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Protein

Mitochondrial import inner membrane translocase subunit tim17

Gene

tim17

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit tim17
Alternative name(s):
Mitochondrial protein import protein 2
Gene namesi
Name:tim17
ORF Names:SPAC3A12.16c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3A12.16c
PomBaseiSPAC3A12.16c tim17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Transmembranei60 – 77HelicalSequence analysisAdd BLAST18
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei114 – 134HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102951 – 164Mitochondrial import inner membrane translocase subunit tim17Add BLAST164

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi11 ↔ 78By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP87130
PaxDbiP87130
PRIDEiP87130

Interactioni

Subunit structurei

Component of the TIM23 complex, at least composed of tim23, tim17, tim50 and tim50. The complex interacts with the tim44 component of the PAM complex (By similarity).By similarity

Protein-protein interaction databases

STRINGi4896.SPAC3A12.16c.1

Family & Domainsi

Sequence similaritiesi

Belongs to the Tim17/Tim22/Tim23 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000183190
InParanoidiP87130
KOiK17795
OMAiPIIAGNF
OrthoDBiEOG092C5C6F
PhylomeDBiP87130

Family and domain databases

InterProiView protein in InterPro
IPR005678 Tim17
TIGRFAMsiTIGR00980 3a0801so1tim17, 1 hit

Sequencei

Sequence statusi: Complete.

P87130-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASADHTRDP CPYVILNDFG AAFSMGTIGG AIWHSIKGWR NSPPGEKRIS
60 70 80 90 100
AIAAAKTRAP VLGGNFGVWG GLFSTFDCAV KGVRRKEDPW NAIIAGFFTG
110 120 130 140 150
GALAVRGGWR ATRNGAIGCA CILAVFEGLG IALGRMNAEY NRPVAPVIPD
160
APASGSTSAA PAAV
Length:164
Mass (Da):16,901
Last modified:July 1, 1997 - v1
Checksum:i4826B4895F115BCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB08744.1
PIRiT38684
RefSeqiNP_593342.1, NM_001018774.2

Genome annotation databases

EnsemblFungiiSPAC3A12.16c.1; SPAC3A12.16c.1:pep; SPAC3A12.16c
GeneIDi2543163
KEGGispo:SPAC3A12.16c

Similar proteinsi

Entry informationi

Entry nameiTIM17_SCHPO
AccessioniPrimary (citable) accession number: P87130
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: May 23, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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