Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

G1/S-specific cyclin pas1

Gene

pas1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the pef1 protein kinase. The pef1/pas1 complex activates the res2/cdc10 complex.

GO - Molecular functioni

GO - Biological processi

  • cell division Source: UniProtKB-KW
  • negative regulation of G1/S transition of mitotic cell cycle Source: PomBase
  • negative regulation of sequence-specific DNA binding transcription factor activity Source: PomBase
  • positive regulation of transcription involved in G1/S transition of mitotic cell cycle Source: PomBase
  • regulation of amino acid transmembrane transport Source: PomBase
  • regulation of cyclin-dependent protein serine/threonine kinase activity Source: InterPro
  • regulation of G1/S transition of mitotic cell cycle Source: PomBase
  • regulation of protein stability Source: PomBase
  • signal transduction Source: PomBase
  • traversing start control point of mitotic cell cycle Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Cyclin

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
G1/S-specific cyclin pas1
Gene namesi
Name:pas1
ORF Names:SPAC19E9.03, SPAC57A10.01
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC19E9.03.
PomBaseiSPAC19E9.03. pas1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411G1/S-specific cyclin pas1PRO_0000080506Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi280482. 9 interactions.

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family.Curated

Phylogenomic databases

InParanoidiP87049.
OrthoDBiEOG7BCNR1.

Family and domain databases

InterProiIPR013763. Cyclin-like.
IPR013922. Cyclin_PHO80-like.
[Graphical view]
PfamiPF08613. Cyclin. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

P87049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKVNMRALL ESFSTVILSI YPLAKSTNQQ SHSHSLSLTQ FLYETIRRSR
60 70 80 90 100
VDYTTLLLAL YYFIRFRDAA SSKPTNYIPL LCGRRLFLVC LMAATKFLQD
110 120 130 140 150
RSFSNRAWSR LSGLPVDKLL VLEYMFYQCI DYRLVVPKHI FARWSLLVGE
160 170 180 190 200
CCAHATARYD STDPNVASFG SVAQYWVSLF SNVQSSLDDL FSIACLTKIA
210 220 230 240 250
HRRMNANAAL KNQATRKPSS SPQTTQDSSP ILTMAPSTPV SVGSTPPSTP
260 270 280 290 300
SVLPIAKQLA PMNVCKAHIQ ASNQSRTLTT ASPPEQIPLM EPQVYVNPQV
310 320 330 340 350
LPGRLSSLSK PVSLPPTPSS PKVGVYRPMT SKSNGGVAYC YNAQKLNNAT
360 370 380 390 400
GPVTFNMPFA SVLPLAVSVS CDLGTASAYV ASLPQPCSQK RHLEEDYSCL
410
TEHSAKRRSY F
Length:411
Mass (Da):45,344
Last modified:October 18, 2001 - v3
Checksum:iE9A5B3C7F9227D62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB045126 mRNA. Translation: BAB16401.1.
CU329670 Genomic DNA. Translation: CAC35180.1.
PIRiT38928.
RefSeqiXP_001713050.1. XM_001712998.2.

Genome annotation databases

EnsemblFungiiSPAC19E9.03.1; SPAC19E9.03.1:pep; SPAC19E9.03.
GeneIDi3361406.
KEGGispo:SPAC19E9.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB045126 mRNA. Translation: BAB16401.1.
CU329670 Genomic DNA. Translation: CAC35180.1.
PIRiT38928.
RefSeqiXP_001713050.1. XM_001712998.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi280482. 9 interactions.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC19E9.03.1; SPAC19E9.03.1:pep; SPAC19E9.03.
GeneIDi3361406.
KEGGispo:SPAC19E9.03.

Organism-specific databases

EuPathDBiFungiDB:SPAC19E9.03.
PomBaseiSPAC19E9.03. pas1.

Phylogenomic databases

InParanoidiP87049.
OrthoDBiEOG7BCNR1.

Miscellaneous databases

PROiP87049.

Family and domain databases

InterProiIPR013763. Cyclin-like.
IPR013922. Cyclin_PHO80-like.
[Graphical view]
PfamiPF08613. Cyclin. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A pcl-like cyclin activates the Res2p-Cdc10p cell cycle 'start' transcriptional factor complex in fission yeast."
    Tanaka K., Okayama H.
    Mol. Biol. Cell 11:2845-2862(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: 972 / ATCC 24843.
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiCGP1_SCHPO
AccessioniPrimary (citable) accession number: P87049
Secondary accession number(s): O13840, Q9HGI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: October 18, 2001
Last modified: June 8, 2016
This is version 102 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.