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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.SAAS annotation

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

P88151-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIRA WNSLVKHHMY SSKKAAKWFY RHHYESQHPK
60 70 80 90
VSSEVHIPLG DARLIIRTYW GLHTGEKDWH LGHGVSIEWR QRK
Length:93
Mass (Da):11,429
Last modified:May 1, 1997 - v1
Checksum:i52C596E330C56460
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51188 Genomic DNA. Translation: AAB38825.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51188 Genomic DNA. Translation: AAB38825.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.
ProtoNetiSearch...

Publicationsi

  1. "The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin."
    Gao F., Robertson D.L., Morrison S.G., Hui H., Craig S., Decker J., Fultz P.N., Girard M., Shaw G.M., Hahn B.H., Sharp P.M.
    J. Virol. 70:7013-7029(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP88151_9HIV1
AccessioniPrimary (citable) accession number: P88151
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.