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Protein

40S ribosomal protein S4-A

Gene

rps401

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72649. Translation initiation complex formation.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SPO-72702. Ribosomal scanning and start codon recognition.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4-A
Gene namesi
Name:rps401
Synonyms:rps4, rps4a
ORF Names:SPBC19F8.08, SPBC25H2.17c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.08.
PomBaseiSPBC19F8.08. rps401.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • cytosolic small ribosomal subunit Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308391 – 26240S ribosomal protein S4-AAdd BLAST262

Proteomic databases

PRIDEiP87158.

Interactioni

Protein-protein interaction databases

BioGridi277174. 57 interactors.
MINTiMINT-4692696.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 105S4 RNA-bindingAdd BLAST64

Sequence similaritiesi

Belongs to the ribosomal protein S4e family.Curated
Contains 1 S4 RNA-binding domain.Curated

Phylogenomic databases

HOGENOMiHOG000231325.
InParanoidiP87158.
KOiK02987.
OMAiVITHREH.
OrthoDBiEOG092C443N.
PhylomeDBiP87158.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiIPR032277. 40S_S4_C.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P87158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRGPKKHLK RVAAPHHWLL DKLSGTYAPK PSPGPHKARE CLPLIVFLRN
60 70 80 90 100
RLKYALNGRE VKAILMQRLI KVDGKVRTDS TFPTGFMDVI SVEKTGEHFR
110 120 130 140 150
LVYDIKGRFT VHRITAEEAK YKLCKVKRVQ LGAKGVPFLV THDGRTIRYP
160 170 180 190 200
DPLIKVNDTI KLNLETNKIE SFIKFDTSAQ VMVTGGRNMG RVGTIVHREH
210 220 230 240 250
HLGSFEIIHV KDALDREFAT RLSNVFVIGE TGKSWISLPK GKGVKLSITE
260
ERDRRRALKG LA
Length:262
Mass (Da):29,689
Last modified:November 1, 1998 - v2
Checksum:iFBDCB5D1EB0537C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti9L → F in AAB63866 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19128.1.
U97374 mRNA. Translation: AAB63866.1.
PIRiT39831.
T40012.
RefSeqiNP_596350.1. NM_001022270.2.

Genome annotation databases

EnsemblFungiiSPBC19F8.08.1; SPBC19F8.08.1:pep; SPBC19F8.08.
GeneIDi2540649.
KEGGispo:SPBC19F8.08.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19128.1.
U97374 mRNA. Translation: AAB63866.1.
PIRiT39831.
T40012.
RefSeqiNP_596350.1. NM_001022270.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277174. 57 interactors.
MINTiMINT-4692696.

Proteomic databases

PRIDEiP87158.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC19F8.08.1; SPBC19F8.08.1:pep; SPBC19F8.08.
GeneIDi2540649.
KEGGispo:SPBC19F8.08.

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.08.
PomBaseiSPBC19F8.08. rps401.

Phylogenomic databases

HOGENOMiHOG000231325.
InParanoidiP87158.
KOiK02987.
OMAiVITHREH.
OrthoDBiEOG092C443N.
PhylomeDBiP87158.

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72649. Translation initiation complex formation.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SPO-72702. Ribosomal scanning and start codon recognition.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP87158.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiIPR032277. 40S_S4_C.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS4A_SCHPO
AccessioniPrimary (citable) accession number: P87158
Secondary accession number(s): O14378
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.