P87172 (GPI3_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 68.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit EC=2.4.1.198 Alternative name(s): GlcNAc-PI synthesis protein | ||||
| Gene names |
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| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ||||
| Taxonomic identifier | 284812 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 456 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis By similarity. |
| Catalytic activity | UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol. |
| Pathway | Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. |
| Subunit structure | Component of a Phosphatidylinositol N-acetylglucosaminyltransferase complex By similarity. |
| Sequence similarities | Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | GPI-anchor biosynthesis |
| Molecular function | Glycosyltransferase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | GPI anchor biosynthetic process Inferred from sequence or structural similarity. Source: GeneDB_Spombe |
| Cellular component | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex Inferred from sequence or structural similarity. Source: GeneDB_Spombe |
| Molecular function | phosphatidylinositol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 456 | 456 | Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit | PRO_0000339138 | |||
Sequences
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References
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU329671 Genomic DNA. Translation: CAB09127.1. |
| PIR | T40367. |
| RefSeq | NP_595519.1. NM_001021428.1. |
3D structure databases | |
| ProteinModelPortal | P87172. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P87172. |
Protein family/group databases | |
| CAZy | GT4. Glycosyltransferase Family 4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPBC3D6.07.1; SPBC3D6.07.1:pep; SPBC3D6.07. |
| GeneID | 2540986. |
| GenomeReviews | Gene locus gpi3 in contig CU329671_GR. |
| KEGG | spo:SPBC3D6.07. |
| NMPDR | fig|4896.1.peg.1385. |
Organism-specific databases | |
| GeneDB_Spombe | SPBC3D6.07. |
Phylogenomic databases | |
| eggNOG | fuNOG06031. |
| GeneTree | EFGT00050000006418. |
| HOGENOM | HBG315887. |
| OMA | VKQMYSW. |
| OrthoDB | EOG4FR417. |
Gene expression databases | |
| ArrayExpress | P87172. |
Family and domain databases | |
| InterPro | IPR001296. Glyco_trans_1. IPR013234. PIGA_GPI_anchor_biosynthesis. [Graphical view] |
| KO | K03857. |
| Pfam | PF00534. Glycos_transf_1. 1 hit. PF08288. PIGA. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GPI3_SCHPO | ||||||||
| Accession | Primary (citable) accession number: P87172 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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