Reviewed, UniProtKB/Swiss-Prot P87207 (MNT3_CANAL)

Names and origin

Protein names

Recommended name:
    Probable mannosyltransferase MNT3
    EC=2.4.1.131

Gene names

Name:	MNT3
ORF Names:	CaO19.8624

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
Subcellular location	Membrane; Single-pass type II membrane protein Potential.
Sequence similarities	Belongs to the glycosyltransferase 15 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal-anchor Transmembrane
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	protein amino acid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glycolipid 2-alpha-mannosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 378	378	Probable mannosyltransferase MNT3		PRO_0000208249
Regions
	Topological domain	1 – 4	4	Cytoplasmic Potential
	Transmembrane	5 – 25	21	Signal-anchor for type II membrane protein Potential
	Topological domain	26 – 378	353	Lumenal Potential
Amino acid modifications
	Glycosylation	73	1	N-linked (GlcNAc...) Potential
	Glycosylation	149	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P87207-1 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 8583380E66FD64BC	FASTA	378	45,300
	10 20 30 40 50 60 MLRHLVFILI AILLLTFPPK IESLFKSFII NKPTKTTCYQ YTTREQLKSI LESDIHETNF 70 80 90 100 110 120 CIEKPSTSPP KTNSTLLMLC QNSDIFSVLE TIQNIQDRFN DKYNYDYTFL NDVPFNYEFI 130 140 150 160 170 180 YLVSSIIPHG KINFGLIPIE HWSYPSHINI SLATEIRQNY ANVPYGDSES YRHMCRFYSG 190 200 210 220 230 240 FFYKHELVKQ YQYYWRIEPG IKIYCDIDYD VFEYMIINDK KYGFVISLFE YSETIPTLWN 250 260 270 280 290 300 HVVQYINDNE IKSELLPLLT NKYNWYNLCH FWSNFEIANL DIFNNDDYEN FFQYLDNLGG 310 320 330 340 350 360 FYYERWGDAP IHSIAIALFL QKKDIHWFEN IGYYHVPYLQ CPQDIDLYVK NKCTCNPDED 370 FTWSDLSCTN HFLNILHN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Buurman E.T., Gow N.A.R. Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SGY243.
[2]	"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y13642 Genomic DNA. Translation: CAA73985.1. AACQ01000293 Genomic DNA. Translation: EAK91002.1.
RefSeq	XP_710267.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT15. Glycosyltransferase Family 15.
Genome annotation databases
GeneID	3648130.
Organism-specific databases
CGD	CAL0069886. MNT3.
Enzyme and pathway databases
BRENDA	2.4.1.131. 1124.
Family and domain databases
InterPro	IPR002685. Glyco_trans_15. [Graphical view]
Pfam	PF01793. Glyco_transf_15. 1 hit. [Graphical view]
PIRSF	PIRSF018153. Glyco_trans_15. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MNT3_CANAL

Accession

Primary (citable) accession number: P87207
Secondary accession number(s): Q59KJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	July 1, 1997
Last modified:	June 16, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)