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Protein

Replication enhancer

Gene

AC3

Organism
Sida golden mosaic Honduras virus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enhances infectivity and symptom expression.UniRule annotation
Increases viral DNA accumulation.UniRule annotation

GO - Biological processi

Keywordsi

Biological processHost-virus interactionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancerUniRule annotation
Short name:
REnUniRule annotation
Gene namesi
Name:AC3Imported
OrganismiSida golden mosaic Honduras virusImported
Taxonomic identifieri223316 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the geminiviridae replication enhancer protein family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR000657. Gemini_AL3.
PfamiView protein in Pfam
PF01407. Gemini_AL3. 1 hit.
PRINTSiPR00231. GEMCOATAL3.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001172. Gemini_AL3. 1 hit.

Sequencei

Sequence statusi: Complete.

P89124-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRTGELIT VHQAENGVYT WEIENPLYFT MFLVEDPIYT NSRVYNIQIR
60 70 80 90 100
FNHNLRKALH LHKAFLNFQV WTISITASGS TYLARFRRLV NMYLDQLGVI
110 120 130
CINNVIRAVR FATDRFYVTR VLENHSIKFK IY
Length:132
Mass (Da):15,696
Last modified:May 1, 1997 - v1
Checksum:i040E541C959A8668
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11097 Genomic DNA. Translation: CAA71975.1.
RefSeqiNP_808895.1. NC_004659.1.

Genome annotation databases

GeneIDi988177.
KEGGivg:988177.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiP89124_9GEMI
AccessioniPrimary (citable) accession number: P89124
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: June 7, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)