST243
ChainiPRO_00000404712360 – 2876Nuclear inclusion protein BBy similarityAdd BLAST517
ChainiPRO_00000404722877 – 3164Capsid proteinBy similarityAdd BLAST288

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1987O-(5'-phospho-RNA)-tyrosineBy similarity1

Post-translational modificationi

VPg is uridylylated by the polymerase and is covalently attached to the 5'-end of the genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase (By similarity).By similarity
Potyviral RNA is expressed as two polyproteins which undergo post-translational proteolytic processing. Genome polyprotein is processed by NIa-pro, P1 and HC-pro proteinases resulting in the production of at least ten individual proteins. P3N-PIPO polyprotein is cleaved by P1 and HC-pro proteinases resulting in the production of three individual proteins. The P1 proteinase and the HC-pro cleave only their respective C-termini autocatalytically. 6K1 is essential for proper proteolytic separation of P3 from CI (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei362 – 363Cleavage; by P1 proteinaseSequence analysis2
Sitei820 – 821Cleavage; by autolysisPROSITE-ProRule annotation2
Sitei1175 – 1176Cleavage; by NIa-proBy similarity2
Sitei1227 – 1228Cleavage; by NIa-proBy similarity2
Sitei1871 – 1872Cleavage; by NIa-proBy similarity2
Sitei1924 – 1925Cleavage; by NIa-proBy similarity2
Sitei2116 – 2117Cleavage; by NIa-proBy similarity2
Sitei2359 – 2360Cleavage; by NIa-proBy similarity2
Sitei2876 – 2877Cleavage; by NIa-proBy similarity2

Keywords - PTMi

Covalent protein-RNA linkage, Phosphoprotein

Structurei

Secondary structure

13164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi708 – 714Combined sources7
Helixi715 – 717Combined sources3
Helixi720 – 722Combined sources3
Helixi723 – 732Combined sources10
Helixi734 – 738Combined sources5
Helixi744 – 757Combined sources14
Helixi759 – 763Combined sources5
Beta strandi768 – 772Combined sources5
Turni773 – 776Combined sources4
Beta strandi777 – 781Combined sources5
Beta strandi784 – 786Combined sources3
Beta strandi788 – 790Combined sources3
Helixi799 – 807Combined sources9
Beta strandi808 – 810Combined sources3
Helixi813 – 816Combined sources4
Beta strandi817 – 819Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RNVX-ray2.00A663-820[»]
ProteinModelPortaliP89509.
SMRiP89509.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini698 – 820Peptidase C6PROSITE-ProRule annotationAdd BLAST123
Domaini1300 – 1452Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST153
Domaini1471 – 1630Helicase C-terminalPROSITE-ProRule annotationAdd BLAST160
Domaini2117 – 2335Peptidase C4PROSITE-ProRule annotationAdd BLAST219
Domaini2601 – 2725RdRp catalyticPROSITE-ProRule annotationAdd BLAST125

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi414 – 417Involved in interaction with stylet and aphid transmissionBy similarity4
Motifi672 – 674Involved in virions binding and aphid transmissionBy similarity3
Motifi1402 – 1405DECH box4
Motifi1965 – 1972Nuclear localization signalSequence analysis8

Domaini

The N-terminus of helper component proteinase is involved in interaction with stylets. The central part is involved in interaction with virions and the C-terminus is involved in cell-to cell movement of the virus.

