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Protein

Uncharacterized WD repeat-containing protein C3D6.12

Gene

SPBC3D6.12

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-SPO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized WD repeat-containing protein C3D6.12
Gene namesi
ORF Names:SPBC3D6.12
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC3D6.12.
PomBaseiSPBC3D6.12.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • Pwp2p-containing subcomplex of 90S preribosome Source: GO_Central
  • small-subunit processome Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000514921 – 922Uncharacterized WD repeat-containing protein C3D6.12Add BLAST922

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei769Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP87177.
PRIDEiP87177.

PTM databases

iPTMnetiP87177.

Interactioni

Protein-protein interaction databases

BioGridi277487. 1 interactor.
MINTiMINT-4692781.

Structurei

3D structure databases

ProteinModelPortaliP87177.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati63 – 101WD 1Add BLAST39
Repeati102 – 141WD 2Add BLAST40
Repeati169 – 210WD 3Add BLAST42
Repeati213 – 252WD 4Add BLAST40
Repeati268 – 307WD 5Add BLAST40
Repeati336 – 377WD 6Add BLAST42
Repeati394 – 432WD 7Add BLAST39
Repeati434 – 472WD 8Add BLAST39
Repeati475 – 514WD 9Add BLAST40
Repeati532 – 571WD 10Add BLAST40
Repeati574 – 615WD 11Add BLAST42
Repeati616 – 655WD 12Add BLAST40
Repeati658 – 695WD 13Add BLAST38

Sequence similaritiesi

Belongs to the WD repeat WDR3/UTP12 family.Curated
Contains 13 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000212524.
InParanoidiP87177.
KOiK14556.
OMAiSYLKYEH.
OrthoDBiEOG092C0EL4.
PhylomeDBiP87177.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR007148. SSU_processome_Utp12.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF04003. Utp12. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 12 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 4 hits.
PROSITEiPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P87177-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKSYTRYEP TEFFGVIASS GCNILGQPSS SAKSVGRAIV GGLESVLEWD
60 70 80 90 100
LKTGQLLSKW KDSDCSAKVT CIANFDEMYA VGYADGSIRL WKDGELLITL
110 120 130 140 150
NGHKSAVTTM DFDKMGTRLA SGSMDTDIIV WDIVAETGLF RLRGHKDQIT
160 170 180 190 200
KLLFITPPSK NTAEETVVDT DIDSGDMDVD SKSSDSFLLS VGKDSFMKLW
210 220 230 240 250
DLSIQHCVET HVDHQGEIWA MCVSPDAKRC LTAGTGSDVK VWEISFPDDN
260 270 280 290 300
NFTPTTKAFQ QLGTFTRQSR DRPITLAYDV SNRYVVFQAH DRLLEVFRLR
310 320 330 340 350
SSAELEKILN RRRRRKKSED VSITLKDEYE PFALIRTTAR ASSVAWIPGN
360 370 380 390 400
RTPTLVTSLQ NNSIEVYALD VKSEGSAAPL TERASRISAI EIPGHRADVR
410 420 430 440 450
TLALSANHDV ILSGANGSLK LWNKKTTSCI RTIECGYVLA ASFINNDKCI
460 470 480 490 500
VSAYKSGELE VYDIASSSLI ERIQAHDGAI WDLAVGHDGT YFATASADHT
510 520 530 540 550
VKLWSLKSSF DFVPGTTRKV TTLKLEQTRQ IDFTDDVLAV KISPDGRFVA
560 570 580 590 600
ASLLDNTVKV YYLDSLKFFL NLYGHKLPVL SMDISYDSKL LVTCSADKNV
610 620 630 640 650
KIWGLDFGDC HKSIFAHQDS IMEVTFQPDT YNFFTCSKDR EVRYWDGKSF
660 670 680 690 700
DLILKLRGHH SEVWALAVGP TFVVSGSHDH SIRLWEQGDD LVFLEEERER
710 720 730 740 750
ELEEQYESTL VSSYENAEAD GEVKDGDVAA VTKQTIESLK DGEKILEAIT
760 770 780 790 800
IGIEDLDQEI QYRLDLLKSP GKARGPRNPI LAHLGVSAEE YVLNTFKKIR
810 820 830 840 850
SSHLDDALLV LPFEHVLSLF RFIDIWASRK WSIPLVSRII FFLLRTYHRQ
860 870 880 890 900
LTTTVKMRPL LNNIRSSLRG SLQEERSLIG YNAAGLSYLR HEWELTHNTS
910 920
LEDIDSTSLE VDGKKRAFSN IV
Length:922
Mass (Da):103,428
Last modified:July 1, 1997 - v1
Checksum:i578C01A1D71162C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB09121.1.
PIRiT40372.
RefSeqiNP_595524.1. NM_001021433.2.

Genome annotation databases

EnsemblFungiiSPBC3D6.12.1; SPBC3D6.12.1:pep; SPBC3D6.12.
GeneIDi2540971.
KEGGispo:SPBC3D6.12.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB09121.1.
PIRiT40372.
RefSeqiNP_595524.1. NM_001021433.2.

3D structure databases

ProteinModelPortaliP87177.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277487. 1 interactor.
MINTiMINT-4692781.

PTM databases

iPTMnetiP87177.

Proteomic databases

MaxQBiP87177.
PRIDEiP87177.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC3D6.12.1; SPBC3D6.12.1:pep; SPBC3D6.12.
GeneIDi2540971.
KEGGispo:SPBC3D6.12.

Organism-specific databases

EuPathDBiFungiDB:SPBC3D6.12.
PomBaseiSPBC3D6.12.

Phylogenomic databases

HOGENOMiHOG000212524.
InParanoidiP87177.
KOiK14556.
OMAiSYLKYEH.
OrthoDBiEOG092C0EL4.
PhylomeDBiP87177.

Enzyme and pathway databases

ReactomeiR-SPO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Miscellaneous databases

PROiP87177.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR007148. SSU_processome_Utp12.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF04003. Utp12. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 12 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 4 hits.
PROSITEiPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYB1C_SCHPO
AccessioniPrimary (citable) accession number: P87177
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.