Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P87218 (SOU2_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sorbose reductase homolog SOU2

EC=1.1.-.-
Gene names
Name:SOU2
ORF Names:CaO19.10415, CaO19.2897
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Unknown. The enzyme has no activity toward sorbose.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Sorbose reductase homolog SOU2
PRO_0000054778

Regions

Nucleotide binding41 – 6323NAD By similarity

Sites

Active site1881Proton acceptor By similarity
Binding site1731Substrate By similarity

Natural variations

Natural variant129 – 1302EI → KF in strain: SOR17.
Natural variant1911A → R in strain: SOR17.
Natural variant202 – 2032LS → FT in strain: SOR17.
Natural variant2801V → I in strain: SOR17.

Sequences

Sequence LengthMass (Da)Tools
P87218 [UniParc].

Last modified January 24, 2006. Version 2.
Checksum: ABFA091C75A3D297

FASTA28029,878
        10         20         30         40         50         60 
MSKETTSYTN AKLGPLPTKA ATIPDNILDA FSLKGKVASV TGSSGGIGWA VAEGYAQAGA 

        70         80         90        100        110        120 
DVAIWYNSHP ADDKAEYLTK TYGVKSKAYK CNVTDFQDVE KVVKQIESDF GTIDIFVANA 

       130        140        150        160        170        180 
GVAWTEGPEI DVKGVDKWNK VVDVDLNSVY YCAHVVGPIF RKKGKGSFIF TASMSASIVN 

       190        200        210        220        230        240 
VPQLQAAYNA AKAGVKHLSK SLSVEWAPFA RVNSVSPGYI ATHLSEFADP DVKSKWLQLT 

       250        260        270        280 
PLGREAKPRE LVGAYLYLAS DAASYTTGAD LAVDGGYTVV 

« Hide

References

« Hide 'large scale' references
[1]"Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans."
Janbon G., Sherman F., Rustchenko E.
Proc. Natl. Acad. Sci. U.S.A. 95:5150-5155(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SOR17.
[2]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF002134 Genomic DNA. Translation: AAC24462.1.
AACQ01000084 Genomic DNA. Translation: EAK96530.1.
AACQ01000083 Genomic DNA. Translation: EAK96589.1.
RefSeqXP_715553.1. XM_710460.1.
XP_715609.1. XM_710516.1.

3D structure databases

ProteinModelPortalP87218.
SMRP87218. Positions 4-278.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0005254.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3642759.
3642823.
KEGGcal:CaO19.10415.
cal:CaO19.2897.

Organism-specific databases

CGDCAL0005254. SOU2.

Phylogenomic databases

eggNOGCOG1028.
OrthoDBEOG7HQNM0.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSOU2_CANAL
AccessionPrimary (citable) accession number: P87218
Secondary accession number(s): Q5A1C2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 24, 2006
Last modified: November 13, 2013
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names