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation
Contains 1 peptidase C4 domain.PROSITE-ProRule annotation
Contains 1 peptidase C6 domain.PROSITE-ProRule annotationCurated
Contains 1 peptidase S30 domain.Curated
Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Genome polyprotein (identifier: P89509-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAAVTFATAI TNTTASKPAL TGMIQFGNFP PVPLRSTTVT TVATSVAQPK
60 70 80 90 100
LHTVQFGSLD PVVVKSGAGS FAKATRQQPN VEIDVSLSEA AALEVAKPRP
110 120 130 140 150
NAVLRMHEEA NKERALFLDW EASLKRSSYG IAENEKVVMT TRGVSKIVPR
160 170 180 190 200
SSGAMKQKRA RERRRAQQPI ILKWEPKLSG ISIGGGLSAS AIEVEEARTK
210 220 230 240 250
WPLHKTPSMK RKTVHRRCKM NDQGIDMLMR SLIKIFKAKS ANIEFIGRKS
260 270 280 290 300
IKVDFVKKEQ TKFARVQVVH LLGKRAQRDL STGMEENHFI DILSGYSGNK
310 320 330 340 350
TTINPGVVCA GWSGIVVRDG ILTQKRSRSP SEAFVIRGEH EGKLYDARIK
360 370 380 390 400
ITRTMSHKIV HFSAAGANFW KGFDRCFLAY RSDNREHTCY SGLDVTECGE
410 420 430 440 450
VAALMCLAMF PCGKITCPDC VTDSELSQGQ ASGPSMKHRL VQLRDVIKSS
460 470 480 490 500
YPRFKHAVQI LDRYEQSLRS ANENYQDFAE IQSISDGVEK AAFPHVNKLN
510 520 530 540 550
AILIKGATAT GEEFSQATKH LLEIARYLKN RTENIEKGSL KSFRNKISQK
560 570 580 590 600
AHINPTLMCD NQLDRNGNFI WGERGYHAKR FFSNYFEIID PKKGYTQYET
610 620 630 640 650
RVVPNGSRKL AIGKLIVPTN FEVLREQMKG EPVEPYPVTV ECVSKLQGDF
660 670 680 690 700
VHACCCVTTE SGDPVLSEIK MPTKHHLVIG NSGDPKYIDL PEIEENKMYI
710 720 730 740 750
AKEGYCYINI FLAMLVNVKE SQAKEFTKVV RDKLVGELGK WPTLLDVATA
760 770 780 790 800
CYFLKVFYPD VANAELPRML VDHKTKIIHV VDSYGSLSTG YHVLKTNTVE
810 820 830 840 850
QLIKFTRCNL ESSLKHYRVG GTEWEDTHGA KNIDDPQWCI KRLIKGVYRP
860 870 880 890 900
KQLKEDMLAN PFLPLYALLS PGVILAFYNS GSLEYLMNHY IRVDSNVAVL
910 920 930 940 950
LVVLKSLAKK VSTSQSVLAQ LQIIDRSLPE LVEARANINR PDDEAARACN
960 970 980 990 1000
RFMGMLLHMS EPNWELADGG YTILRDHSIS ILEKSYLQTL DEAWNELSWS
1010 1020 1030 1040 1050
ERCAIRYYSS KQAIFTQKDL PMRSEVDLGG RYSASVASSY EWSKQRVKSA
1060 1070 1080 1090 1100
YSRIGSRLRS GVSWTSSKVS NSVCRTINYL IPDVFRFINV LVCISLLVTI
1110 1120 1130 1140 1150
AAEANRIVTT QRRLKLDVEE TERRKIEWEL AFHHAILTQS AGQHPTIDEF
1160 1170 1180 1190 1200
STYIADKAPH LSEHIEPEEK VVVHQVKRQS EQELERIIAF VALVLMMFDA
1210 1220 1230 1240 1250
ERSDCVTKIL NKLKGLVATV EPTVYHQTLN DIEDDLSERN LFVDFELSSD
1260 1270 1280 1290 1300
GDMLQQLPTE KTFASWWNHQ LSRGFTIPHY RTEGKFMTFT RATATEVAGK
1310 1320 1330 1340 1350
IAHESDKDIL LMGAVGSGKS TGLPYHLSRK GNVLLLEPTR PLAENVHRQL
1360 1370 1380 1390 1400
SQAPFHQNTT LRMRGLTSFG SAPISVMTSG FALNYFANNR MRIEEFDFVI
1410 1420 1430 1440 1450
FDECHVHDAN AMAMRCLLHE CDYSGKIIKV SATPPGREVE FSTQYPVSIS
1460 1470 1480 1490 1500
TEDTLSFQDF VNAQGSGSNC DVISKGDNIL VYVASYNEVD ALSKLLTERD
1510 1520 1530 1540 1550
FKVTKVDGRT MKVGNIEITT SGTPSKKHFI VATNIIENGV TLDIDVVADF
1560 1570 1580 1590 1600
GTKVLPYLDT DSRMLSTTKT SINYGERIQR LGRVGRHKPG HALRIGHTEK
1610 1620 1630 1640 1650
GLSEVPSCIA TEAALKCFTY GLPVITNNVS TSILGNVTVK QARTMSVFEI
1660 1670 1680 1690 1700
TPFYTSQVVR YDGSMHPQVH ALLKRFKLRD SEIVLNKLAI PHRGVNAWLT
1710 1720 1730 1740 1750
ASEYARLGAN VEDRRDVRIP FMCRDIPEKL HLDMWDVIVK FKGDAGFGRL
1760 1770 1780 1790 1800
SSASASKVAY TLQTDVNSIQ RTVTIIDTLI AEERRKQEYF KTVTSNCVSS
