Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptidyl-prolyl cis-trans isomerase ppi1

Gene

ppi1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  • peptidyl-prolyl cis-trans isomerase activity Source: PomBase

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomerase ppi1 (EC:5.2.1.8)
Short name:
PPIase ppi1
Alternative name(s):
Cyclophilin ppi1
Rotamase ppi1
Gene namesi
Name:ppi1
Synonyms:cyp2
ORF Names:SPAC57A10.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC57A10.03.
PomBaseiSPAC57A10.03.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000641761 – 155Peptidyl-prolyl cis-trans isomerase ppi1Add BLAST155

Proteomic databases

MaxQBiP87051.
PRIDEiP87051.

Interactioni

Subunit structurei

Interacts with cwf13/snw1.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
prp45Q098824EBI-1810686,EBI-457758

Protein-protein interaction databases

BioGridi279455. 11 interactors.
IntActiP87051. 1 interactor.
MINTiMINT-4692173.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JB9electron microscopy3.60d1-155[»]
ProteinModelPortaliP87051.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 154PPIase cyclophilin-typePROSITE-ProRule annotationAdd BLAST154

Sequence similaritiesi

Contains 1 PPIase cyclophilin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000065981.
KOiK12733.
OMAiIELYWKH.
OrthoDBiEOG092C5NHS.
PhylomeDBiP87051.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P87051-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANVELQTSL GKILIELYTE HAPKTCQNFY TLAKEGYYDG VIFHRVIPDF
60 70 80 90 100
VIQGGDPTGT GRGGTSIYGD KFDDEIHSDL HHTGAGILSM ANAGPNTNSS
110 120 130 140 150
QFFITLAPTP WLDGKHTIFG RVVSGLSVCK RMGLIRTDSS DRPIEPLKII

KAVAL
Length:155
Mass (Da):16,864
Last modified:July 1, 1997 - v1
Checksum:iE3D1640E30486D21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF337536 mRNA. Translation: AAK14383.1.
CU329670 Genomic DNA. Translation: CAB08166.1.
PIRiT38930.
RefSeqiNP_593308.1. NM_001018738.2.

Genome annotation databases

EnsemblFungiiSPAC57A10.03.1; SPAC57A10.03.1:pep; SPAC57A10.03.
GeneIDi2543019.
KEGGispo:SPAC57A10.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF337536 mRNA. Translation: AAK14383.1.
CU329670 Genomic DNA. Translation: CAB08166.1.
PIRiT38930.
RefSeqiNP_593308.1. NM_001018738.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JB9electron microscopy3.60d1-155[»]
ProteinModelPortaliP87051.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279455. 11 interactors.
IntActiP87051. 1 interactor.
MINTiMINT-4692173.

Proteomic databases

MaxQBiP87051.
PRIDEiP87051.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC57A10.03.1; SPAC57A10.03.1:pep; SPAC57A10.03.
GeneIDi2543019.
KEGGispo:SPAC57A10.03.

Organism-specific databases

EuPathDBiFungiDB:SPAC57A10.03.
PomBaseiSPAC57A10.03.

Phylogenomic databases

HOGENOMiHOG000065981.
KOiK12733.
OMAiIELYWKH.
OrthoDBiEOG092C5NHS.
PhylomeDBiP87051.

Miscellaneous databases

PROiP87051.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPPIL1_SCHPO
AccessioniPrimary (citable) accession number: P87051
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: October 5, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.