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Protein

Putative chitinase

Gene
N/A
Organism
Pinctada maxima (Silver-lipped pearl oyster) (White-lipped pearl oyster)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.Sequence analysis

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative chitinase (EC:3.2.1.14)
Alternative name(s):
Chitinase-like protein 3
Short name:
Clp3
OrganismiPinctada maxima (Silver-lipped pearl oyster) (White-lipped pearl oyster)
Taxonomic identifieri104660 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPterioidaPterioideaPteriidaePinctada

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000041306918 – 466Putative chitinaseSequence analysisAdd BLAST449

Expressioni

Tissue specificityi

Prismatic layer of shell (at protein level). Expressed primarily in the mantle with highest level in the mantle edge and lower level in the mantle pallium.1 Publication

Structurei

3D structure databases

SMRiP86955.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili408 – 442Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the glycosyl hydrolase 18 family.Curated

Keywords - Domaini

Coiled coil, Signal

Family and domain databases

Gene3Di3.10.50.10. 1 hit.
InterProiView protein in InterPro
IPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SMARTiView protein in SMART
SM00636. Glyco_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P86955-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLTIWLVSI LALGTWGQKF NRFCHYNSWA LSRNPQHGLV PEDIDPFLCT
60 70 80 90 100
HLILGFAEID ESGLRLKDPN HYQQEYLYQR IVRLRRINPR LNMILSVGGW
110 120 130 140 150
DKSQEGYSKL VSSRENILFF TKWIITYLRR HDFDGLDLDW EYPTFKGSPM
160 170 180 190 200
GDKKKFVDLV ENLAYEFDIE EIPDIKWKLT LTWTADPLES VRTSAYDIKG
210 220 230 240 250
IASKVHNVNL KMYDFHGHWD DPLQVNHHSP LTSPNSPRNV NELAKSWVKA
260 270 280 290 300
GVRIEKLILG IPFFGRSFTL KTANMSVPGS PAVGPGSDFG DGIPIHNLCH
310 320 330 340 350
IIRGGTKELY LPEKKVPYIV SGSEWIGYDN PRSVMEKAQL VFNNALAGVM
360 370 380 390 400
IYSLDMDDHH GTCGRKWPMM MAVIHGLNAY MEYIDSKHKS LELTFNKKIL
410 420 430 440 450
RARVSLRNYR RRNQQEKVAE MEQRIRHLEQ ELQQSMGNMA YERQQAQAML
460
NRGVSLPPIE QQSWSW
Length:466
Mass (Da):53,984
Last modified:October 19, 2011 - v1
Checksum:iC1563E0E9C18068B
GO

Sequence cautioni

The sequence GT281452 differs from that shown. Reason: Frameshift at positions 459 and 462.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti135G → C in GT282837 (PubMed:19915030).Curated1
Sequence conflicti148S → N in GT278709 (PubMed:19915030).Curated1
Sequence conflicti263 – 264FF → LL in GT282837 (PubMed:19915030).Curated2
Sequence conflicti279 – 281GSP → RIA in GT282837 (PubMed:19915030).Curated3
Sequence conflicti402A → S in GT281452 (PubMed:19915030).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GT278709 mRNA. No translation available.
GT280136 mRNA. No translation available.
GT281452 mRNA. No translation available.
GT281952 mRNA. No translation available.
GT282837 mRNA. No translation available.
EZ420284 mRNA. No translation available.

Similar proteinsi

Entry informationi

Entry nameiCHI_PINMA
AccessioniPrimary (citable) accession number: P86955
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 10, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families