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Protein

40S ribosomal protein S4-A

Gene

rps401

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-SPO-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SPO-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SPO-72689 Formation of a pool of free 40S subunits
R-SPO-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-SPO-72702 Ribosomal scanning and start codon recognition
R-SPO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SPO-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SPO-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4-A
Gene namesi
Name:rps401
Synonyms:rps4, rps4a
ORF Names:SPBC19F8.08, SPBC25H2.17c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.08
PomBaseiSPBC19F8.08 rps401

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308391 – 26240S ribosomal protein S4-AAdd BLAST262

Proteomic databases

PaxDbiP87158
PRIDEiP87158

PTM databases

iPTMnetiP87158

Interactioni

Protein-protein interaction databases

BioGridi277174, 58 interactors
STRINGi4896.SPBC19F8.08.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 105S4 RNA-bindingAdd BLAST64

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000231325
InParanoidiP87158
KOiK02987
OMAiRKDYKFP
OrthoDBiEOG092C443N
PhylomeDBiP87158

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
IPR002942 S4_RNA-bd
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PF01479 S4, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

P87158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRGPKKHLK RVAAPHHWLL DKLSGTYAPK PSPGPHKARE CLPLIVFLRN
60 70 80 90 100
RLKYALNGRE VKAILMQRLI KVDGKVRTDS TFPTGFMDVI SVEKTGEHFR
110 120 130 140 150
LVYDIKGRFT VHRITAEEAK YKLCKVKRVQ LGAKGVPFLV THDGRTIRYP
160 170 180 190 200
DPLIKVNDTI KLNLETNKIE SFIKFDTSAQ VMVTGGRNMG RVGTIVHREH
210 220 230 240 250
HLGSFEIIHV KDALDREFAT RLSNVFVIGE TGKSWISLPK GKGVKLSITE
260
ERDRRRALKG LA
Length:262
Mass (Da):29,689
Last modified:November 1, 1998 - v2
Checksum:iFBDCB5D1EB0537C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti9L → F in AAB63866 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA19128.1
U97374 mRNA Translation: AAB63866.1
PIRiT39831
T40012
RefSeqiNP_596350.1, NM_001022270.2

Genome annotation databases

EnsemblFungiiSPBC19F8.08.1; SPBC19F8.08.1:pep; SPBC19F8.08
GeneIDi2540649
KEGGispo:SPBC19F8.08

Similar proteinsi

Entry informationi

Entry nameiRS4A_SCHPO
AccessioniPrimary (citable) accession number: P87158
Secondary accession number(s): O14378
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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