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Protein

Protein lsb5

Gene

lsb5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Endocytosis

Names & Taxonomyi

Protein namesi
Recommended name:
Protein lsb5
Gene namesi
Name:lsb5
ORF Names:SPBC31F10.07
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC31F10.07.
PomBaseiSPBC31F10.07. lsb5.

Subcellular locationi

GO - Cellular componenti

  • actin cortical patch Source: PomBase
  • cell cortex Source: PomBase
  • mitotic spindle pole body Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304Protein lsb5PRO_0000315965Add
BLAST

Proteomic databases

MaxQBiP87308.

Interactioni

Protein-protein interaction databases

BioGridi276857. 32 interactions.
MINTiMINT-4693111.

Structurei

3D structure databases

ProteinModelPortaliP87308.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 149130VHSPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi248 – 28336Ser-richAdd
BLAST

Sequence similaritiesi

Belongs to the LSB5 family.Curated
Contains 1 VHS domain.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiP87308.
OMAiPADESIF.
OrthoDBiEOG092C30PV.
PhylomeDBiP87308.

Family and domain databases

Gene3Di1.20.58.160. 1 hit.
1.25.40.90. 1 hit.
InterProiIPR008942. ENTH_VHS.
IPR004152. GAT_dom.
IPR002014. VHS_dom.
[Graphical view]
PfamiPF00790. VHS. 1 hit.
[Graphical view]
SMARTiSM00288. VHS. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50179. VHS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P87308-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIFSETVPI TAVTTYIDRL TSRDTDDEDL SGIVQLSEAV NLTVTGPREA
60 70 80 90 100
SRTLRKKLKY STPHEQVRAL VILQALIENA GSHFLQNFSD EKLEDRMLQC
110 120 130 140 150
ATNSEYSKPV RKRAIHMIKL WHNDYSNVRG MESMSSLVSR LPQRQSSASH
160 170 180 190 200
SEQPTINLKK VGPILERLIA SSSMAATNLS NSLVRINPNT ENPAKNKQIM
210 220 230 240 250
VYYVDCKRAH RSLLRYIQAI QDEMWLANLL KANDEIVTAI DAFKEKCSEN
260 270 280 290 300
SDYSSDSGSY SSSYSRHLDD RASYISRSSS GGSNAQRSED LDVNNPFGDH

NRLE
Length:304
Mass (Da):34,195
Last modified:July 1, 1997 - v1
Checksum:iE703692C9D5584A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB10084.1.
PIRiT40210.
RefSeqiNP_596569.1. NM_001022490.2.

Genome annotation databases

EnsemblFungiiSPBC31F10.07.1; SPBC31F10.07.1:pep; SPBC31F10.07.
GeneIDi2540327.
KEGGispo:SPBC31F10.07.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB10084.1.
PIRiT40210.
RefSeqiNP_596569.1. NM_001022490.2.

3D structure databases

ProteinModelPortaliP87308.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276857. 32 interactions.
MINTiMINT-4693111.

Proteomic databases

MaxQBiP87308.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC31F10.07.1; SPBC31F10.07.1:pep; SPBC31F10.07.
GeneIDi2540327.
KEGGispo:SPBC31F10.07.

Organism-specific databases

EuPathDBiFungiDB:SPBC31F10.07.
PomBaseiSPBC31F10.07. lsb5.

Phylogenomic databases

InParanoidiP87308.
OMAiPADESIF.
OrthoDBiEOG092C30PV.
PhylomeDBiP87308.

Miscellaneous databases

PROiP87308.

Family and domain databases

Gene3Di1.20.58.160. 1 hit.
1.25.40.90. 1 hit.
InterProiIPR008942. ENTH_VHS.
IPR004152. GAT_dom.
IPR002014. VHS_dom.
[Graphical view]
PfamiPF00790. VHS. 1 hit.
[Graphical view]
SMARTiSM00288. VHS. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50179. VHS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLSB5_SCHPO
AccessioniPrimary (citable) accession number: P87308
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 1, 1997
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.