1810 1820 1830 1840 1850
SNFSLQSITN AIKSRMMKDH TCENISVLEG AKSQLLEFRN LNADHSFATK
1860 1870 1880 1890 1900
TDGISQHFMS EYGALEAVHH QNTSDLSKFL KLKGKWNKTL ITRDVLVLCG
1910 1920 1930 1940 1950
VLGGGLWMVI QHLRSKISEP VTHEAKGKRQ RQKLKFRSIR DNKMGREVYG
1960 1970 1980 1990 2000
DDDTIEHFFG DAYTKKGKSK GRTRGLGHKN RKFINMYGFD PEDFSAVRFV
2010 2020 2030 2040 2050
DPLTGATLDD NPFTDIALVQ EHFGNIRMDL LGEDELDPNE VRMNKTIQAY
2060 2070 2080 2090 2100
YMNNKTGKAL KVDLTPHIPL KVCDLHATIA GFPERENELR QTGKAQPINI
2110 2120 2130 2140 2150
DEVPRANNEL VPVDHESNSM FRGLRDYNPI SNNICHLTNV SDGASNSLYG
2160 2170 2180 2190 2200
VGFGPLILTN RHLFERNNGE LIIKSRHGEF VIKNTTQLHL LPIPDRDLLL
2210 2220 2230 2240 2250
IRLPKDVPPF PQKLGFRQPE KGERICMVGS NFQTKSITSI VSETSTIMPV
2260 2270 2280 2290 2300
ENSQFWKHWI STKDGQCGSP MVSTKDGKIL GLHSLANFQN SINYFAAFPD
2310 2320 2330 2340 2350
DFAEKYLHTI EAHEWVKHWK YNTSAISWGA LNIQASQPSG LFKVSKLISD
2360 2370 2380 2390 2400
LDSTAVYAQT QQNRWMFEQL NGNLKAIAHC PSQLVTKHTV KGKCQMFDLY
2410 2420 2430 2440 2450
LKLHDEAREY FQPMLGQYQK SKLNREAYAK DLLKYATPIE AGNIDCDLFE
2460 2470 2480 2490 2500
KTVEIVISDL RGYGFETCNY VTDENDIFEA LNMKSAVGAL YKGKKKDYFA
2510 2520 2530 2540 2550
EFTPEMKEEI LKQSCERLFL GKMGVWNGSL KAELRPLEKV EANKTRTFTA
2560 2570 2580 2590 2600
APLDTLLGGK VCVDDFNNQF YDHNLRAPWS VGMTKFYCGW DRLLESLPDG
2610 2620 2630 2640 2650
WVYCDADGSQ FDSSLSPYLI NAILNIRLGF MEEWDVGEVM LRNLYTEIVY
2660 2670 2680 2690 2700
TPISTPDGTL VKKFKGNNSG QPSTVVDNTL MVILAVNYSL KKSGIPSELR
2710 2720 2730 2740 2750
DSIIRFFVNG DDLLLSVHPE YEYILDTMAD NFRELGLKYT FDSRTREKGD
2760 2770 2780 2790 2800
LWFMSHQGHK REGIWIPKLE PERIVSILEW DRSKEPCHRL EAICAAMIES
2810 2820 2830 2840 2850
WGYDKLTHEI RKFYAWMIEQ APFSSLAQEG KAPYIAETAL RKLYLDKEPA
2860 2870 2880 2890 2900
QEDLTHYLQA IFEDYEDGTE ACVYHQAGET LDAGLTDEQK QAEKEKKERE
2910 2920 2930 2940 2950
KAEKERERQR QLALKKGKNA AQEEGERDNE VNAGTSGTFS VPRLKSLTSK
2960 2970 2980 2990 3000
MRVPRYEQRV ALNLDHLILY TPEQTDLSNT RSTRKQFDTW FEGVMADYEL
3010 3020 3030 3040 3050
TEDKMQIILN GLMVWCIENG TSPNINGMWV MMDGDDQVEF PIKPLIDHAK
3060 3070 3080 3090 3100
PTFRQIMAHF SDVAEAYIEK RNQDRPYMPR YGLQRNLTDM SLARYAFDFY
3110 3120 3130 3140 3150
EMTSRTPIRA REAHIQMKAA ALRGANNNLF GLDGNVGTTV ENTERHTTED
3160
VNRNMHNGLG VKGL
Note: Produced by conventional translation.
Length:3,164
Mass (Da):357,737
Last modified:May 1, 1997 - v1
Checksum:i0DFC735CB3A5231F
GO
Isoform P3N-PIPO polyprotein (identifier: P0CK11-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P0CK11.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by -1 ribosomal frameshifting in P3 ORF.
Length:1,043
Mass (Da):117,285
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83184 Genomic RNA. Translation: BAA11836.1.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83184 Genomic RNA. Translation: BAA11836.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RNVX-ray2.00A663-820[»]
ProteinModelPortaliP89509.
SMRiP89509.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPOLG_TUMVJ
AccessioniPrimary (citable) accession number: P89509
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 1, 1997
Last modified: November 2, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.