Reviewed,
UniProtKB/Swiss-Prot P87284 (PMP3_YEAST)
Last modified
November 3, 2009.
Version 69.
History...
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90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Plasma membrane proteolipid 3 | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 55 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Plays a role in the regulation of membrane potential. Could mediate a proton leak. |
| Subcellular location | Cell membrane; Multi-pass membrane protein Potential. |
| Sequence similarities | Belongs to the UPF0057 (PMP3) family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | cation transport Ref.1 Inferred from mutant phenotype. Source: SGD regulation of membrane potential Ref.1Inferred from mutant phenotype. Source: SGD |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Ref.1Inferred from direct assay. Source: SGD |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Binary interactions
Sequence annotation (Features)
Sequences
References
| « Hide 'large scale' references | |
| [1] | "Membrane hyperpolarization and salt sensitivity induced by deletion of PMP3, a highly conserved small protein of yeast plasma membrane." Navarre C., Goffeau A. EMBO J. 19:2515-2524(2000) [PubMed: 10835350] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-25, CHARACTERIZATION, SUBCELLULAR LOCATION. Strain: ATCC 201238 / W303-1B. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.  Zaccaria P.Nature 387:75-78(1997) [PubMed: 9169867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J.Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| X91499 Genomic DNA. Translation: CAA62799.1. U51030 Genomic DNA. Translation: AAB64465.1. AY557718 Genomic DNA. Translation: AAS56044.1. | |
| PIR | S70224. |
| RefSeq | NP_010562.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:7280N. |
| IntAct | P87284. 160 interactions. |
| STRING | P87284. |
Protein family/group databases | |
| TCDB | 9.B.12.1.2. (Salt or low Temperature) stress-induced hydrophobic peptide (SHP) family. |
Genome annotation databases | |
| Ensembl | YDR276C; YDR276C; YDR276C; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 851869. |
| GenomeReviews | Gene locus YDR276C in contig Z71256_GR. |
| KEGG | sce:YDR276C. |
| NMPDR | fig|4932.3.peg.1324. |
Organism-specific databases | |
| CYGD | YDR276c. |
| SGD | S000002684. PMP3. |
Phylogenomic databases | |
| HOGENOM | P87284. |
| OMA | GMLYALY. |
Gene expression databases | |
| ArrayExpress | P87284. |
| Genevestigator | P87284. |
| GermOnline | YDR276C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR000612. UPF0057. [Graphical view] |
| PANTHER | PTHR21659. UPF0057. 1 hit. |
| Pfam | PF01679. UPF0057. 1 hit. [Graphical view] |
| PROSITE | PS01309. UPF0057. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 969818. |
Entry information
| Entry name | PMP3_YEAST | ||||||||
| Accession | Primary (citable) accession number: P87284 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Uncharacterized protein families (UPF) List of uncharacterized protein family (UPF) entries |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
