Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.


Streptomyces violaceusniger
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli


Has antifungal activity. Inhibits mycelial growth of wood rotting fungi P.chrysosporium MTCC 787, S.commune ITCC 3751, G.trabeum MTCC 355, P.agaricans ITCC 761, C.versicolor MTCC 138, P.versicolor ITCC 13, P.placenta MTCC 144 and P.friabilis ITCC 335.1 Publication

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.1 Publication

Enzyme regulationi

Inhibited by Hg2+ and, to a lesser extent, by Ag+. Hardly or not at all affected by Fe3+, Mg2+, Co2+, Zn2+, Ca2+, K+, EDTA, beta-mercaptoethanol and N-acetylglucosamine.1 Publication


  1. KM=0.143 mM for p-nitrophenyl-N-acetyl-beta-D-N,N'-diacetylchitobiose1 Publication
  1. Vmax=6.6 µmol/h/mg enzyme with p-nitrophenyl-N-acetyl-beta-D-N,N'-diacetylchitobiose as substrate1 Publication

pH dependencei

Optimum pH is 5 at 37 degrees Celsius. Retains >80% activity after incubation at pH 3-10 for 1 hour.1 Publication

Temperature dependencei

Optimum temperature is 50 degrees Celsius. Retains only 60% and 25% activity after incubation at 30 degrees Celsius and 60 degrees Celsius for 1 hour, respectively.1 Publication

GO - Molecular functioni

GO - Biological processi


Molecular functionAntimicrobial, Fungicide, Glycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Chitinase1 Publication (EC: Publication)
OrganismiStreptomyces violaceusniger
Taxonomic identifieri68280 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

  • Secretedextracellular space 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti


PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004304981 – ›10Chitinase›10


Sequence statusi: Fragment.

Mass (Da):811
Last modified:October 1, 2014 - v1

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei101 Publication1

Entry informationi

Entry nameiCHIT_STRVO
AccessioniPrimary (citable) accession number: P86977
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 2014
Last sequence update: October 1, 2014
Last modified: May 10, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program


Keywords - Technical termi

Direct protein sequencing


  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries