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P87262

- RL34A_YEAST

UniProt

P87262 - RL34A_YEAST

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Protein

60S ribosomal protein L34-A

Gene

RPL34A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. cytoplasmic translation Source: SGD
  2. ribosome biogenesis Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30350-MONOMER.
ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L34-A
Gene namesi
Name:RPL34A
Ordered Locus Names:YER056C-A
ORF Names:YER056BC
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER056c-a.
SGDiS000002135. RPL34A.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. preribosome, large subunit precursor Source: SGD
  2. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12112160S ribosomal protein L34-APRO_0000131845Add
BLAST

Proteomic databases

MaxQBiP87262.
PaxDbiP87262.
PRIDEiP87262.

Expressioni

Gene expression databases

GenevestigatoriP87262.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi36797. 30 interactions.
IntActiP87262. 13 interactions.
MINTiMINT-8285618.
STRINGi4932.YER056C-A.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VW8electron microscopy6.10h1-121[»]
1VWUelectron microscopy6.10h1-121[»]
1VXVelectron microscopy6.20h1-121[»]
1VXYelectron microscopy6.30h1-121[»]
3IZSelectron microscopy-i1-118[»]
3J65electron microscopy8.70f1-121[»]
3U5EX-ray3.00g1-121[»]
3U5IX-ray3.00g1-121[»]
4B6Aelectron microscopy8.10g1-121[»]
4BYNelectron microscopy4.30g2-121[»]
4BYUelectron microscopy6.60g2-121[»]
4CUWelectron microscopy3.70g1-121[»]
ProteinModelPortaliP87262.
SMRiP87262. Positions 2-113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L34e family.Curated

Phylogenomic databases

eggNOGiCOG2174.
GeneTreeiENSGT00390000008294.
HOGENOMiHOG000216922.
InParanoidiP87262.
KOiK02915.
OMAiSERPRMC.
OrthoDBiEOG76TB4F.

Family and domain databases

InterProiIPR008195. Ribosomal_L34Ae.
IPR018065. Ribosomal_L34e_CS.
[Graphical view]
PANTHERiPTHR10759. PTHR10759. 1 hit.
PfamiPF01199. Ribosomal_L34e. 1 hit.
[Graphical view]
PRINTSiPR01250. RIBOSOMALL34.
PROSITEiPS01145. RIBOSOMAL_L34E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P87262 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQRVTFRRR NPYNTRSNKI KVVKTPGGIL RAQHVKKLAT RPKCGDCGSA
60 70 80 90 100
LQGISTLRPR QYATVSKTHK TVSRAYGGSR CANCVKERII RAFLIEEQKI
110 120
VKKVVKEQTE AAKKSEKKAK K
Length:121
Mass (Da):13,639
Last modified:July 1, 1997 - v1
Checksum:iF3315816CD85ACEA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18813 Genomic DNA. Translation: AAB64609.1.
BK006939 Genomic DNA. Translation: DAA07714.1.
PIRiS53549.
RefSeqiNP_010977.2. NM_001180036.1.

Genome annotation databases

EnsemblFungiiYER056C-A; YER056C-A; YER056C-A.
GeneIDi856784.
KEGGisce:YER056C-A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18813 Genomic DNA. Translation: AAB64609.1 .
BK006939 Genomic DNA. Translation: DAA07714.1 .
PIRi S53549.
RefSeqi NP_010977.2. NM_001180036.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VW8 electron microscopy 6.10 h 1-121 [» ]
1VWU electron microscopy 6.10 h 1-121 [» ]
1VXV electron microscopy 6.20 h 1-121 [» ]
1VXY electron microscopy 6.30 h 1-121 [» ]
3IZS electron microscopy - i 1-118 [» ]
3J65 electron microscopy 8.70 f 1-121 [» ]
3U5E X-ray 3.00 g 1-121 [» ]
3U5I X-ray 3.00 g 1-121 [» ]
4B6A electron microscopy 8.10 g 1-121 [» ]
4BYN electron microscopy 4.30 g 2-121 [» ]
4BYU electron microscopy 6.60 g 2-121 [» ]
4CUW electron microscopy 3.70 g 1-121 [» ]
ProteinModelPortali P87262.
SMRi P87262. Positions 2-113.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36797. 30 interactions.
IntActi P87262. 13 interactions.
MINTi MINT-8285618.
STRINGi 4932.YER056C-A.

Proteomic databases

MaxQBi P87262.
PaxDbi P87262.
PRIDEi P87262.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER056C-A ; YER056C-A ; YER056C-A .
GeneIDi 856784.
KEGGi sce:YER056C-A.

Organism-specific databases

CYGDi YER056c-a.
SGDi S000002135. RPL34A.

Phylogenomic databases

eggNOGi COG2174.
GeneTreei ENSGT00390000008294.
HOGENOMi HOG000216922.
InParanoidi P87262.
KOi K02915.
OMAi SERPRMC.
OrthoDBi EOG76TB4F.

Enzyme and pathway databases

BioCyci YEAST:G3O-30350-MONOMER.
Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Miscellaneous databases

NextBioi 983000.

Gene expression databases

Genevestigatori P87262.

Family and domain databases

InterProi IPR008195. Ribosomal_L34Ae.
IPR018065. Ribosomal_L34e_CS.
[Graphical view ]
PANTHERi PTHR10759. PTHR10759. 1 hit.
Pfami PF01199. Ribosomal_L34e. 1 hit.
[Graphical view ]
PRINTSi PR01250. RIBOSOMALL34.
PROSITEi PS01145. RIBOSOMAL_L34E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
    Planta R.J., Mager W.H.
    Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, SUBUNIT.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Crystal structure of the eukaryotic ribosome."
    Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
    Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
  7. Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.

Entry informationi

Entry nameiRL34A_YEAST
AccessioniPrimary (citable) accession number: P87262
Secondary accession number(s): D3DLW0, Q03189
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: October 29, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 23600 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for L34 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3