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Protein

Probable ribonuclease P protein subunit 3

Gene

SPAC3A12.04c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. RNA binding Source: GO_Central

GO - Biological processi

  1. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GO_Central
  2. rRNA processing Source: PomBase
  3. tRNA processing Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribonuclease P protein subunit 3 (EC:3.1.26.5)
Gene namesi
ORF Names:SPAC3A12.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3A12.04c.
PomBaseiSPAC3A12.04c.

Subcellular locationi

  1. Nucleus Curated

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: PomBase
  2. ribonuclease MRP complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Probable ribonuclease P protein subunit 3PRO_0000140033Add
BLAST

Proteomic databases

MaxQBiP87120.

Interactioni

Protein-protein interaction databases

STRINGi4896.SPAC3A12.04c-1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1603.
HOGENOMiHOG000157793.
InParanoidiP87120.
KOiK03539.
OMAiRLYDIIA.
OrthoDBiEOG7X3R34.
PhylomeDBiP87120.

Family and domain databases

InterProiIPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.

Sequencei

Sequence statusi: Complete.

P87120-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFIDLNVVWP TLGVKDLNLV KTVKTLERLG YTAIALNYQY DGKLQNVIKN
60 70 80 90 100
PIVKELYPEQ KIKIYSRITL TIESMPQNKV LSNVTKEFDI LAIRPIGDRL
110 120 130 140 150
LQQTCSDLEF DILSIDFTQR LPFYLKHTFM GLAVSRDIGI EISYSSGLRD
160 170 180 190 200
VSNRRNLITN ATSLVRATRG RGIIVTSETR TPLECRAGFD VINLATFWDL
210 220 230
KQDQARKSVG ESCRSVLLHA ETRRDTYRSI LNGCH
Length:235
Mass (Da):26,799
Last modified:January 31, 2002 - v2
Checksum:i7A1BD68D1306F99D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB08749.2.
PIRiT38672.
RefSeqiNP_593330.1. NM_001018761.1.

Genome annotation databases

EnsemblFungiiSPAC3A12.04c.1; SPAC3A12.04c.1:pep; SPAC3A12.04c.
GeneIDi2543062.
KEGGispo:SPAC3A12.04c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB08749.2.
PIRiT38672.
RefSeqiNP_593330.1. NM_001018761.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4896.SPAC3A12.04c-1.

Proteomic databases

MaxQBiP87120.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3A12.04c.1; SPAC3A12.04c.1:pep; SPAC3A12.04c.
GeneIDi2543062.
KEGGispo:SPAC3A12.04c.

Organism-specific databases

EuPathDBiFungiDB:SPAC3A12.04c.
PomBaseiSPAC3A12.04c.

Phylogenomic databases

eggNOGiCOG1603.
HOGENOMiHOG000157793.
InParanoidiP87120.
KOiK03539.
OMAiRLYDIIA.
OrthoDBiEOG7X3R34.
PhylomeDBiP87120.

Miscellaneous databases

NextBioi20804091.
PROiP87120.

Family and domain databases

InterProiIPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiRNP3_SCHPO
AccessioniPrimary (citable) accession number: P87120
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 31, 2002
Last modified: April 29, 2015
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.