P87262 (RL34A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosomal protein L34-A

Gene names

Name:	RPL34A
Ordered Locus Names:	YER056C-A
ORF Names:	YER056BC

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.4.
Miscellaneous	Present with 23600 molecules/cell in log phase SD medium. There are 2 genes for L34 in yeast.
Sequence similarities	Belongs to the ribosomal protein L34e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Traceable author statement Ref.3. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Traceable author statement Ref.3. Source: SGD
Molecular_function	structural constituent of ribosome Traceable author statement Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 121	121	60S ribosomal protein L34-A		PRO_0000131845

Sequences

	Sequence		Length	Mass (Da)
	P87262 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: F3315816CD85ACEA	FASTA	121	13,639
	10 20 30 40 50 60 MAQRVTFRRR NPYNTRSNKI KVVKTPGGIL RAQHVKKLAT RPKCGDCGSA LQGISTLRPR 70 80 90 100 110 120 QYATVSKTHK TVSRAYGGSR CANCVKERII RAFLIEEQKI VKKVVKEQTE AAKKSEKKAK K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W. Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U18813 Genomic DNA. Translation: AAB64609.1.
BK006939 Genomic DNA. Translation: DAA07714.1.

PIR

S53549.

RefSeq

NP_010977.2. NM_001180036.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IZS	electron microscopy	-	i	1-118	[»]
3U5E	X-ray	3.00	g	1-121	[»]
3U5I	X-ray	3.00	g	1-121	[»]
4B6A	electron microscopy	8.10	g	1-121	[»]

ProteinModelPortal

P87262.

SMR

P87262. Positions 2-113.

ModBase

Search...

Protein-protein interaction databases

IntAct

P87262. 9 interactions.

MINT

MINT-1326013.

STRING

4932.YER056C-A.

Proteomic databases

PaxDb

P87262.

PRIDE

P87262.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YER056C-A; YER056C-A; YER056C-A.

GeneID

856784.

KEGG

sce:YER056C-A.

Organism-specific databases

CYGD

YER056c-a.

SGD

S000002135. RPL34A.

Phylogenomic databases

eggNOG

COG2174.

GeneTree

ENSGT00390000008294.

HOGENOM

HOG000216922.

KO

K02915.

OMA

SERPRMC.

OrthoDB

EOG4QG0PT.

Gene expression databases

Genevestigator

P87262.

GermOnline

YER056C-A. Saccharomyces cerevisiae.

Family and domain databases

InterPro

IPR008195. Ribosomal_L34Ae.
IPR018065. Ribosomal_L34e_CS.
[Graphical view]

PANTHER

PTHR10759. PTHR10759. 1 hit.

Pfam

PF01199. Ribosomal_L34e. 1 hit.
[Graphical view]

PRINTS

PR01250. RIBOSOMALL34.

PROSITE

PS01145. RIBOSOMAL_L34E. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

983000.

Entry information

Entry name

RL34A_YEAST

Accession

Primary (citable) accession number: P87262
Secondary accession number(s): D3DLW0, Q03189

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	July 1, 1997
Last modified:	April 3, 2013
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program