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Protein

Heat shock protein 70 homolog C57A7.12

Gene

SPAC57A7.12

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi39 – 46ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein 70 homolog C57A7.12
Gene namesi
ORF Names:SPAC57A7.12
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC57A7.12
PomBaseiSPAC57A7.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000783991 – 566Heat shock protein 70 homolog C57A7.12Add BLAST566

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei86Phosphoserine1 Publication1
Modified residuei500Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP87142
PaxDbiP87142
PRIDEiP87142

PTM databases

iPTMnetiP87142

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi278607, 3 interactors
IntActiP87142, 1 interactor
STRINGi4896.SPAC57A7.12.1

Structurei

3D structure databases

ProteinModelPortaliP87142
SMRiP87142
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

HOGENOMiHOG000184645
InParanoidiP87142
OMAiNTIVNFR
OrthoDBiEOG092C2CLJ
PhylomeDBiP87142

Family and domain databases

InterProiView protein in InterPro
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 2 hits

Sequencei

Sequence statusi: Complete.

P87142-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLKLTKTLP FSENFIMADS EEYKTVIGIS FGNQNSSIAF NRDGKTDVLA
60 70 80 90 100
NEEGNRQIPS ILSYHGDQEY HGVQARGQLV RNADNSVTNF RDLLGKSHDE
110 120 130 140 150
LTLHHCHYSA NPVNVEGQIG FKITVQEDEE SDPKEKILTA HEASVRHLRR
160 170 180 190 200
LTESAEDFLG TKVNGCVMSV PVYFTDAQRK ALESAANEAG LPVLQLIHDP
210 220 230 240 250
AAVILALMYS EEVLIDKTVV VANFGATRSE VSVVSVKGGL MTILASVHDE
260 270 280 290 300
NLGGEQLTDV LVNFFAKEFE KKNGIDPRKN ARSLAKLRAQ CEITKRVLSN
310 320 330 340 350
GTTASAAVDS LADGIDFHSS INRLRYDLAA SATLNRMADL VTEAVEKANM
360 370 380 390 400
EPFDISEVIL AGGASNTPKL TSLMESIFPE QTIIRSSSSV TPLQLDPSEL
410 420 430 440 450
TAIGSGVQAS LIGHFDAADI AASTDAQVVD VPHLTAPIGI NEGENFVTIF
460 470 480 490 500
DIETALPARK TVEVIAPKEG AAFIPIYEAE RSVKVTKVEP EPIDEEEAFS
510 520 530 540 550
DDEEEEPEEI KERIAIPKTL IATITLPDVS PNAKIELVLQ IDAEGKLTAS
560
ARPKDGKGTN VRGSTA
Length:566
Mass (Da):61,286
Last modified:February 1, 2005 - v3
Checksum:i9381A1793027D93B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti63S → P in BAA13923 (PubMed:9501991).Curated1
Sequence conflicti103L → H in BAA13923 (PubMed:9501991).Curated1
Sequence conflicti110A → S in BAA13923 (PubMed:9501991).Curated1
Sequence conflicti128D → G in BAA13923 (PubMed:9501991).Curated1
Sequence conflicti285A → V in BAA13923 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB08770.1
D89262 mRNA Translation: BAA13923.1
PIRiT38942
T43188
RefSeqiNP_593369.1, NM_001018801.2

Genome annotation databases

EnsemblFungiiSPAC57A7.12.1; SPAC57A7.12.1:pep; SPAC57A7.12
GeneIDi2542131
KEGGispo:SPAC57A7.12

Similar proteinsi

Entry informationi

Entry nameiYDMC_SCHPO
AccessioniPrimary (citable) accession number: P87142
Secondary accession number(s): P78911
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: March 28, 2018
This is version 122 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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